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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

(S)-ADAMANTYLGLYCINE

Cas:361441-97-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 361441-97-6 with best quality

Cas:361441-97-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

(S) - N- Boc- adamantylglycine

Cas:361441-97-6

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

(S)-Adamantylglycine

Cas:361441-97-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

(S) - N- Boc- adamantylglycine CAS:361441-97-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality o

(S) - N- Boc- adamantylglycine CAS:361441-97-6

Cas:361441-97-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

(S)-Adamantylglycine

Cas:361441-97-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

(S) - N- Boc- adamantylglycine

Cas:361441-97-6

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

(S)-Adamantylglycine

Cas:361441-97-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

N-Boc-L-adamantylglycine price Purchase

Cas:361441-97-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

(2S)-2-(Adamantan-1-yl)-2-((tert-butoxycarbonyl)amino)aceticacid

Cas:361441-97-6

Min.Order:1 Milligram

Negotiable

Type:Trading Company

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GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

(S) - N- Boc- adamantylglycine

Cas:361441-97-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

N-Boc-L-adamantylglycine

Cas:361441-97-6

Min.Order:0

Negotiable

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

(S)-Adamantylglycine

Cas:361441-97-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

(S)-Adamantylglycine

Cas:361441-97-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:white powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as primary a

N-BoC-L-Adamantylglycine

Cas:361441-97-6

Min.Order:0

Negotiable

Type:Trading Company

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Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

(S) - N- Boc- adamantylglycine

Cas:361441-97-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Asure Biochem CO.,LTD.

*stable and better quality products*efficient and meticulous servicesAppearance:Powder Storage:Store in dry, cool and ventilated place Package:1kg/tin 5kg/tin 25kg/carton Application:Pharmaceutical raw materials, making injection powder oral agent Tr

(S) - N- Boc- adamantylglycine

Cas:361441-97-6

Min.Order:0

Negotiable

Type:Trading Company

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Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

361441-97-6

Cas:361441-97-6

Min.Order:0

Negotiable

Type:Trading Company

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Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

(S) - N- Boc- adamantylglycine

Cas:361441-97-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

(S) - N- Boc- adamantylglycine

Cas:361441-97-6

Min.Order:0

Negotiable

Type:Trading Company

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LEAP CHEM Co., Ltd.

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP

N-Boc-L-Adamantylglycine

Cas:361441-97-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

HWRK Chem

in store Package:50g Application:Organic Chemicals

(S)-N-Boc-adamantylglycine

Cas:361441-97-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Bide Pharmatech Ltd

Our mission is to provide high-quality and innovative products to our customers. By offering a broad range of products, custom synthesis and personalized services, Bide can help scientists speeding up their research in the chemical and pharmaceutical

(2S)-2-(Adamantan-1-yl)-2-((tert-butoxycarbonyl)amino)acetic acid

Cas:361441-97-6

Min.Order:0

Negotiable

Type:Other

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Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

(2S)-2-(Adamantan-1-yl)-2-((tert-butoxycarbonyl)amino)acetic acid

Cas:361441-97-6

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

HENAN SUNLAKE ENTERPRISE CORPORATION

361441-97-6

Cas:361441-97-6

Min.Order:100 Kilogram

Negotiable

Type:Trading Company

inquiry

Changzhou Extraordinary Pharmatech co.,LTD

Changzhou Extraordinary Pharmatech co., LTD. As a leading chemical manufacturer and supplier in China.DAS authentication is passed.We can provide the popular precursor chemicals, we have our own strong R & D team, have our own laboratories and fa

(alfaS)-alfa-[[(1, 1-dimethylethoxy) carbonyl] amino]-tricyclo [3.3.1.13, 7] decane-1-acetic acid

Cas:361441-97-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shaanxi Mingqi Chemical Co., Ltd

Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers.Our advantages:1, High quality with competitive price:1) Standard:BP/USP/EP/Enterprise standard2) All Purity≥99%3) We are manufacturer a

