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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

5-(1-Methyl-4-Piperidyl)5H-Dibenzo

Cas:3967-32-6

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

5H-Dibenzo[a,d]cyclohepten-5-ol,5-(1-methyl-4-piperidinyl)- 3967-32-6

Cas:3967-32-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

5-(1-Methyl-4-Piperidyl)5H-Dibenzo CAS:3967-32-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality

5-(1-Methyl-4-Piperidyl)5H-Dibenzo CAS:3967-32-6

Cas:3967-32-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

5H-Dibenzo[a,d]cyclohepten-5-ol,5-(1-methyl-4-piperidinyl)-

Cas:3967-32-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

5H-Dibenzo[a,d]cyclohepten-5-ol,5-(1-methyl-4-piperidinyl)-

Cas:3967-32-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

5H-Dibenzo[a,d]cyclohepten-5-ol,5-(1-methyl-4-piperidinyl)- factory

Cas:3967-32-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

5-(1-METHYL-PIPERIDIN-4-YL)5H-DIBENZO

Cas:3967-32-6

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

5-(1-METHYL-PIPERIDIN-4-YL)5H-DIBENZO

Cas:3967-32-6

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

5-(1-Methyl-4-Piperidyl)5H-Dibenzo

Cas:3967-32-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

5-(1-METHYL-PIPERIDIN-4-YL)5H-DIBENZO

Cas:3967-32-6

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Business Custom Synthesis:

5-(1-Methyl-4-Piperidyl)5H-Dibenzo

Cas:3967-32-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

5-(1-METHYL-PIPERIDIN-4-YL)5H-DIBENZO

Cas:3967-32-6

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Hebei Mojin Biotechnology Co.,Ltd

1, High quality with competitive price:2, Fast and safe delivery3.Excellent pre-sales and after-sales service4. Well-trained and professional technologist and sales with rich experience in the field for 5-10 yearsAppearance:see detailed specification

5H-Dibenzo[a,d]cyclohepten-5-ol,5-(1-methyl-4-piperidinyl)-

Cas:3967-32-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

5H-Dibenzo[a,d]cyclohepten-5-ol,5-(1-methyl-4-piperidinyl)-

Cas:3967-32-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates

5H-Dibenzo[a,d]cyclohepten-5-ol,5-(1-methyl-4-piperidinyl)-

Cas:3967-32-6

Min.Order:0

Negotiable

Type:Trading Company

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals

5-(1-Methyl-4-Piperidyl)5H-Dibenzo

Cas:3967-32-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

5H-Dibenzo[a,d]cyclohepten-5-ol,5-(1-methyl-4-piperidinyl)-

Cas:3967-32-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

5-(1-Methyl-4-Piperidyl)5H-Dibenzo

Cas:3967-32-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

5H-Dibenzo[a,d]cyclohepten-5-ol,5-(1-methyl-4-piperidinyl)-

Cas:3967-32-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

5-(1-METHYL-PIPERIDIN-4-YL)5H-DIBENZO Application:5-(1-METHYL-PIPERIDIN-4-YL)5H-DIBENZO

5-(1-METHYL-PIPERIDIN-4-YL)5H-DIBENZO

Cas:3967-32-6

Min.Order:0

Negotiable

Type:Other

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Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

5-(1-Methyl-4-Piperidyl)5H-Dibenzo CAS No.3967-32-6

Cas:3967-32-6

Min.Order:0

Negotiable

Type:Trading Company

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Wuhan Circle Star Chem-medical Technology co.,Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:White to Off-White Solid Storage:Keep it in dry,shady and cool place Package:as your requirement Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by Sea

5-(1-Methyl-4-Piperidyl)5H-Dibenzo

Cas:3967-32-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

DB BIOTECH CO., LTD

best seller Application:API

5-(1-Methyl-4-Piperidyl)5H-Dibenzo

Cas:3967-32-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Wuhan ZeShanCheng Biomedical Technology Co., Ltd.

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highl

5H-Dibenzo[a,d]cyclohepten-5-ol,5-(1-methyl-4-piperidinyl)-

Cas:3967-32-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

5-(1-Methyl-4-Piperidyl)5H-Dibenzo

Cas:3967-32-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers2. Produce products of different specifications and sizes according to your requirements.3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures sta

5-(1-Methyl-4-Piperidyl)5H-Dibenzo

Cas:3967-32-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou ZeErRui Chemical Co., Ltd.

