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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

O-Methyl-L-threonine Manufacturer/High quality/Best price/In stock

Cas:4144-02-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 4144-02-9 with best price

Cas:4144-02-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO

O-Methyl-L-threonine manufacturer/supplier

Cas:4144-02-9

Min.Order:1 Gram

Negotiable

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

L-Threonine, O-methyl- 4144-02-9

Cas:4144-02-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Leader Biochemical Group

Overview of Our Factories Our Factories production lines Our Factories R&D ability Our Factories warehouse Our Factorie

China Biggest Factory & Manufacturer supply O-METHYL-L-THREONINE

Cas:4144-02-9

Min.Order:1 Gram

FOB Price: $30.0 / 35.0

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

O-METHYL-L-THREONINE CAS:4144-02-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic inter

O-METHYL-L-THREONINE CAS:4144-02-9

Cas:4144-02-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

L-Threonine, O-methyl-

Cas:4144-02-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

L-Threonine, O-methyl-

Cas:4144-02-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

O-methyl-l-threonine

Cas:4144-02-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

L-Threonine, O-methyl-

Cas:4144-02-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

O-methyl-l-threonine

Cas:4144-02-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

H-Thr(Me)-OH

Cas:4144-02-9

Min.Order:1 Milligram

Negotiable

Type:Trading Company

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SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

SAGECHEM/L-Thr(me)-OH

Cas:4144-02-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

O-methyl-l-threonine

Cas:4144-02-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

O-METHYL-L-THREONINE cas no. 4144-02-9 98%

Cas:4144-02-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Research Peptide Biotechnology Co., Ltd.

High purity, high success rate, short cycle and moderate priceAppearance:White powder solid Storage:Negative 20 degrees Celsius Package:5mg, 10mg 100mg, 1gram Application:Applied to various scientific research

L-Threonine, O-methyl-

Cas:4144-02-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

o-Methyl-L-threonine

Cas:4144-02-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

Ethyl 3,5-dihydroxybenzoate

Cas:4144-02-9

Min.Order:0

Negotiable

Type:Other

inquiry

SICHUAN TONGSHENG AMINOACID CO.LTD

Product Name:O-METHYL-L-THREONINE Application:APIs

O-METHYL-L-THREONINE

Cas:4144-02-9

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec O-Methyl-L-threonine 5g

Cas:4144-02-9

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

L-Threonine, O-methyl-

Cas:4144-02-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

O-METHYL-L-THREONINE

Cas:4144-02-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

GL Biochem (Shanghai) Ltd.

Application:Intermidates

H-Thr(Me)-OH

Cas:4144-02-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

L-Threonine, O-methyl-

Cas:4144-02-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Ocean Chemical Co., Ltd.

★.Best quality according to requirement ★.Competitive price in China market ★.Mature Technical support ★.Professional logistic support

O-Methyl-L-threonine

Cas:4144-02-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

DB BIOTECH CO., LTD

best seller Application:API

O-METHYL-L-THREONINE

Cas:4144-02-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

O-Methyl-L-threonine cas 4144-02-9Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

O-Methyl-L-threonine cas 4144-02-9

Cas:4144-02-9

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

O-METHYL-L-THREONINE

Cas:4144-02-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou ZeErRui Chemical Co., Ltd.

Hangzhou ZeErRui Chemical Co., Ltd. located in Lingang industrial areas, our plant covers an area of 6000 square meters.ZeErRui dedicated to the development, production and marketing of chemicals. We have earned ourselves a good reputation at home an

O-methyl-l-threonine manufacture

Cas:4144-02-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Food additive,Pharm

L-Thr(me)

Cas:4144-02-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

N-formyl-O-methyl-Ls-threonine
44975-87-3

N-formyl-O-methyl-Ls-threonine

O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

Conditions
ConditionsYield
With hydrogen bromide
(2S,3R)-2-Benzyloxycarbonylamino-3-methoxy-butyric acid; compound with dicyclohexyl-amine

(2S,3R)-2-Benzyloxycarbonylamino-3-methoxy-butyric acid; compound with dicyclohexyl-amine

O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

Conditions
ConditionsYield
(i) ion-exchange resin + form>, EtOH, H2O, (ii) H2, Pd-C; Multistep reaction;
Benzyloxycarbonyl-O-methyl-threonin
70561-63-6

Benzyloxycarbonyl-O-methyl-threonin

O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

Conditions
ConditionsYield
With hydrogen; Pd-BaSO4
methyl (2S,3R)-2-{[(benzyloxy)carbonyl]amino}-3-methoxybutanoate
4144-14-3

methyl (2S,3R)-2-{[(benzyloxy)carbonyl]amino}-3-methoxybutanoate

O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aq. LiOH / tetrahydrofuran
2: H2 / Pd/BaSO4
View Scheme
Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: acetic acid anhydride / 45 - 70 °C
2: brucine; ethanol
3: HBr
View Scheme
N-formyl-O-methyl-DL-threonine
6622-23-7, 7153-82-4, 7505-36-4, 44975-87-3

N-formyl-O-methyl-DL-threonine

O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: brucine; ethanol
2: HBr
View Scheme
N-Boc-L-Thr(Me)-OMe