Manufacturer Direct Sales Low Price n-boc-l-adamantylglycine

Cas:361441-97-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Changzhou Pesan Chemical Co.,Ltd

Strong R&D strength and team We have a R&D team with around 30 R&D personnel.All of our employees have chemical backgrounds and have worked in the chemical industry for many years.Our laboratory can synthesize target products with wei

N-Boc-L-Adamantylglycine Adamantane derivatives CAS NO.361441-97-6

Cas:361441-97-6

Min.Order:1 Kilogram

FOB Price: $1.0 / 9999.0

Type:Other

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ENAO Chemical Co, Limited

For quick quotation, please send us the inquiry include CAS#, Structure, Chemical Name, quantity, purity, as well as any additional specifications you require, we will try to get back to you within 24 hours. Our Services Besides manufacturing,

(2S)-2-(Adamantan-1-yl)-2-((tert-butoxycarbonyl)amino)acetic acid

Cas:361441-97-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HuBei Ipure Biotech CO.,ltd

HuBei ipure is a diversified product production and operation enterprise, with API, pharma intermediates, and other fine chemicals as well as R&D and pigments development and sales as one of the large enterprises, with more than 130 acres of pl

Manufacturer Direct Sales Low Price n-boc-l-adamantylglycine

Cas:361441-97-6

Min.Order:1 Gram

FOB Price: $1.0

Type:Trading Company

inquiry

Synthetic route

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

(S)-(+)-(adamant-1-yl)aminoacetic acid hydrochloride
102502-64-7

(S)-(+)-(adamant-1-yl)aminoacetic acid hydrochloride

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

Conditions
ConditionsYield
With potassium carbonate In DMF (N,N-dimethyl-formamide) at 20℃; for 19h;92%
With triethylamine In methanol80%
Stage #1: (S)-(+)-(adamant-1-yl)aminoacetic acid hydrochloride With sodium hydroxide In water at 0 - 5℃; for 0.25h;
Stage #2: di-tert-butyl dicarbonate In tetrahydrofuran; water at 0 - 5℃;
80 g
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 19h; Inert atmosphere;4.07 g
C17H27NO3

C17H27NO3

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

Conditions
ConditionsYield
With sodium chlorite; potassium dihydrogenphosphate; 2-methyl-but-2-ene In tert-butyl alcohol at 0 - 10℃; for 19.5h;82%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

(S)-(+)-β-amino-1-adamantaneacetic acid
95853-35-3

(S)-(+)-β-amino-1-adamantaneacetic acid

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide for 19h;4.07 g
(S)-2-(adamantan-1-yl)-2-(((R)-2-hydroxy-1-phenylethyl)amino)acetonitrile
361441-95-4

(S)-2-(adamantan-1-yl)-2-(((R)-2-hydroxy-1-phenylethyl)amino)acetonitrile

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 78 percent / aq. HCl; AcOH / 18 h / 80 °C
2: H2; AcOH / Pd(OH)2/C / methanol / 18 h / 2585.74 Torr
3: 4.07 g / K2CO3 / dimethylformamide / 19 h
View Scheme
Multi-step reaction with 3 steps
1: hydrogenchloride; water / acetic acid / 80 °C
2: hydrogen; palladium 10% on activated carbon / acetic acid
3: triethylamine / methanol
View Scheme
Multi-step reaction with 3 steps
1.1: hydrogenchloride; acetic acid; water / 20 - 95 °C
2.1: acetic acid; hydrogen; 10% palladium hydroxide on charcoal / methanol / 20 °C
3.1: sodium hydroxide / water / 0.25 h / 0 - 5 °C
3.2: 0 - 5 °C
View Scheme
Multi-step reaction with 3 steps
1: hydrogenchloride; water / acetic acid / 18 h / 80 °C
2: hydrogen; 20% palladium hydroxide-activated charcoal / methanol; acetic acid / 18 h / 2585.81 Torr
3: potassium carbonate / N,N-dimethyl-formamide / 19 h / 20 °C / Inert atmosphere
View Scheme
(R)-N-((S)-(adamantan-1-yl)(carboxy)methyl)-2-hydroxy-1-phenylethan-1-ammonium chloride