Hangzhou ZeErRui Chemical Co., Ltd. is focused on customization, research and development and production of APIs and advanced intermediates, which can effectively compensate for the deficiencies of traditional CRO and CMO. Priority of high-tech barri

5-(1-METHYL-PIPERIDIN-4-YL)5H-DIBENZO

Cas:3967-32-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Newgreat Chemical Co., Ltd

Wuhan Xinweiye Chemical Co., Ltd. is mainly engaged in the process development and production of customized synthesis and pharmaceutical intermediates. We have professional researchers in organic synthesis, analytical chemistry and production process

5-(1-METHYL-PIPERIDIN-4-YL)5H-DIBENZO

Cas:3967-32-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hunan Longxianng Runhui Trading Co.,Ltd

5-(1-METHYL-PIPERIDIN-4-YL)5H-DIBENZOAppearance:white crystalline powder Storage:Shading, sealed, dry place. Package:aluminous bag Application:API Transportation:By express (Door to door) such as FEDEX, DHL, EMS for small amount. By air(airport to ai

5-(1-METHYL-PIPERIDIN-4-YL)5H-DIBENZO

Cas:3967-32-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Synthetic route

4-chloro-1-methylpiperidine
5570-77-4

4-chloro-1-methylpiperidine

dibenzosuberenon
2222-33-5

dibenzosuberenon

5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol
3967-32-6

5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol

Conditions
ConditionsYield
Stage #1: 4-chloro-1-methylpiperidine With iodine; magnesium In tetrahydrofuran for 5h; Reflux; Inert atmosphere;
Stage #2: With (trimethylsilyl)methylmagnesium chloride; lithium chloride; zinc(II) chloride In tetrahydrofuran; diethyl ether at 20℃; for 0.75h; Inert atmosphere;
Stage #3: dibenzosuberenon In tetrahydrofuran; diethyl ether at 0℃; for 2h; Inert atmosphere;
99%
Stage #1: 4-chloro-1-methylpiperidine With magnesium In tetrahydrofuran at 60 - 65℃; for 1h; Inert atmosphere; Large scale;
Stage #2: dibenzosuberenon In tetrahydrofuran at 5 - 20℃; for 1h; Temperature; Inert atmosphere; Large scale;
(1-methyl-4-piperidyl)magnesium chloride
63463-36-5

(1-methyl-4-piperidyl)magnesium chloride

dibenzosuberenon
2222-33-5

dibenzosuberenon

5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol
3967-32-6

5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol

Conditions
ConditionsYield
In tetrahydrofuran at 70℃;76%
5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol
3967-32-6

5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol

cyproheptadine
129-03-3

cyproheptadine

Conditions
ConditionsYield
With formic acid at 100℃; for 2h;99%
With hydrogenchloride; acetic acid at 120℃; for 2h;83%
With formic acid for 1h; Heating; Yield given;
5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol
3967-32-6

5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol

(+/-)-(5H)-1-methyl-4-(5H-dibenzocyclohepten-5-yl)piperidine
3973-59-9

(+/-)-(5H)-1-methyl-4-(5H-dibenzocyclohepten-5-yl)piperidine

Conditions
ConditionsYield
With triethylsilane; boron trifluoride In dichloromethane at 0℃; for 3h;74%
5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol
3967-32-6

5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol

4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)piperidine
14051-46-8

4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)piperidine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 83 percent / HOAc, conc. HCl / 2 h / 120 °C
2: Na2CO3 / 1,2-dichloro-ethane / 1) 0 deg C, 2) reflux
3: 1) CH3OH, 2) NaOH / 1) r.t., 15 min, 50 deg C, 15 min, 2) water
View Scheme
5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol
3967-32-6

5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol

4-(4-Dibenzo[a,d]cyclohepten-5-ylidene-piperidin-1-yl)-butylamine
175692-31-6

4-(4-Dibenzo[a,d]cyclohepten-5-ylidene-piperidin-1-yl)-butylamine

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 83 percent / HOAc, conc. HCl / 2 h / 120 °C
2: Na2CO3 / 1,2-dichloro-ethane / 1) 0 deg C, 2) reflux
3: 1) CH3OH, 2) NaOH / 1) r.t., 15 min, 50 deg C, 15 min, 2) water
4: 80 percent / Na2CO3, KI / acetonitrile; dimethylformamide / Heating
5: 62 percent / LiAlH4 / tetrahydrofuran; diethyl ether / 2 h / Ambient temperature
View Scheme
5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol
3967-32-6

