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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 5-Fluoro-2-Methylbenzoic Acid supplier in China

Cas:33184-16-6

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

Our Services 1. Certificate Of Analysis (COA) 2. Material Safety Data Sheet (MSDS) 3. Route of synthesis (ROS) 4. Method of Aanlysis (MOA)

5-Fluoro-2-methylbenzoic acid

Cas:33184-16-6

Min.Order:1 Gram

FOB Price: $8.0

Type:Lab/Research institutions

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Hangzhou Think Chemical Co. Ltd

5-Fluoro-2-methylbenzoic acid CAS No.:33184-16-6 Name: 5-Fluoro-2-methylbenzoic acid Synonyms: 5-Fluoro-o-toluic acid Molecular Structure: Molecular Formula: C8H7FO2 Molecular Weight:

High purity 5-Fluoro-2-methylbenzoic acid CAS No.:33184-16-6

Cas:33184-16-6

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Other

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Name 5-Fluoro-2-methylbenzoic acid Synonyms 5-Fluoro-o-toluic acid Molecular Structure Molecular Formula

5-Fluoro-2-methylbenzoic acid

Cas:33184-16-6

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

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ANQING CHICO PHARMACEUTICAL CO.,LTD.

High quality. Factory supply. In stock. Best price.1.Quick response within 24 hours;2.Best quality in your requirement;?3.We pay more attention on delivery time, and usually ship on time;4.Under the premise of safety and effectiveness, we can produce

5-fluoro-2-methylbenzoic acid

Cas:33184-16-6

Min.Order:0

Negotiable

Type:Trading Company

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis

5-Fluoro-2-methylbenzoic acid

Cas:33184-16-6

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

5-Fluoro-o-toluic acid (COOH=1)

Cas:33184-16-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 33184-16-6 with best quality

Cas:33184-16-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

5-Fluoro-2-methylbenzoic acid 33184-16-6

Cas:33184-16-6

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product Name: 5-Fluoro-2-methylbenzoic acid Synonyms: RARECHEM AL BO 0443;2-METHYL-5-FLUOROBENZOIC ACID;5-FLUORO-2-METHYLBENZOIC ACID;5-FLUORO-O-TOLUIC ACID;5-Fluoro-2-Methyl Benzoic Acid 2-Me

5-Fluoro-2-methylbenzoic acid CAS: 33184-16-6

Cas:33184-16-6

Min.Order:5 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzoic acid, 5-fluoro-2-methyl- 33184-16-6

Cas:33184-16-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Pharmaceutical Intermediate, 5-Fluoro-2-methylbenzoic acid CAS:33184-16-6

Cas:33184-16-6

Min.Order:1 Gram

FOB Price: $16.0 / 21.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

5-Fluoro-2-methylbenzoic acid CAS:33184-16-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality org

5-Fluoro-2-methylbenzoic acid CAS:33184-16-6

Cas:33184-16-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Benzoic acid, 5-fluoro-2-methyl-/ LIDE PHARMA- Factory supply / Best price

Cas:33184-16-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:33184-16-6

Cas:33184-16-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

5-Fluoro-2-Methylbenzoic Acid

Cas:33184-16-6

Min.Order:0

Negotiable

Type:Manufacturers

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

5-Fluoro-2-methylbenzoic?acid

Cas:33184-16-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

ACHIEVER SYSTEAM BIOCHEM CO., LTD.

We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to provide excellence in researching, manufacturing and drug discovery process. Our

5-Fluoro-2-methylbenzoic acid

Cas:33184-16-6

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 5-fluoro-2-methylbenzoic acid

Cas:33184-16-6

Min.Order:0 Metric Ton

Negotiable

Type:Other

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Benzoic acid, 5-fluoro-2-methyl-

Cas:33184-16-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

5-Fluoro-2-methylbenzoic acid

Cas:33184-16-6

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

5-Fluoro-2-methylbenzoic acid

Cas:33184-16-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Siwei Development Group Ltd.

