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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Suberic acid monomethyl ester Manufacturer/High quality/Best price/In stock

Cas:3946-32-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay (Ursolic acid) 98%min 98.22% ----------------------------------------------------------------

High purity 3946-32-5 Suberic acid monomethyl ester

Cas:3946-32-5

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Trading Company

inquiry

Henan Allgreen Chemical Co.,Ltd

Good quality Good price Promptly delivery Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:intermediate Transportation:Ac

3946-32-5SUBERIC ACID MONOMETHYL ESTER

Cas:3946-32-5

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Suberic acid monomethyl ester

Cas:3946-32-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. High quality and competitive price: 1) Standard: BP/USP/EP/ enterprise standard 2) All purity ≥99% 3) We are manufacturers and can provide high quality products at factory prices. 2. Fast and safe delivery 1) The package c

SUBERIC ACID MONOMETHYL ESTER CAS 3946-32-5

Cas:3946-32-5

Min.Order:1 Kilogram

FOB Price: $5.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 3946-32-5 with best quality

Cas:3946-32-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Monomethyl Suberate English Name: Monomethyl Suberate Formula: C9H16O4 Purity: 98% CAS: 3946-32-5 Melting Point(οC): 21 Usage: Intermediate Appearance:White powder or crystal Storage:RT Package:on request Application:Intermediat

3946-32-5 Monomethyl Suberate

Cas:3946-32-5

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Octanedioic acid,1-methyl ester 3946-32-5

Cas:3946-32-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

Name: Octanedioic acid,1-methyl ester Synonyms: Monomethyl suberate; Methyl1,8-octanedionate; Methyl 7-carboxyheptanoate; 8-Methoxy-8-oxooctanoic acid; Subericacid, monomethyl ester (8CI); Suberic acid, methyl ester (6CI,7CI); Octanedioicacid, monome

8-methoxy-8-oxooctanoic acid 3946-32-5

Cas:3946-32-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:3946-32-5

Cas:3946-32-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

SUBERIC ACID MONOMETHYL ESTER

Cas:3946-32-5

Min.Order:1 Kilogram

FOB Price: $40.0 / 50.0

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Monomethyl Suberate

Cas:3946-32-5

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Monomethyl Suberate

Cas:3946-32-5

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

Monomethyl Suberate

Cas:3946-32-5

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

3946-32-5 SUBERIC ACID MONOMETHYL ESTER

Cas:3946-32-5

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Suberic acid monomethyl ester

Cas:3946-32-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: SUBERIC ACID MONOMETHYL ESTER Synonyms: METHYL HYDROGEN SUBERATE;METHYL HYDROGEN OCTANE-1,8-DIOATE;SUBERIC ACID MONOMETHYL ESTER;OCTANEDIOIC ACID MONOMETHYL ESTER;MONOMETHYL OCTANE-1,8-DIOATE;MONOMETHYL SUBERATE;SUBERIC ACID METHYL E

SUBERIC ACID MONOMETHYL ESTER 3946-32-5 large in supply

Cas:3946-32-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Monomethyl Suberate

Cas:3946-32-5

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Monomethyl Suberate

Cas:3946-32-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Monomethyl Suberate

Cas:3946-32-5

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Subericacidmonomethylester

Cas:3946-32-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Shanghai Massive Chemical Technology Co., Ltd. is engaged in development, production and marketing Specialty Chemicals to satisfy the changing needs of the chemical industry. We specialize in manufacturing high quality of Advanced Intermediates, Sp

Monomethyl octanedioate

Cas:3946-32-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

Suberic acid monomethyl ester

Cas:3946-32-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

Monomethyl Suberate

Cas:3946-32-5

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

SUBERIC ACID MONOMETHYL ESTER cas no. 3946-32-5 98%

Cas:3946-32-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

Suberic acid monomethyl ester

Cas:3946-32-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

Suberic Acid Monomethyl Ester

Cas:3946-32-5

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec Suberic acid monomethyl ester 100g

Cas:3946-32-5

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

Suberic acid monomethyl ester

Cas:3946-32-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Suberic acid MonoMethyl ester