5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol

4-<4-(5H-dibenzocyclohepten-5-ylidene)piperidino>butanonitrile
141840-85-9

4-<4-(5H-dibenzocyclohepten-5-ylidene)piperidino>butanonitrile

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 83 percent / HOAc, conc. HCl / 2 h / 120 °C
2: Na2CO3 / 1,2-dichloro-ethane / 1) 0 deg C, 2) reflux
3: 1) CH3OH, 2) NaOH / 1) r.t., 15 min, 50 deg C, 15 min, 2) water
4: 80 percent / Na2CO3, KI / acetonitrile; dimethylformamide / Heating
View Scheme
5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol
3967-32-6

5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol

7-(4-Dibenzo[a,d]cyclohepten-5-ylidene-piperidin-1-yl)-heptylamine
175692-29-2

7-(4-Dibenzo[a,d]cyclohepten-5-ylidene-piperidin-1-yl)-heptylamine

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 83 percent / HOAc, conc. HCl / 2 h / 120 °C
2: Na2CO3 / 1,2-dichloro-ethane / 1) 0 deg C, 2) reflux
3: 1) CH3OH, 2) NaOH / 1) r.t., 15 min, 50 deg C, 15 min, 2) water
4: 99 percent / K2CO3 / acetonitrile / 90 °C
5: 81 percent / LiAlH4 / tetrahydrofuran; diethyl ether / 2 h / Ambient temperature
View Scheme
5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol
3967-32-6

5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol

7-(4-Dibenzo[a,d]cyclohepten-5-ylidene-piperidin-1-yl)-heptanenitrile
175692-23-6

7-(4-Dibenzo[a,d]cyclohepten-5-ylidene-piperidin-1-yl)-heptanenitrile

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 83 percent / HOAc, conc. HCl / 2 h / 120 °C
2: Na2CO3 / 1,2-dichloro-ethane / 1) 0 deg C, 2) reflux
3: 1) CH3OH, 2) NaOH / 1) r.t., 15 min, 50 deg C, 15 min, 2) water
4: 99 percent / K2CO3 / acetonitrile / 90 °C
View Scheme
5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol
3967-32-6

5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol

4-Dibenzo[a,d]cyclohepten-5-ylidene-piperidine-1-carboxylic acid 1-chloro-ethyl ester

4-Dibenzo[a,d]cyclohepten-5-ylidene-piperidine-1-carboxylic acid 1-chloro-ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 83 percent / HOAc, conc. HCl / 2 h / 120 °C
2: Na2CO3 / 1,2-dichloro-ethane / 1) 0 deg C, 2) reflux
View Scheme
5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol
3967-32-6

5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol

[4-(4-Dibenzo[a,d]cyclohepten-5-ylidene-piperidin-1-yl)-butyl]-((Z)-1-methylsulfanyl-2-nitro-vinyl)-amine

[4-(4-Dibenzo[a,d]cyclohepten-5-ylidene-piperidin-1-yl)-butyl]-((Z)-1-methylsulfanyl-2-nitro-vinyl)-amine

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 83 percent / HOAc, conc. HCl / 2 h / 120 °C
2: Na2CO3 / 1,2-dichloro-ethane / 1) 0 deg C, 2) reflux
3: 1) CH3OH, 2) NaOH / 1) r.t., 15 min, 50 deg C, 15 min, 2) water
4: 80 percent / Na2CO3, KI / acetonitrile; dimethylformamide / Heating
5: 62 percent / LiAlH4 / tetrahydrofuran; diethyl ether / 2 h / Ambient temperature
6: acetonitrile / Heating
View Scheme
5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol
3967-32-6

5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol

[7-(4-Dibenzo[a,d]cyclohepten-5-ylidene-piperidin-1-yl)-heptyl]-((Z)-1-methylsulfanyl-2-nitro-vinyl)-amine

[7-(4-Dibenzo[a,d]cyclohepten-5-ylidene-piperidin-1-yl)-heptyl]-((Z)-1-methylsulfanyl-2-nitro-vinyl)-amine