(R)-N-((S)-(adamantan-1-yl)(carboxy)methyl)-2-hydroxy-1-phenylethan-1-ammonium chloride

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: H2; AcOH / Pd(OH)2/C / methanol / 18 h / 2585.74 Torr
2: 4.07 g / K2CO3 / dimethylformamide / 19 h
View Scheme
Multi-step reaction with 2 steps
1: hydrogen; palladium 10% on activated carbon / acetic acid
2: triethylamine / methanol
View Scheme
Multi-step reaction with 2 steps
1.1: acetic acid; hydrogen; 10% palladium hydroxide on charcoal / methanol / 20 °C
2.1: sodium hydroxide / water / 0.25 h / 0 - 5 °C
2.2: 0 - 5 °C
View Scheme
Multi-step reaction with 2 steps
1: hydrogen; 20% palladium hydroxide-activated charcoal / methanol; acetic acid / 18 h / 2585.81 Torr
2: potassium carbonate / N,N-dimethyl-formamide / 19 h / 20 °C / Inert atmosphere
View Scheme
1-adamantanemethanol
770-71-8

1-adamantanemethanol

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 98 percent / oxalyl chloride; DMSO; Et3N / CH2Cl2 / 1 h / -78 °C
2: 65 percent / NaHSO3 / H2O; methanol / 16 h / Heating
3: 78 percent / aq. HCl; AcOH / 18 h / 80 °C
4: H2; AcOH / Pd(OH)2/C / methanol / 18 h / 2585.74 Torr
5: 4.07 g / K2CO3 / dimethylformamide / 19 h
View Scheme
Multi-step reaction with 5 steps
1.1: potassium bromide; sodium hydrogencarbonate / dichloromethane / 0.25 h / 0 - 5 °C
1.2: 0 - 5 °C
2.1: sodium hydrogensulfite / methanol; water / 0 - 55 °C
3.1: hydrogenchloride; acetic acid; water / 20 - 95 °C
4.1: acetic acid; hydrogen; 10% palladium hydroxide on charcoal / methanol / 20 °C
5.1: sodium hydroxide / water / 0.25 h / 0 - 5 °C
5.2: 0 - 5 °C
View Scheme
Multi-step reaction with 5 steps
1.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 1 h / -78 °C / Inert atmosphere
1.2: 0.5 h / -78 °C / Inert atmosphere
2.1: sodium hydrogensulfite / methanol; water / 18 h / 0 - 20 °C / Reflux
3.1: hydrogenchloride; water / acetic acid / 18 h / 80 °C
4.1: hydrogen; 20% palladium hydroxide-activated charcoal / methanol; acetic acid / 18 h / 2585.81 Torr
5.1: potassium carbonate / N,N-dimethyl-formamide / 19 h / 20 °C / Inert atmosphere
View Scheme
1-Adamantanecarboxylic acid
828-51-3