Cas:3946-32-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

dimethyl subarate
1732-09-8

dimethyl subarate

suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

Conditions
ConditionsYield
With porcine liver esterase; sodium hydroxide; phosphate buffer for 6h;87%
With sodium hydroxide; phosphate buffer for 1h; Ambient temperature; pig liver esterase;87%
With sodium hydroxide; porcine pancreatic lipase In water Hydrolysis; Enzymatic reaction; pH 7;85%
methanol
67-56-1

methanol

oxonane-2,9-dione
10521-06-9

oxonane-2,9-dione

suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

Conditions
ConditionsYield
for 3h; Reflux;80%
methanol
67-56-1

methanol

octane-1,8-dioic acid
505-48-6

octane-1,8-dioic acid

A

suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

B

dimethyl subarate
1732-09-8

dimethyl subarate

Conditions
ConditionsYield
With aluminum oxide at 25℃; for 48h; Green chemistry; chemoselective reaction;A 72%
B 11%
With sulfuric acid
methanol
67-56-1

methanol

octane-1,8-dioic acid
505-48-6

octane-1,8-dioic acid

suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

Conditions
ConditionsYield
With acid33%
With hydrogenchloride; water
With boron trifluoride methanol complex for 0.5h; Heating;
octane-1,8-dioic acid
505-48-6

octane-1,8-dioic acid

dimethyl subarate
1732-09-8

dimethyl subarate

suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

Conditions
ConditionsYield
With hydrogenchloride; dibutyl ether at 170℃;
octane-1,8-dioic acid
505-48-6

octane-1,8-dioic acid

suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

Conditions
ConditionsYield
With aluminum oxide In cyclohexane; N,N-dimethyl-formamide Product distribution; study of selectivity of methylation on alumina surface;
octane-1,8-dioic acid
505-48-6

octane-1,8-dioic acid

dimethyl sulfate
77-78-1

dimethyl sulfate

suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

Conditions
ConditionsYield
aluminum oxide In cyclohexane for 2h; Heating; Yield given;
methanol
67-56-1

methanol

2-nitrocyclooctanone
13154-28-4

2-nitrocyclooctanone

suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

Conditions
ConditionsYield
With Oxone; potassium hydroxide; sodium hydroxide; disodium hydrogenphosphate; water 1.) 65 deg C, 4 h, 2.) r.t., 4 h; Yield given. Multistep reaction;
octane-1,8-dioic acid
505-48-6

octane-1,8-dioic acid

suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 90 percent / H2SO4 / Heating
2: 34 percent / KOH / methanol / 4 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: Me3SiCl / methanol / 24 h / 20 °C
2: 85 percent / porcine pancreatic lipase; NaOH / H2O / Enzymatic reaction; pH 7
View Scheme
Multi-step reaction with 2 steps
1: sulfuric acid / methanol / 12 h
2: potassium hydroxide / methanol / 4 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: acetic anhydride / Heating
2: 3 h / Reflux
View Scheme
dimethyl subarate
1732-09-8

dimethyl subarate

A

heptanedioic acid
111-16-0

heptanedioic acid

B

octane-1,8-dioic acid
505-48-6

octane-1,8-dioic acid

C

suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

Conditions
ConditionsYield
With Amberlyst 35 In water; acetic acid at 95℃; for 20h; Inert atmosphere; Overall yield = 0.41 g;A 0.34 %Chromat.
B 88.58%Chromat.
C 10.6 %Chromat.
suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

(3-aminophenyl)carbamic acid tert-butyl ester
68621-88-5

(3-aminophenyl)carbamic acid tert-butyl ester

7-(3-(tert-butoxycarbonylamino)phenylcarbamoyl)heptanoic acid methyl ester
1204005-96-8

7-(3-(tert-butoxycarbonylamino)phenylcarbamoyl)heptanoic acid methyl ester

Conditions
ConditionsYield
Stage #1: suberic acid monomethyl ester With 4-methyl-morpholine; chloroformic acid ethyl ester In dichloromethane at 0℃; for 0.25h;
Stage #2: (3-aminophenyl)carbamic acid tert-butyl ester In dichloromethane at 20℃;
100%
With pyridine; trichlorophosphate at 0℃;46%
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 12h;
suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

C8H3NO3Re

C8H3NO3Re

tricarbonyl{methyl 8-[(η5-cyclopentadienyl)amino]-8-oxooctanoate}rhenium

tricarbonyl{methyl 8-[(η5-cyclopentadienyl)amino]-8-oxooctanoate}rhenium

Conditions
ConditionsYield
With 4-methyl-morpholine; isobutyl chloroformate In tetrahydrofuran at 20℃; for 17h; Inert atmosphere;100%
suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