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 83 percent / HOAc, conc. HCl / 2 h / 120 °C
2: Na2CO3 / 1,2-dichloro-ethane / 1) 0 deg C, 2) reflux
3: 1) CH3OH, 2) NaOH / 1) r.t., 15 min, 50 deg C, 15 min, 2) water
4: 99 percent / K2CO3 / acetonitrile / 90 °C
5: 81 percent / LiAlH4 / tetrahydrofuran; diethyl ether / 2 h / Ambient temperature
6: acetonitrile / Heating
View Scheme
5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol
3967-32-6

5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol

1-[7-(4-Dibenzo[a,d]cyclohepten-5-ylidene-piperidin-1-yl)-heptyl]-3-[2-(2-guanidino-thiazol-4-ylmethylsulfanyl)-ethyl]-urea

1-[7-(4-Dibenzo[a,d]cyclohepten-5-ylidene-piperidin-1-yl)-heptyl]-3-[2-(2-guanidino-thiazol-4-ylmethylsulfanyl)-ethyl]-urea

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 83 percent / HOAc, conc. HCl / 2 h / 120 °C
2: Na2CO3 / 1,2-dichloro-ethane / 1) 0 deg C, 2) reflux
3: 1) CH3OH, 2) NaOH / 1) r.t., 15 min, 50 deg C, 15 min, 2) water
4: 99 percent / K2CO3 / acetonitrile / 90 °C
5: 81 percent / LiAlH4 / tetrahydrofuran; diethyl ether / 2 h / Ambient temperature
6: 1) THF, 0 deg C, 2) THF, DMF, r.t., 24 h
View Scheme
5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol
3967-32-6

5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol

N-[4-(2-{(Z)-1-[4-(4-Dibenzo[a,d]cyclohepten-5-ylidene-piperidin-1-yl)-butylamino]-2-nitro-vinylamino}-ethylsulfanylmethyl)-thiazol-2-yl]-guanidine

N-[4-(2-{(Z)-1-[4-(4-Dibenzo[a,d]cyclohepten-5-ylidene-piperidin-1-yl)-butylamino]-2-nitro-vinylamino}-ethylsulfanylmethyl)-thiazol-2-yl]-guanidine

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: 83 percent / HOAc, conc. HCl / 2 h / 120 °C
2: Na2CO3 / 1,2-dichloro-ethane / 1) 0 deg C, 2) reflux
3: 1) CH3OH, 2) NaOH / 1) r.t., 15 min, 50 deg C, 15 min, 2) water
4: 80 percent / Na2CO3, KI / acetonitrile; dimethylformamide / Heating
5: 62 percent / LiAlH4 / tetrahydrofuran; diethyl ether / 2 h / Ambient temperature
6: acetonitrile / Heating
7: NEt3 / methanol / 75 °C
View Scheme
5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol
3967-32-6

5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol

N-[4-(2-{(Z)-1-[7-(4-Dibenzo[a,d]cyclohepten-5-ylidene-piperidin-1-yl)-heptylamino]-2-nitro-vinylamino}-ethylsulfanylmethyl)-thiazol-2-yl]-guanidine

N-[4-(2-{(Z)-1-[7-(4-Dibenzo[a,d]cyclohepten-5-ylidene-piperidin-1-yl)-heptylamino]-2-nitro-vinylamino}-ethylsulfanylmethyl)-thiazol-2-yl]-guanidine

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: 83 percent / HOAc, conc. HCl / 2 h / 120 °C
2: Na2CO3 / 1,2-dichloro-ethane / 1) 0 deg C, 2) reflux
3: 1) CH3OH, 2) NaOH / 1) r.t., 15 min, 50 deg C, 15 min, 2) water
4: 99 percent / K2CO3 / acetonitrile / 90 °C
5: 81 percent / LiAlH4 / tetrahydrofuran; diethyl ether / 2 h / Ambient temperature
6: acetonitrile / Heating
7: NEt3 / methanol / 75 °C
View Scheme
5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol
3967-32-6

5-(1-methyl-4-piperidyl)-5H-dibenzocyclohepten-5-ol

cyproheptadine hydrochloride
969-33-5

cyproheptadine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In ethanol; water at 90℃; for 1h; Large scale;

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