1-Adamantanecarboxylic acid

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: 100 percent / diethyl ether; hexane; methanol / 3 h / 20 °C
2: 96 percent / LiAlH4 / tetrahydrofuran / 1.5 h / 0 - 20 °C
3: 98 percent / oxalyl chloride; DMSO; Et3N / CH2Cl2 / 1 h / -78 °C
4: 65 percent / NaHSO3 / H2O; methanol / 16 h / Heating
5: 78 percent / aq. HCl; AcOH / 18 h / 80 °C
6: H2; AcOH / Pd(OH)2/C / methanol / 18 h / 2585.74 Torr
7: 4.07 g / K2CO3 / dimethylformamide / 19 h
View Scheme
Multi-step reaction with 7 steps
1.1: thionyl chloride / 3 h / 20 °C
2.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 - 20 °C / Inert atmosphere
3.1: potassium bromide; sodium hydrogencarbonate / dichloromethane / 0.25 h / 0 - 5 °C
3.2: 0 - 5 °C
4.1: sodium hydrogensulfite / methanol; water / 0 - 55 °C
5.1: hydrogenchloride; acetic acid; water / 20 - 95 °C
6.1: acetic acid; hydrogen; 10% palladium hydroxide on charcoal / methanol / 20 °C
7.1: sodium hydroxide / water / 0.25 h / 0 - 5 °C
7.2: 0 - 5 °C
View Scheme
Multi-step reaction with 7 steps
1.1: methanol; diethyl ether; hexane / 3 h / 20 °C
2.1: lithium aluminium tetrahydride / tetrahydrofuran / 1.5 h / 20 °C / Inert atmosphere
3.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 1 h / -78 °C / Inert atmosphere
3.2: 0.5 h / -78 °C / Inert atmosphere
4.1: sodium hydrogensulfite / methanol; water / 18 h / 0 - 20 °C / Reflux
5.1: hydrogenchloride; water / acetic acid / 18 h / 80 °C
6.1: hydrogen; 20% palladium hydroxide-activated charcoal / methanol; acetic acid / 18 h / 2585.81 Torr
7.1: potassium carbonate / N,N-dimethyl-formamide / 19 h / 20 °C / Inert atmosphere
View Scheme
1-Adamantanecarbaldehyde
2094-74-8

1-Adamantanecarbaldehyde

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 65 percent / NaHSO3 / H2O; methanol / 16 h / Heating
2: 78 percent / aq. HCl; AcOH / 18 h / 80 °C
3: H2; AcOH / Pd(OH)2/C / methanol / 18 h / 2585.74 Torr
4: 4.07 g / K2CO3 / dimethylformamide / 19 h
View Scheme
Multi-step reaction with 4 steps
1: sodium hydrogensulfite / 0 - 60 °C
2: hydrogenchloride; water / acetic acid / 80 °C
3: hydrogen; palladium 10% on activated carbon / acetic acid
4: triethylamine / methanol
View Scheme
Multi-step reaction with 4 steps
1.1: sodium hydrogensulfite / methanol; water / 0 - 55 °C
2.1: hydrogenchloride; acetic acid; water / 20 - 95 °C
3.1: acetic acid; hydrogen; 10% palladium hydroxide on charcoal / methanol / 20 °C
4.1: sodium hydroxide / water / 0.25 h / 0 - 5 °C
4.2: 0 - 5 °C
View Scheme
Multi-step reaction with 4 steps
1: sodium hydrogensulfite / methanol; water / 18 h / 0 - 20 °C / Reflux
2: hydrogenchloride; water / acetic acid / 18 h / 80 °C
3: hydrogen; 20% palladium hydroxide-activated charcoal / methanol; acetic acid / 18 h / 2585.81 Torr
4: potassium carbonate / N,N-dimethyl-formamide / 19 h / 20 °C / Inert atmosphere
View Scheme
methyl adamantane-1-carboxylate
711-01-3

methyl adamantane-1-carboxylate

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 96 percent / LiAlH4 / tetrahydrofuran / 1.5 h / 0 - 20 °C
2: 98 percent / oxalyl chloride; DMSO; Et3N / CH2Cl2 / 1 h / -78 °C
3: 65 percent / NaHSO3 / H2O; methanol / 16 h / Heating
4: 78 percent / aq. HCl; AcOH / 18 h / 80 °C
5: H2; AcOH / Pd(OH)2/C / methanol / 18 h / 2585.74 Torr
6: 4.07 g / K2CO3 / dimethylformamide / 19 h
View Scheme
Multi-step reaction with 6 steps
1.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 - 20 °C / Inert atmosphere
2.1: potassium bromide; sodium hydrogencarbonate / dichloromethane / 0.25 h / 0 - 5 °C
2.2: 0 - 5 °C
3.1: sodium hydrogensulfite / methanol; water / 0 - 55 °C
4.1: hydrogenchloride; acetic acid; water / 20 - 95 °C
5.1: acetic acid; hydrogen; 10% palladium hydroxide on charcoal / methanol / 20 °C
6.1: sodium hydroxide / water / 0.25 h / 0 - 5 °C
6.2: 0 - 5 °C
View Scheme
Multi-step reaction with 6 steps
1.1: lithium aluminium tetrahydride / tetrahydrofuran / 1.5 h / 20 °C / Inert atmosphere
2.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 1 h / -78 °C / Inert atmosphere
2.2: 0.5 h / -78 °C / Inert atmosphere
3.1: sodium hydrogensulfite / methanol; water / 18 h / 0 - 20 °C / Reflux
4.1: hydrogenchloride; water / acetic acid / 18 h / 80 °C
5.1: hydrogen; 20% palladium hydroxide-activated charcoal / methanol; acetic acid / 18 h / 2585.81 Torr
6.1: potassium carbonate / N,N-dimethyl-formamide / 19 h / 20 °C / Inert atmosphere
View Scheme
L-boroPro-pn