C8H3MnNO3

C8H3MnNO3

tricarbonyl{methyl 8-[(η5-cyclopentadienyl)amino]-8-oxooctanoate}manganese

tricarbonyl{methyl 8-[(η5-cyclopentadienyl)amino]-8-oxooctanoate}manganese

Conditions
ConditionsYield
With 4-methyl-morpholine; isobutyl chloroformate In tetrahydrofuran at 20℃; for 17h; Inert atmosphere;100%
suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

N-(tert-butoxycarbonyl)-1,4-phenylenediamine
71026-66-9

N-(tert-butoxycarbonyl)-1,4-phenylenediamine

chloroformic acid ethyl ester
541-41-3

chloroformic acid ethyl ester

methyl 8-((4-((tert-butoxycarbonyl)amino)phenyl)amino)-8-oxooctanoate

methyl 8-((4-((tert-butoxycarbonyl)amino)phenyl)amino)-8-oxooctanoate

Conditions
ConditionsYield
Stage #1: suberic acid monomethyl ester; chloroformic acid ethyl ester With 4-methyl-morpholine In dichloromethane at 20℃; for 0.166667h; Inert atmosphere;
Stage #2: N-(tert-butoxycarbonyl)-1,4-phenylenediamine In dichloromethane at 20℃; Inert atmosphere;
99%
suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

2,3-dihydro-5-methoxy-1H-inden-1-amine
52372-95-9

2,3-dihydro-5-methoxy-1H-inden-1-amine

methyl 8-((5-methoxy-2,3-dihydro-1H-inden-1-yl)amino)-8-oxooctanoate

methyl 8-((5-methoxy-2,3-dihydro-1H-inden-1-yl)amino)-8-oxooctanoate

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃;99%
suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

6-methoxy-1-amino-1,2,3,4-tetrahydronaphthalene
52373-02-1

6-methoxy-1-amino-1,2,3,4-tetrahydronaphthalene

methyl 8-((6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)amino)-8-oxooctanoate

methyl 8-((6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)amino)-8-oxooctanoate

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 0 - 20℃;99%
5-bromo-2,3-dihydro-1H-inden-1-one oxime
185122-74-1

5-bromo-2,3-dihydro-1H-inden-1-one oxime

suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

methyl 8-((5-bromo-2,3-dihydro-1H-inden-1-yl)amino)-8-oxooctanoate

methyl 8-((5-bromo-2,3-dihydro-1H-inden-1-yl)amino)-8-oxooctanoate

Conditions
ConditionsYield
With 4-methyl-morpholine; dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃;99%
suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

8-hydroxyoctanoic acid methyl ester
20257-95-8

8-hydroxyoctanoic acid methyl ester

Conditions
ConditionsYield
With borane-THF In tetrahydrofuran for 12h; Ambient temperature;98%
With borane-THF In tetrahydrofuran at -15 - 20℃; for 24h;90%
suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

aniline
62-53-3

aniline

7-phenylcarbamoyl heptanoic acid methyl ester
162853-41-0

7-phenylcarbamoyl heptanoic acid methyl ester

Conditions
ConditionsYield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; diisopropylamine In dichloromethane at 20℃; for 12h;98%
Stage #1: suberic acid monomethyl ester; aniline With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide for 0.0833333h;
Stage #2: With benzotriazol-1-ol at 25℃; for 4h;
94%
With benzotriazol-1-ol; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 20℃; for 1.5h;88.7%
PD 0332991
571190-30-2

PD 0332991

suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

methyl 8-(4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-8-oxooctanoate

methyl 8-(4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-8-oxooctanoate

Conditions
ConditionsYield
With 4-methyl-morpholine; 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane; N,N-dimethyl-formamide at 20℃;98%
suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

tert–butyl (2–aminophenyl)carbamate
146651-75-4

tert–butyl (2–aminophenyl)carbamate

methyl 8-((2-((tert–butoxycarbonyl)amino)phenyl)amino)-8–oxooctanoate

methyl 8-((2-((tert–butoxycarbonyl)amino)phenyl)amino)-8–oxooctanoate

Conditions
ConditionsYield
Stage #1: suberic acid monomethyl ester With dmap; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In chloroform at 20℃; for 0.5h; Inert atmosphere;
Stage #2: tert–butyl (2–aminophenyl)carbamate In chloroform at 20℃; Inert atmosphere;
98%
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 12h;
suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