Product name: 5-Fluoro-2-Methylbenzoic Acid CAS No.:33184-16-6 Molecule Formula:C8H6FO2 Molecule Weight:153.13 Purity: 98.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard TES

High Quality 5-Fluoro-2-Methylbenzoic Acid on stock

Cas:33184-16-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

33184-16-6 5-Fluoro-2-methylbenzoic acid

Cas:33184-16-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

5-Fluoro-2-methylbenzoic acid

Cas:33184-16-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

5-Fluoro-2-methylbenzoicacid

Cas:33184-16-6

Min.Order:1 Milligram

Negotiable

Type:Trading Company

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

5-Fluoro-2-methylbenzoic acid

Cas:33184-16-6

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

5-Fluoro-2-methylbenzoic acid

Cas:33184-16-6

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 5-Fluoro-2-methylbenzoic acid Synonyms: 2-METHYL-5-FLUOROBENZOIC ACID;RARECHEM AL BO 0443;5-Fluoro-2-Methyl Benzoic Acid 2-Methyl-5-Fluorobenzoic Acid;5-Fluoro-2-methylbenzoic acid 99%;5-Fluoro-2-methylbenzoicacid99%;5-FLUORO-2-ME

5-Fluoro-2-methylbenzoic acid

Cas:33184-16-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

5-Fluoro-2-methylbenzoic acid

Cas:33184-16-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

carbon dioxide
124-38-9

carbon dioxide

5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

Conditions
ConditionsYield
Stage #1: 2-bromo-4-fluorotoluene With magnesium In diethyl ether for 2h; Grignard Reaction; Heating / reflux;
Stage #2: carbon dioxide In diethyl ether Grignard Reaction;
Stage #3: With hydrogenchloride In water; ethyl acetate Grignard Reaction;
59%
carbon dioxide
124-38-9

carbon dioxide

2-chloro-4-fluorotoluene
452-73-3

2-chloro-4-fluorotoluene

5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

Conditions
ConditionsYield
Stage #1: 2-chloro-4-fluorotoluene With magnesium at 55℃; for 11h; Inert atmosphere;
Stage #2: carbon dioxide With hydrogenchloride In water at 0 - 10℃; pH=1 - 2;
2-bromo-4-fluorotoluene
1422-53-3

2-bromo-4-fluorotoluene

carbon dioxide
124-38-9

carbon dioxide

5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

Conditions
ConditionsYield
Stage #1: 2-bromo-4-fluorotoluene With magnesium In tetrahydrofuran at 25℃; for 4h; Inert atmosphere; Reflux;
Stage #2: carbon dioxide With hydrogenchloride In water at 0 - 10℃; pH=1 - 2;
carbon dioxide
124-38-9

carbon dioxide

4-fluoro-2-iodotoluene
13194-67-7

4-fluoro-2-iodotoluene

5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

Conditions
ConditionsYield
Stage #1: 4-fluoro-2-iodotoluene With magnesium In tetrahydrofuran at 25 - 50℃; for 4h; Inert atmosphere; Reflux;
Stage #2: carbon dioxide With hydrogenchloride In water at 0 - 10℃; pH=1 - 2;
5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

methyl iodide
74-88-4

methyl iodide

5-fluoro-2-methylbenzoic acid methyl ester
175278-29-2

5-fluoro-2-methylbenzoic acid methyl ester

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 16h;99%
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃; for 2h;90%
5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

1-bromo-2-(triisopropylsilyl)acetylene
111409-79-1

1-bromo-2-(triisopropylsilyl)acetylene

3-fluoro-6-methyl-2-((triisopropylsilyl)ethynyl)benzoic acid

3-fluoro-6-methyl-2-((triisopropylsilyl)ethynyl)benzoic acid

Conditions
ConditionsYield
With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; potassium hydrogencarbonate In tert-Amyl alcohol at 30℃; for 24h;96%
With [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; potassium carbonate In tert-Amyl alcohol at 80℃; for 24h; Sealed tube; Schlenk technique;86%
5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