L-boroPro-pn

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

C31H49BN2O5

C31H49BN2O5

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 0 - 20℃;93%
(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

(2S,4S,5S)-4,5-methano-L-proline carboxylamide trifluoroacetate

(2S,4S,5S)-4,5-methano-L-proline carboxylamide trifluoroacetate

[(S)-1-Adamantan-1-yl-2-((1S,3S,5S)-3-carbamoyl-2-aza-bicyclo[3.1.0]hex-2-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester
862784-24-5

[(S)-1-Adamantan-1-yl-2-((1S,3S,5S)-3-carbamoyl-2-aza-bicyclo[3.1.0]hex-2-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With TEA; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃;90%
(S)-1-(((R)-1-amino-5-(benzyloxy)-1,5-dioxopentan-2-yl)amino)-1-oxopropan-2-aminium 2,2,2-trifluoroacetate
66025-93-2

(S)-1-(((R)-1-amino-5-(benzyloxy)-1,5-dioxopentan-2-yl)amino)-1-oxopropan-2-aminium 2,2,2-trifluoroacetate

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

tert-butyloxycarbonyl (S)-2-adamant-1-ylglycyl-L-alanyl-D-isoglutamine benzyl ester

tert-butyloxycarbonyl (S)-2-adamant-1-ylglycyl-L-alanyl-D-isoglutamine benzyl ester

Conditions
ConditionsYield
Stage #1: (alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0℃; for 0.5h;
Stage #2: (S)-1-(((R)-1-amino-5-(benzyloxy)-1,5-dioxopentan-2-yl)amino)-1-oxopropan-2-aminium 2,2,2-trifluoroacetate With triethylamine In 1,4-dioxane; dichloromethane at 0 - 20℃; for 49h;
82%
(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

A

(αS)-α-[[(1,1-dimethylethoxy)carbonyl]-amino]-3-hydroxytricyclo[3.3.1.13,7]decane-1-acetic acid
361442-00-4

(αS)-α-[[(1,1-dimethylethoxy)carbonyl]-amino]-3-hydroxytricyclo[3.3.1.13,7]decane-1-acetic acid

B

(S)-2-((tert-butoxycarbonyl)amino)-2-(3,5-dihydroxyadamantan-1-yl)acetic acid
681282-72-4

(S)-2-((tert-butoxycarbonyl)amino)-2-(3,5-dihydroxyadamantan-1-yl)acetic acid

Conditions
ConditionsYield
With potassium hydroxide; potassium permanganate at 60 - 90℃; for 1.5h;A 51%
B 17%
With potassium hydroxide; potassium permanganate In water at 60 - 90℃; for 1.5h;A 51%
B 17%
(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

(αS)-α-[[(1,1-dimethylethoxy)carbonyl]-amino]-3-hydroxytricyclo[3.3.1.13,7]decane-1-acetic acid
361442-00-4

(αS)-α-[[(1,1-dimethylethoxy)carbonyl]-amino]-3-hydroxytricyclo[3.3.1.13,7]decane-1-acetic acid