N-demethyltamoxifen
31750-47-7, 31750-48-8

N-demethyltamoxifen

methyl (Z)-8-((2-(4-(1,2-diphenylbut-1-en-1-yl)phenoxy)ethyl)(methyl)amino)-8-oxooctanoate

methyl (Z)-8-((2-(4-(1,2-diphenylbut-1-en-1-yl)phenoxy)ethyl)(methyl)amino)-8-oxooctanoate

Conditions
ConditionsYield
With 4-methyl-morpholine; 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃;97%
oxalyl dichloride
79-37-8

oxalyl dichloride

suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

methyl 8-chloro-8-oxooctanoate
41624-92-4

methyl 8-chloro-8-oxooctanoate

Conditions
ConditionsYield
With N,N-dimethyl-formamide In benzene 1.) 5 deg C, 15 min; 2.) 23 deg C, 2 h; 3.) 60 deg C, 1 h;96%
suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

O-benzylhydoxylamine hydrochloride
2687-43-6

O-benzylhydoxylamine hydrochloride

methyl N-benzyloxysuberoylamide
149648-49-7

methyl N-benzyloxysuberoylamide

Conditions
ConditionsYield
With bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; triethylamine In dichloromethane Substitution;95%
With bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; N-ethyl-N,N-diisopropylamine In dichloromethane95%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 4h; Inert atmosphere;
suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

4-methoxy-aniline
104-94-9

4-methoxy-aniline

9-fluorenyl hydroxy(methyl)carbamate
190656-07-6

9-fluorenyl hydroxy(methyl)carbamate

octanedioic acid hydroxy-methyl-amide (4-methoxy-phenyl)-amide

octanedioic acid hydroxy-methyl-amide (4-methoxy-phenyl)-amide

Conditions
ConditionsYield
Multistep reaction.;94%
suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

1-((2S,4S,5S)-4-(2-(4-aminophenyl)-1,3-dithian-2-yl)-5-(((tert-butyldimethylsilyl)oxy)methyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

1-((2S,4S,5S)-4-(2-(4-aminophenyl)-1,3-dithian-2-yl)-5-(((tert-butyldimethylsilyl)oxy)methyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

methyl 8-((4-(2-((2S,3S,5S)-2-(((tert-butyldimethylsilyl)oxy)methyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)-1,3-dithian-2-yl)phenyl)amino)-8-oxooctanoate

methyl 8-((4-(2-((2S,3S,5S)-2-(((tert-butyldimethylsilyl)oxy)methyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)-1,3-dithian-2-yl)phenyl)amino)-8-oxooctanoate

Conditions
ConditionsYield
Stage #1: suberic acid monomethyl ester With bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; N-ethyl-N,N-diisopropylamine In dichloromethane Inert atmosphere;
Stage #2: 1-((2S,4S,5S)-4-(2-(4-aminophenyl)-1,3-dithian-2-yl)-5-(((tert-butyldimethylsilyl)oxy)methyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione In dichloromethane at 20℃; Inert atmosphere;
94%
suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

4-hydroxy-6-methyl-2-pyrone

4-hydroxy-6-methyl-2-pyrone

C15H20O6
1402994-11-9

C15H20O6

Conditions
ConditionsYield
With dmap; diisopropyl-carbodiimide In toluene at 20 - 100℃; for 9h; Inert atmosphere;93%
suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

3-α-acetoxy-4-β-amino-24-norurs-12-ene
108015-89-0

3-α-acetoxy-4-β-amino-24-norurs-12-ene

methyl 8-((3-α-acetoxy-24-norurs-12-en-4-yl)amino)-8-oxooctanoate

methyl 8-((3-α-acetoxy-24-norurs-12-en-4-yl)amino)-8-oxooctanoate

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In tetrahydrofuran at 0 - 20℃; for 16.5h;93%
suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

N-benzyl-N-methoxyamine
20056-98-8

N-benzyl-N-methoxyamine

C17H25NO4

C17H25NO4

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 20℃; for 14h; Inert atmosphere;93%
(4-aminobenzyl)(methyl)carbamic acid tert-butyl ester
225240-83-5

(4-aminobenzyl)(methyl)carbamic acid tert-butyl ester

suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

methyl 8-((4-(((tert-butoxycarbonyl)(methyl)amino)methyl)phenyl)amino)-8-oxooctanoate

methyl 8-((4-(((tert-butoxycarbonyl)(methyl)amino)methyl)phenyl)amino)-8-oxooctanoate

