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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

Cas:277299-70-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one supplier in China

Cas:277299-70-4

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Sinoway Industrial Co., Ltd.

Purity: 98% up Storage:room temprature Package:25kg/drum Application:Eltraombopag intermediate Port:Beijing/Shanghai/Shenzhen/Hangzhou

2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one, Eltraombopag intermediate

Cas:277299-70-4

Min.Order:1 Kilogram

FOB Price: $320.0 / 400.0

Type:Trading Company

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Oxo-2,4,5,6,7,7a-hexahydrothieno[3,2-c]pyridine hydrochloride

Cas:277299-70-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

2- (3, 4-Dimethylphenyl) -1, 2-Dihydro-5-Methyl-3h-Pyrazol-3-One CAS 277299-70-4

Cas:277299-70-4

Min.Order:1 Gram

FOB Price: $6.0 / 9.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate. In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so o

TIANFU CHEM 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

Cas:277299-70-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 277299-70-4 with competitive price

Cas:277299-70-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is

2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one CAS NO 277299-70-4

Cas:277299-70-4

Min.Order:1 Kilogram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

3H-Pyrazol-3-one,2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl- 277299-70-4

Cas:277299-70-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one CAS:277299-70-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates,

2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one CAS:277299-70-4

Cas:277299-70-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

3H-Pyrazol-3-one,2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-

Cas:277299-70-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Guangdong Juda Chemical Industrial Co.,Limited

1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. 3) OEM/ODM Available; 4) Reasonable & Compet

High Quality 2-(3.4-Dimethylphenyl)-1.2-dihydro-5-methyl-3H-pyrazol-3-one CAS 277299-70-4

Cas:277299-70-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

3H-Pyrazol-3-one,2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-

Cas:277299-70-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Wuhan Zenuo Biological Medicine Technology Co Ltd

Product Name: 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one Synonyms: 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one;2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one;2-(3,4-dimethylphenyl)-5-methyl-1,2-dihydro-3H

2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one Manufactory best quality

Cas:277299-70-4

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

high purity 2-(3,4-Dimethyl-phenyl)-5-methyl-1,2-dihydro-pyrazol-3-one

Cas:277299-70-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

1-(3,4-dimethylphenyl)-3-methyl-1H-pyrazol-5-ol

Cas:277299-70-4

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3H-Pyrazol-3-one,2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-

Cas:277299-70-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

Cas:277299-70-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd. established since 2009 , has been always focusing on supplying products and services to our clients in the field of small molecule drug. Huarong Pharm has built platforms for the research, development and manufac

2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

Cas:277299-70-4

Min.Order:1 Gram

FOB Price: $1.0 / 2.0

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

2-(3,4-Dimethyl-phenyl)-5-methyl-1,2-dihydro-pyrazol-3-one

Cas:277299-70-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

2-(3,4-dimethylphenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one

Cas:277299-70-4

Min.Order:1 Milligram

Negotiable

Type:Trading Company

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

Cas:277299-70-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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NANJING SUNNY PHARMATECH CO., LTD

Our product has a very high quality and now we are exporting to customers overseas with very positive feedback. With best price, quality and service from Nanjing Sunny, we are confident to set up a very nice cooperation with customers all over the w

2-(3,4-Dimethylphenyl) -1,2-dihydro-5-methyl- 3H-pyrazol-3-one

Cas:277299-70-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Wuhu Nuowei Chemistry Technologies Co., Ltd.