3-fluoro-2-iodo-6-methylbenzoic acid
1417190-24-9

3-fluoro-2-iodo-6-methylbenzoic acid

Conditions
ConditionsYield
With N-iodo-succinimide; palladium diacetate In N,N-dimethyl-formamide89.7%
With [bis(acetoxy)iodo]benzene; iodine; palladium diacetate In N,N-dimethyl-formamide at 100℃; for 18h; Inert atmosphere;
With [bis(acetoxy)iodo]benzene; iodine; palladium diacetate In N,N-dimethyl-formamide at 100℃; for 16h;80 g
With N-iodo-succinimide; palladium diacetate In N,N-dimethyl-formamide at 110℃; for 15h;25 g
methanol
67-56-1

methanol

5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

5-fluoro-2-methylbenzoic acid methyl ester
175278-29-2

5-fluoro-2-methylbenzoic acid methyl ester

Conditions
ConditionsYield
With sulfuric acid at 60℃;89%
With sulfuric acid for 24h; Heating;
With thionyl chloride for 4h; Heating;
5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

5-fluoro-2-methylbenzaldehyde
22062-53-9

5-fluoro-2-methylbenzaldehyde

Conditions
ConditionsYield
With dipotassium hydrogenphosphate; fac-tris(2-phenylpyridinato-N,C2')iridium(III); tris-(trimethylsilyl)silane; dimethyl dicarbonate In acetonitrile at 20℃; for 6h; Schlenk technique; Inert atmosphere; Sealed tube; Irradiation;85%
oct-1-en-3-one
4312-99-6

oct-1-en-3-one

5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

4-fluoro-7-methyl-2-(3-oxooctyl)-2,3-dihydro-1H-inden-1-one

4-fluoro-7-methyl-2-(3-oxooctyl)-2,3-dihydro-1H-inden-1-one

Conditions
ConditionsYield
With manganese(II)carbonate; [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2 In water; acetonitrile at 150℃; for 20h; Inert atmosphere;83%
5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

methylamine
74-89-5

methylamine

5-fluoro-N,2-dimethylbenzamide
1332325-17-3

5-fluoro-N,2-dimethylbenzamide

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃; for 6.5h; Inert atmosphere;82%
2-methyl-4-(2-(2R)-methyl-[1,3'(3'S)]bipyrrolidinyl-1'-yl)-phenylamine
1146415-75-9

2-methyl-4-(2-(2R)-methyl-[1,3'(3'S)]bipyrrolidinyl-1'-yl)-phenylamine

5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

(2R,3'S)-5-fluoro-2-methyl-N-[2-methyl-4-(2-methyl[1,3']bipyrrolidinyl-1'-yl) phenyl]benzamide
1146699-80-0

(2R,3'S)-5-fluoro-2-methyl-N-[2-methyl-4-(2-methyl[1,3']bipyrrolidinyl-1'-yl) phenyl]benzamide

Conditions
ConditionsYield
With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane; N,N-dimethyl-formamide at 0 - 20℃;82%
2-methyl-4-(2-(2S)-methyl-[1,3'(3'R)]bipyrrolidinyl-1'-yl)-phenylamine
1146415-72-6

2-methyl-4-(2-(2S)-methyl-[1,3'(3'R)]bipyrrolidinyl-1'-yl)-phenylamine

5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

(2S,3'R)-5-fluoro-2-methyl-N-[2-methyl-4-(2-methyl[1,3']bipyrrolidinyl-1'-yl) phenyl]benzamide

(2S,3'R)-5-fluoro-2-methyl-N-[2-methyl-4-(2-methyl[1,3']bipyrrolidinyl-1'-yl) phenyl]benzamide

Conditions
ConditionsYield
With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane; N,N-dimethyl-formamide at 0 - 20℃;82%
2-methyl-4-(2-(2S)-methyl-[1,3'(3'S)]bipyrrolidinyl-1'-yl)-phenylamine
1056623-62-1

2-methyl-4-(2-(2S)-methyl-[1,3'(3'S)]bipyrrolidinyl-1'-yl)-phenylamine

5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

(2S,3'S)-5-fluoro-2-methyl-N-[2-methyl-4-(2-methyl[1,3']bipyrrolidinyl-1'-yl) phenyl]benzamide
1146699-86-6

(2S,3'S)-5-fluoro-2-methyl-N-[2-methyl-4-(2-methyl[1,3']bipyrrolidinyl-1'-yl) phenyl]benzamide

Conditions
ConditionsYield
With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane; N,N-dimethyl-formamide at 0 - 20℃;82%
2-methyl-4-(2(2R)-methyl-[1,3'(3'R)]bipyrrolidinyl-1'-yl)-phenylamine
1146415-77-1