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; for 5h;93%
furan
110-00-9

furan

suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

sodium carbonate
497-19-8

sodium carbonate

Chloroacetic anhydride
541-88-8

Chloroacetic anhydride

8-(furan-2-yl)-8-oxooctanoic acid methyl ester
38199-47-2

8-(furan-2-yl)-8-oxooctanoic acid methyl ester

Conditions
ConditionsYield
In toluene92.3%
suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

tert-butyl N-(6-aminohexyl)carbamate
51857-17-1

tert-butyl N-(6-aminohexyl)carbamate

methyl 8-((6-((tert-butoxycarbonyl)amino)hexyl)amino)-8-oxooctanoate

methyl 8-((6-((tert-butoxycarbonyl)amino)hexyl)amino)-8-oxooctanoate

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 1h;92%
suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

methyl 8-chloro-8-oxooctanoate
41624-92-4

methyl 8-chloro-8-oxooctanoate

Conditions
ConditionsYield
With thionyl chloride for 6h; Heating;91%
With thionyl chloride90%
With oxalyl dichloride; N,N-dimethyl-formamide In toluene at 5 - 20℃; for 1.5h;90%
suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

2-Amino-1-phenylethanol
7568-93-6

2-Amino-1-phenylethanol

7-(2-hydroxy-2-phenyl-ethylcarbamoyl)-heptanoic acid methyl ester
406726-57-6

7-(2-hydroxy-2-phenyl-ethylcarbamoyl)-heptanoic acid methyl ester

Conditions
ConditionsYield
With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide In tetrahydrofuran at 20℃; for 12h;91%
suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

Chloroacetic anhydride
541-88-8

Chloroacetic anhydride

8-oxo-8-thiophen-2-yl-octanoic acid methyl ester
93568-18-4

8-oxo-8-thiophen-2-yl-octanoic acid methyl ester

Conditions
ConditionsYield
In thiophene; 1,1-dichloroethane91%
O-(1-isobutoxyethyl)hydroxylamine
860216-27-9

O-(1-isobutoxyethyl)hydroxylamine

suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

7-(1-isobutoxy-ethoxycarbamoyl)-heptanoic acid methyl ester
914605-61-1

7-(1-isobutoxy-ethoxycarbamoyl)-heptanoic acid methyl ester

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In tetrahydrofuran; dichloromethane at 20℃;91%
suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

Ethyl hydrogen suberate
14113-01-0

Ethyl hydrogen suberate

4-Aminobiphenyl
92-67-1

4-Aminobiphenyl

7-(Biphenyl-4-ylcarbamoyl)-heptanoic acid ethyl ester
406726-68-9

7-(Biphenyl-4-ylcarbamoyl)-heptanoic acid ethyl ester

Conditions
ConditionsYield
91%
3-α-o-acetoxy-4β-amino-11-oxo-24-norurs-12-ene
872090-58-9

3-α-o-acetoxy-4β-amino-11-oxo-24-norurs-12-ene

suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

methyl 8-((3-α-acetoxy-11-oxo-24-norurs-12-en-4-yl)amino)-8-oxooctanoate

methyl 8-((3-α-acetoxy-11-oxo-24-norurs-12-en-4-yl)amino)-8-oxooctanoate

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In tetrahydrofuran at 0 - 20℃; for 16.5h;91%
suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

di-tert-butyl 2-(4-aminophenyl)malonate
1006950-20-4

di-tert-butyl 2-(4-aminophenyl)malonate

di-tert-butyl 2-(4-(8-methoxy-8-oxooctanamido)phenyl)malonate
1350650-29-1

di-tert-butyl 2-(4-(8-methoxy-8-oxooctanamido)phenyl)malonate

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 16h; Cooling with ice;90.1%
2-amino-1-(2-methoxyphenyl)ethan-1-one hydrochloride
34589-97-4

2-amino-1-(2-methoxyphenyl)ethan-1-one hydrochloride

suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

7-[2-(2-methoxyphenyl)-2-oxoethylcarbamoyl]heptanoic acid methyl ester
847266-96-0

7-[2-(2-methoxyphenyl)-2-oxoethylcarbamoyl]heptanoic acid methyl ester

Conditions
ConditionsYield
Stage #1: 2-amino-1-(2-methoxyphenyl)ethan-1-one hydrochloride; suberic acid monomethyl ester With triethylamine In dichloromethane at 0℃;
Stage #2: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 22h;
88%

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