Wuhu Nuovo Chemical Technology Co., Ltd. was established in August 2014, mainly engaged in the development, production and sales of ionic liquids, ribose, nucleosides, nucleotides and related chemicals; Products are mainly used in new energy, new ma

2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

Cas:277299-70-4

Min.Order:100 Gram

Negotiable

Type:Manufacturers

inquiry

Senova Technology Company Limited

1.High quality 2.High purity 3.Best price 4.Best service 5.Professional manufacturer 6.Loyal and honest supplier 7.Fast response to customer within 6 hours Application:Pharmaceutical Intermediate

2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

Cas:277299-70-4

Min.Order:200 Gram

Negotiable

Type:Trading Company

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SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

SAGECHEM/2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

Cas:277299-70-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

Cas:277299-70-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

Eltrombopag intermediate 1

Cas:277299-70-4

Min.Order:1 Kilogram

Negotiable

Type:Other

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Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Cas no.277299-70-4 98% 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

Cas:277299-70-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Luyunjia Chemistry Xiamen Limited

Luyunjia Chemistry Xiamen Limited is a high-tech company specializing in R&D and manufacturing of photoinitiators monomers and oligomers, UV absorbers and pharmaceutical intermediates, and pharmaceutical intermediates of generic drug. and has a h

hight quality 2-(3,4-dimethylphenyl)-5-methyl-1,2-dihydro-3Hpyrazol-3-one 277299-70-4/18048-64-1/925633-57-4

Cas:277299-70-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Synthetic route

ethyl acetoacetate
141-97-9

ethyl acetoacetate

3,4-dimethylphenylhydrazine hydrochloride
60481-51-8, 86746-50-1

3,4-dimethylphenylhydrazine hydrochloride

2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
277299-70-4

2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

Conditions
ConditionsYield
With sodium bicarbonate; sodium acetate In diethyl ether; acetic acid76%
With sodium acetate In acetic acid for 24h; Heating / reflux;76%
With sodium acetate; acetic acid for 24h; Reflux;76%
ethyl acetoacetate
141-97-9

ethyl acetoacetate

3,4-dimethylphenylhydrazine
13636-53-8

3,4-dimethylphenylhydrazine

2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
277299-70-4

2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

Conditions
ConditionsYield
In acetic acid64%
2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
277299-70-4

2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

2-amino-6-bromophenol
28165-50-6

2-amino-6-bromophenol

1-(3,4-dimethylphenyl)-3-methyl-4-(3-bromo-2-hydroxyphenyl)hydrazono-5-pyrazolone

1-(3,4-dimethylphenyl)-3-methyl-4-(3-bromo-2-hydroxyphenyl)hydrazono-5-pyrazolone

Conditions
ConditionsYield
Stage #1: 2-amino-6-bromophenol With hydrogenchloride; sodium nitrite In ethanol; water at 0 - 10℃;
Stage #2: 2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one With triethylamine In ethanol; water at 20 - 30℃; for 2h; Reagent/catalyst;
98%
2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
277299-70-4

2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

3'-amino-2'-hydroxy-1,1'-biphenyl-3-carboxylic acid hydrochloride
376591-97-8

3'-amino-2'-hydroxy-1,1'-biphenyl-3-carboxylic acid hydrochloride

3’-{N’-[1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-di-hydropyrazol-4-ylidene]hydrazino}-2’-hydroxybiphenyl-3-carboxylic acid
376591-99-0

3’-{N’-[1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-di-hydropyrazol-4-ylidene]hydrazino}-2’-hydroxybiphenyl-3-carboxylic acid

Conditions
ConditionsYield
Stage #1: 3'-amino-2'-hydroxy-1,1'-biphenyl-3-carboxylic acid hydrochloride With hydrogenchloride; sodium nitrite In methanol; water for 2.5h; pH=1-2;
Stage #2: 2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one With sodium hydrogencarbonate In methanol; water at 20℃; for 12h; pH=8;
Stage #3: With hydrogenchloride In methanol; water at 0 - 20℃; for 3h; pH=1-2;
90%
2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
277299-70-4

2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

3-amino-4-hydroxybenzoic acid
1571-72-8

3-amino-4-hydroxybenzoic acid

3-{[1-(3,4-dimethylphenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]azo}-4-hydroxybenzoic acid

3-{[1-(3,4-dimethylphenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]azo}-4-hydroxybenzoic acid