2-methyl-4-(2(2R)-methyl-[1,3'(3'R)]bipyrrolidinyl-1'-yl)-phenylamine

5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

(2R,3'R)-5-fluoro-2-methyl-N-[2-methyl-4-(2-methyl[1,3']bipyrrolidinyl-1'-yl) phenyl]benzamide
1146852-39-2

(2R,3'R)-5-fluoro-2-methyl-N-[2-methyl-4-(2-methyl[1,3']bipyrrolidinyl-1'-yl) phenyl]benzamide

Conditions
ConditionsYield
With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane; N,N-dimethyl-formamide at 0 - 20℃;82%
5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

5-phenyl-1-penten-3-one
53931-59-2

5-phenyl-1-penten-3-one

4-fluoro-7-methyl-2-(3-oxo-5-phenylpentyl)-2,3-dihydro-1Hinden-1-one

4-fluoro-7-methyl-2-(3-oxo-5-phenylpentyl)-2,3-dihydro-1Hinden-1-one

Conditions
ConditionsYield
With manganese(II)carbonate; [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2 In water; acetonitrile at 150℃; for 20h; Inert atmosphere;82%
5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

triphenylantimony dichloride
594-31-0, 34716-91-1, 20265-29-6

triphenylantimony dichloride

bis(5-fluoro-2-methylbenzoato)triphenylantimony(V)

bis(5-fluoro-2-methylbenzoato)triphenylantimony(V)

Conditions
ConditionsYield
With sodium ethoxide In methanol under N2, Schlenk techniques; soln. of benzoic acid deriv. and EtONa in MeOH stirred for 30 min, Ph3SbCl2 added, mixt. stirred at room temp. for12 h; evapn. under vac., recrystd. from CH2Cl2/ether (1/1); elem. anal.;80%
5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

tetraphenylantimony(V) bromide
16894-69-2

tetraphenylantimony(V) bromide

(5-fluoro-2-methylbenzoato)tetraphenylantimony(V)

(5-fluoro-2-methylbenzoato)tetraphenylantimony(V)

Conditions
ConditionsYield
With sodium ethoxide In methanol under N2, Schlenk techniques; soln. of benzoic acid deriv. and EtONa in MeOH stirred for 30 min, Ph4SbBr added, mixt. stirred at room temp. for 12 h; evapn. under vac., recrystd. from CH2Cl2/petroleum ether (1/1); elem. anal.;80%
ethanol
64-17-5

ethanol

5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

ethyl 2-methyl-5-fluorobenzoate

ethyl 2-methyl-5-fluorobenzoate

Conditions
ConditionsYield
With sulfuric acid at 100℃; for 12h; Sealed tube;80%
5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

5-fluoro-2-methylbenzoic acid methyl ester
175278-29-2

5-fluoro-2-methylbenzoic acid methyl ester

Conditions
ConditionsYield
With sulfuric acid In methanol78%
4-penten-3-one
1629-58-9

4-penten-3-one

5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

3-fluoro-6-methyl-2-(3-oxopentyl)benzoic acid

3-fluoro-6-methyl-2-(3-oxopentyl)benzoic acid

Conditions
ConditionsYield
With [RhCl2(p-cymene)]2 In water at 95℃; for 12h; Sealed tube;78%
dec-1-en-3-one
56606-79-2

dec-1-en-3-one

5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

4-fluoro-7-methyl-2-(3-oxodecyl)-2,3-dihydro-1H-inden-1-one

4-fluoro-7-methyl-2-(3-oxodecyl)-2,3-dihydro-1H-inden-1-one

Conditions
ConditionsYield
With manganese(II)carbonate; [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2 In water; acetonitrile at 150℃; for 20h; Inert atmosphere;78%
5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

1,1'-carbonyldiimidazole
530-62-1

1,1'-carbonyldiimidazole

2-methyl-5-fluorobenzamide

2-methyl-5-fluorobenzamide

Conditions
ConditionsYield
Stage #1: 5-fluoro-2-methylbenzoic acid; 1,1'-carbonyldiimidazole In dichloromethane at 35℃; for 1h;
Stage #2: With ammonia In dichloromethane at 35℃; for 2h;
77.6%
5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