Conditions
ConditionsYield
With potassium permanganate; water; potassium hydroxide at 60 - 90℃; for 1.5h;51%
With potassium permanganate; potassium hydroxide at 90℃;49%
With potassium permanganate; tetrabutylammomium bromide; potassium hydroxide In water at 20 - 25℃;18.6 g
C20-O-trityl-prostratin-ol
1262389-74-1

C20-O-trityl-prostratin-ol

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

C56H67NO8

C56H67NO8

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 14h;24.8%
(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

(S)-2-Amino-N4,N4-dimethyl-N1-(3,3,3-trifluoro-2-hydroxy-1-methyl-propyl)-succinamide; hydrochloride

(S)-2-Amino-N4,N4-dimethyl-N1-(3,3,3-trifluoro-2-hydroxy-1-methyl-propyl)-succinamide; hydrochloride

{(S)-Adamantan-1-yl-[(S)-2-dimethylcarbamoyl-1-(3,3,3-trifluoro-2-hydroxy-1-methyl-propylcarbamoyl)-ethylcarbamoyl]-methyl}-carbamic acid tert-butyl ester

{(S)-Adamantan-1-yl-[(S)-2-dimethylcarbamoyl-1-(3,3,3-trifluoro-2-hydroxy-1-methyl-propylcarbamoyl)-ethylcarbamoyl]-methyl}-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane for 2.5h;
L-Alanine methyl ester
10065-72-2

L-Alanine methyl ester

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

(S)-2-((S)-2-Adamantan-1-yl-2-tert-butoxycarbonylamino-acetylamino)-propionic acid methyl ester
882034-92-6

(S)-2-((S)-2-Adamantan-1-yl-2-tert-butoxycarbonylamino-acetylamino)-propionic acid methyl ester

Conditions
ConditionsYield
With 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane
N-(cyanomethyl)ethylamine
24426-40-2

N-(cyanomethyl)ethylamine

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

[adamantan-1-yl-(cyanomethyl-ethyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester

[adamantan-1-yl-(cyanomethyl-ethyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane
N-propene-2 aminoacetonitrile
54243-43-5

N-propene-2 aminoacetonitrile

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

[adamantan-1-yl-(allyl-cyanomethyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester

[adamantan-1-yl-(allyl-cyanomethyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane
propylamino acetonitrile
16728-81-7

propylamino acetonitrile

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

[adamantan-1-yl-(cyanomethyl-propyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester

[adamantan-1-yl-(cyanomethyl-propyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane
2-amino-2-methylpropionic acid methyl ester
13257-67-5

2-amino-2-methylpropionic acid methyl ester

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

2-(2-adamantan-1-yl-2-tert-butoxycarbonylamino-acetylamino)-2-methyl-propionic acid methyl ester
882034-93-7

2-(2-adamantan-1-yl-2-tert-butoxycarbonylamino-acetylamino)-2-methyl-propionic acid methyl ester

Conditions
ConditionsYield
With 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane
benzylaminoacetonitrile
3010-05-7

benzylaminoacetonitrile

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

[adamantan-1-yl-(benzyl-cyanomethyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester

[adamantan-1-yl-(benzyl-cyanomethyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane
(cyclopropylamino)acetonitrile
30858-68-5

(cyclopropylamino)acetonitrile

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

[adamantan-1-yl-(cyanomethyl-cyclopropyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester

[adamantan-1-yl-(cyanomethyl-cyclopropyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane
2-aminoacetonitrile
540-61-4

2-aminoacetonitrile

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

[adamantan-1-yl-(cyanomethyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester

[adamantan-1-yl-(cyanomethyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane
(methylamino)acetonitrile
5616-32-0

(methylamino)acetonitrile

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

[adamantan-1-yl-(cyanomethyl-methyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester

[adamantan-1-yl-(cyanomethyl-methyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane
(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

2-adamantan-1-yl-2-amino-N-cyanomethyl-acetamide

2-adamantan-1-yl-2-amino-N-cyanomethyl-acetamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: EDAC; HOAt; Et3N / CH2Cl2
2: TFA / CH2Cl2
View Scheme
(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