Conditions
ConditionsYield
82%
2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
277299-70-4

2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

4-{[1-(3,4-dimethylphenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]azo}-3-hydroxybenzoic acid

4-{[1-(3,4-dimethylphenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]azo}-3-hydroxybenzoic acid

Conditions
ConditionsYield
82%
2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
277299-70-4

2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

3′-amino-2′-hydroxy biphenyl-3-carboxylic acid
376592-93-7

3′-amino-2′-hydroxy biphenyl-3-carboxylic acid

triethylamine
121-44-8

triethylamine

eltrombopag triethylamine salt

eltrombopag triethylamine salt

Conditions
ConditionsYield
Stage #1: 3'-amino-2'-hydroxy-1,1'-biphenyl-3-carboxylic acid With hydrogenchloride; sodium nitrite In methanol; water at 0 - 10℃; for 1.25h;
Stage #2: 2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one; triethylamine at 0 - 60℃; for 4h; pH=6 - 8; pH-value;
76%
2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
277299-70-4

2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

2-amino-phenol
95-55-6

2-amino-phenol

eltrombopag olamine

eltrombopag olamine

Conditions
ConditionsYield
Stage #1: 2-amino-phenol With hydrogenchloride; sodium nitrite In methanol; water at 75 - 80℃; for 24h;
Stage #2: 2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one With triethylamine In methanol; water at 0 - 25℃; for 2.5h;
68%
2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
277299-70-4

2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

C13H11NO3*ClH
376591-78-5

C13H11NO3*ClH

4'-{N'-[1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydropyrazol-4-ylidene]hydrazino}-3'-hydroxybiphenyl-4-carboxylic acid
376591-84-3

4'-{N'-[1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydropyrazol-4-ylidene]hydrazino}-3'-hydroxybiphenyl-4-carboxylic acid

Conditions
ConditionsYield
Stage #1: C13H11NO3*ClH With hydrogenchloride; sodium nitrite In water at 5℃; for 0.166667h;
Stage #2: 2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one With sodium hydrogencarbonate In ethanol; water at 20℃; for 24h; pH=7 - 8;
35%
2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
277299-70-4

2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

5-chloro-3-{[1-(3,4-dimethylphenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]azo}-2-hydroxybenzenesulfonic acid

5-chloro-3-{[1-(3,4-dimethylphenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]azo}-2-hydroxybenzenesulfonic acid

Conditions
ConditionsYield
34%
2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
277299-70-4

2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

3-aminosalicylic acid
570-23-0

3-aminosalicylic acid

3-{[1-(3,4-dimethylphenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]azo}-2-hydroxybenzoic acid

3-{[1-(3,4-dimethylphenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]azo}-2-hydroxybenzoic acid

Conditions
ConditionsYield
32%
2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
277299-70-4

2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

3′-amino-2′-hydroxy biphenyl-3-carboxylic acid
376592-93-7

3′-amino-2′-hydroxy biphenyl-3-carboxylic acid

eltrombopag olamine

eltrombopag olamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: hydrogenchloride; sodium nitrite / methanol; water / 1.25 h / 0 - 10 °C
1.2: 4 h / 0 - 60 °C / pH 6 - 8
2.1: methanol / 7.5 h / 25 - 60 °C
View Scheme
2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
277299-70-4

2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

2-bromo-6-nitro-phenol
13073-25-1

2-bromo-6-nitro-phenol

3-Carboxyphenylboronic acid
25487-66-5

3-Carboxyphenylboronic acid

Eltrombopag

Eltrombopag

Conditions
ConditionsYield
Stage #1: 2-bromo-6-nitro-phenol With benzyl bromide; potassium carbonate In acetonitrile at 90℃; for 3h;
Stage #2: 3-Carboxyphenylboronic acid With potassium carbonate; palladium dichloride In 1,4-dioxane; water at 50℃; under 7500.75 Torr; for 4h; Inert atmosphere;
Stage #3: 2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one Further stages;

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