5-fluoro-2-methylbenzoyl chloride
21900-39-0

5-fluoro-2-methylbenzoyl chloride

Conditions
ConditionsYield
With thionyl chloride for 3h; Reflux;77%
With thionyl chloride
With thionyl chloride In toluene
non-1-en-3-one
24415-26-7

non-1-en-3-one

5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

4-fluoro-7-methyl-2-(3-oxononyl)-2,3-dihydro-1H-inden-1-one

4-fluoro-7-methyl-2-(3-oxononyl)-2,3-dihydro-1H-inden-1-one

Conditions
ConditionsYield
With manganese(II)carbonate; [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2 In water; acetonitrile at 150℃; for 20h; Inert atmosphere;77%
dodec-1-en-3-one
58879-39-3

dodec-1-en-3-one

5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

4-fluoro-7-methyl-2-(3-oxododecyl)-2,3-dihydro-1H-inden-1-one

4-fluoro-7-methyl-2-(3-oxododecyl)-2,3-dihydro-1H-inden-1-one

Conditions
ConditionsYield
With manganese(II)carbonate; [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2 In water; acetonitrile at 150℃; for 20h; Inert atmosphere;77%
5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

Phenyl vinyl ketone
768-03-6

Phenyl vinyl ketone

4-fluoro-7-methyl-2-(3-oxo-3-phenylpropyl)-2,3-dihydro-1Hinden-1-one

4-fluoro-7-methyl-2-(3-oxo-3-phenylpropyl)-2,3-dihydro-1Hinden-1-one

Conditions
ConditionsYield
With manganese(II)carbonate; [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2 In water; acetonitrile at 150℃; for 20h; Inert atmosphere;76%
octyl vinyl ketone
42832-47-3

octyl vinyl ketone

5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

4-fluoro-7-methyl-2-(3-oxoundecyl)-2,3-dihydro-1H-inden-1-one

4-fluoro-7-methyl-2-(3-oxoundecyl)-2,3-dihydro-1H-inden-1-one

Conditions
ConditionsYield
With manganese(II)carbonate; [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2 In water; acetonitrile at 150℃; for 20h; Inert atmosphere;74%
tetradec-1-en-3-one
26496-24-2

tetradec-1-en-3-one

5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

4-fluoro-7-methyl-2-(3-oxotetradecyl)-2,3-dihydro-1H-inden-1-one

4-fluoro-7-methyl-2-(3-oxotetradecyl)-2,3-dihydro-1H-inden-1-one

Conditions
ConditionsYield
With manganese(II)carbonate; [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2 In water; acetonitrile at 150℃; for 20h; Inert atmosphere;72%
5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

2-methyl-3-nitro-5-fluorobenzoic acid
850462-64-5

2-methyl-3-nitro-5-fluorobenzoic acid

Conditions
ConditionsYield
With sulfuric acid; nitric acid In dichloromethane at 30 - 40℃; for 3h; Temperature; Reagent/catalyst;70.5%
With sulfuric acid; nitric acid at -110 - -15℃; for 4.5h;45.1%
With sulfuric acid; nitric acid at 0℃; for 0.5h; Nitration;
5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

acetonitrile
75-05-8

acetonitrile

2-acetyl-6-fluoroisoindolin-1-one

2-acetyl-6-fluoroisoindolin-1-one

Conditions
ConditionsYield
With iron(III)-acetylacetonate; copper(II) nitrate; Selectfluor at 80℃; for 8h; Schlenk technique; Inert atmosphere;70%
N-methylmaleimide
930-88-1

N-methylmaleimide

5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

C12H12FNO2

C12H12FNO2

Conditions
ConditionsYield
With sodium dihydrogenphosphate; [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; water at 85℃; for 16h; Green chemistry; chemoselective reaction;70%
5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

2-bromo-5-fluorobenzamide
1006-34-4

2-bromo-5-fluorobenzamide

Conditions
ConditionsYield
Stage #1: 5-fluoro-2-methylbenzoic acid With thionyl chloride at 70℃; for 20h;
Stage #2: With ammonium hydroxide In water at 20℃; for 1h;
69%
2-aminopyridine
504-29-0

2-aminopyridine

5-fluoro-2-methylbenzoic acid
33184-16-6

5-fluoro-2-methylbenzoic acid

C13H11FN2O

C13H11FN2O

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃;68%

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