2-adamantan-1-yl-2-amino-N-cyanomethyl-N-methyl-acetamide

2-adamantan-1-yl-2-amino-N-cyanomethyl-N-methyl-acetamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: EDAC; HOAt; Et3N / CH2Cl2
2: TFA / CH2Cl2
View Scheme
(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

(S)-2-Adamantan-1-yl-2-amino-N-((S)-cyano-methyl-methyl)-acetamide

(S)-2-Adamantan-1-yl-2-amino-N-((S)-cyano-methyl-methyl)-acetamide

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: EDAC; HOAt; Et3N / CH2Cl2
2: aq. NaOH / methanol / 50 °C
3: NMO; i-BuOCOCl; NH3 / -15 °C
4: TFAA / CH2Cl2
5: TFA / CH2Cl2
View Scheme
(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

2-adamantan-1-yl-2-amino-N-(cyano-dimethyl-methyl)-acetamide

2-adamantan-1-yl-2-amino-N-(cyano-dimethyl-methyl)-acetamide

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: EDAC; HOAt; Et3N / CH2Cl2
2: aq. NaOH / methanol / 50 °C
3: NMO; i-BuOCOCl; NH3 / -15 °C
4: TFAA / CH2Cl2
5: TFA / CH2Cl2
View Scheme
(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

2-adamantan-1-yl-2-amino-N-cyanomethyl-N-ethyl-acetamide

2-adamantan-1-yl-2-amino-N-cyanomethyl-N-ethyl-acetamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: EDAC; HOAt; Et3N / CH2Cl2
2: TFA / CH2Cl2
View Scheme
(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

2-adamantan-1-yl-2-amino-N-cyanomethyl-N-cyclopropyl-acetamide

2-adamantan-1-yl-2-amino-N-cyanomethyl-N-cyclopropyl-acetamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: EDAC; HOAt; Et3N / CH2Cl2
2: TFA / CH2Cl2
View Scheme
(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

2-adamantan-1-yl-2-amino-N-cyanomethyl-N-propyl-acetamide

2-adamantan-1-yl-2-amino-N-cyanomethyl-N-propyl-acetamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: EDAC; HOAt; Et3N / CH2Cl2
2: TFA / CH2Cl2
View Scheme
(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

2-adamantan-1-yl-N-allyl-2-amino-N-cyanomethyl-acetamide

2-adamantan-1-yl-N-allyl-2-amino-N-cyanomethyl-acetamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: EDAC; HOAt; Et3N / CH2Cl2
2: TFA / CH2Cl2
View Scheme
(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

2-adamantan-1-yl-2-amino-N-benzyl-N-cyanomethyl-acetamide

2-adamantan-1-yl-2-amino-N-benzyl-N-cyanomethyl-acetamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: EDAC; HOAt; Et3N / CH2Cl2
2: TFA / CH2Cl2
View Scheme
(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

{adamantan-1-yl-[(cyano-dimethyl-methyl)-carbamoyl]-methyl}-carbamic acid tert-butyl ester

{adamantan-1-yl-[(cyano-dimethyl-methyl)-carbamoyl]-methyl}-carbamic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: EDAC; HOAt; Et3N / CH2Cl2
2: aq. NaOH / methanol / 50 °C
3: NMO; i-BuOCOCl; NH3 / -15 °C
4: TFAA / CH2Cl2
View Scheme
(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid
361441-97-6

(alpha S)-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]tricyclo[3.3.1.13,7]decane-1-acetic acid

{(S)-Adamantan-1-yl-[((S)-cyano-methyl-methyl)-carbamoyl]-methyl}-carbamic acid tert-butyl ester

{(S)-Adamantan-1-yl-[((S)-cyano-methyl-methyl)-carbamoyl]-methyl}-carbamic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: EDAC; HOAt; Et3N / CH2Cl2
2: aq. NaOH / methanol / 50 °C
3: NMO; i-BuOCOCl; NH3 / -15 °C
4: TFAA / CH2Cl2
View Scheme

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