N-Boc-L-Thr(Me)-OMe

O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

Conditions
ConditionsYield
With hydrogenchloride at 120℃; for 16h;
With hydrogenchloride In water at 110 - 120℃; for 16h;143 mg
perthamide C

perthamide C

A

sarcosine
107-97-1

sarcosine

B

O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

C

o-hydroxyl-phenylalanine
7423-92-9

o-hydroxyl-phenylalanine

D

cis-4-methyl-(S)-proline
6734-41-4

cis-4-methyl-(S)-proline

Conditions
ConditionsYield
With hydrogenchloride; water at 130℃;
perthamide C

perthamide C

A

O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

B

L-Aspartic acid
56-84-8

L-Aspartic acid

C

erythro-β-hydroxy-D-aspartic acid
5753-30-0

erythro-β-hydroxy-D-aspartic acid

Conditions
ConditionsYield
With hydrogenchloride; water at 160℃;
perthamide D

perthamide D

A

O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

B

L-Aspartic acid
56-84-8

L-Aspartic acid

C

L-phenylalanine
63-91-2

L-phenylalanine

D

erythro-β-hydroxy-D-aspartic acid
5753-30-0

erythro-β-hydroxy-D-aspartic acid

Conditions
ConditionsYield
With hydrogenchloride; water at 160℃;
(2S,3R)-2-((tert-butoxycarbonyl)amino)-3-methoxybutanoic acid
48068-25-3

(2S,3R)-2-((tert-butoxycarbonyl)amino)-3-methoxybutanoic acid

O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

Conditions
ConditionsYield
With trifluoroacetic acid In dichloromethane for 2h;572 mg
O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

methyl chloroformate
79-22-1

methyl chloroformate

(2S,3R)-3-methoxy-2-(methoxycarbonylamino)butanoic acid
1007881-21-1

(2S,3R)-3-methoxy-2-(methoxycarbonylamino)butanoic acid

Conditions
ConditionsYield
Stage #1: O-methyl-L-threonine; methyl chloroformate With sodium hydroxide In water at 0℃;
Stage #2: With hydrogenchloride In water pH=1;
97%
Stage #1: O-methyl-L-threonine; methyl chloroformate With sodium hydroxide In water at 0℃;
Stage #2: With hydrogenchloride In water pH=1;
97%
With sodium hydroxide In water at 0℃; for 12h;97%
O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide
82911-69-1

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-methyl-L-threonine

N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-methyl-L-threonine

Conditions
ConditionsYield
With sodium hydrogencarbonate In water; acetonitrile for 2h;95%
With sodium carbonate In 1,4-dioxane; water for 22h;60%
O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

(2S,3R)-2-((tert-butoxycarbonyl)amino)-3-methoxybutanoic acid
48068-25-3

(2S,3R)-2-((tert-butoxycarbonyl)amino)-3-methoxybutanoic acid

Conditions
ConditionsYield
With sodium hydrogencarbonate In tetrahydrofuran; water at 0 - 20℃; for 18h;94%
With sodium hydrogencarbonate
O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

L-threonine
72-19-5

L-threonine

Conditions
ConditionsYield
With sulfuric acid; sodium nitrite In water at 0 - 5℃;67%
With hydrogen bromide
O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

(2R,3R)-2-amino-3-methoxybutan-1-ol
1246891-52-0

(2R,3R)-2-amino-3-methoxybutan-1-ol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran Inert atmosphere; Reflux;55%
With diborane In tetrahydrofuran at 20 - 30℃; for 12h;
5-amino-2,4-dichloropyrimidine
5177-27-5

5-amino-2,4-dichloropyrimidine

O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

(7S)-2-chloro-7-((R)-1-methoxyethyl)-7,8-dihydropteridin-6(5H)-one

(7S)-2-chloro-7-((R)-1-methoxyethyl)-7,8-dihydropteridin-6(5H)-one

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In ethanol at 100℃; for 16h;54%
O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

Conditions
ConditionsYield
With sulfuric acid; potassium bromide; sodium nitrite
O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

ammonium thiocyanate
1147550-11-5

ammonium thiocyanate

acetic anhydride
108-24-7

acetic anhydride

(S)-3-acetyl-5-((R)-1-methoxy-ethyl)-2-thioxo-imidazolidin-4-one

(S)-3-acetyl-5-((R)-1-methoxy-ethyl)-2-thioxo-imidazolidin-4-one

Conditions
ConditionsYield
With acetic acid
O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

(E)-(S)-4-[((2S,3R)-2-tert-Butoxycarbonylamino-3-methoxy-butyryl)-methyl-amino]-2,5-dimethyl-hex-2-enoic acid ethyl ester

(E)-(S)-4-[((2S,3R)-2-tert-Butoxycarbonylamino-3-methoxy-butyryl)-methyl-amino]-2,5-dimethyl-hex-2-enoic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aq. NaHCO3
2: PyBOP; DIEA / CH2Cl2
View Scheme
O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

(E)-(S)-4-{[(2S,3R)-3-Methoxy-2-((S)-3-methyl-2-methylamino-3-phenyl-butyrylamino)-butyryl]-methyl-amino}-2,5-dimethyl-hex-2-enoic acid

(E)-(S)-4-{[(2S,3R)-3-Methoxy-2-((S)-3-methyl-2-methylamino-3-phenyl-butyrylamino)-butyryl]-methyl-amino}-2,5-dimethyl-hex-2-enoic acid

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: aq. NaHCO3
2: PyBOP; DIEA / CH2Cl2
3: HCl / dioxane
4: PyBOP; DIEA / CH2Cl2
5: aq. LiOH / methanol
6: Acid hydrolysis
View Scheme
O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

(E)-(S)-4-[((2S,3R)-2-Amino-3-methoxy-butyryl)-methyl-amino]-2,5-dimethyl-hex-2-enoic acid ethyl ester; hydrochloride

(E)-(S)-4-[((2S,3R)-2-Amino-3-methoxy-butyryl)-methyl-amino]-2,5-dimethyl-hex-2-enoic acid ethyl ester; hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: aq. NaHCO3
2: PyBOP; DIEA / CH2Cl2
3: HCl / dioxane
View Scheme
O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

(E)-(S)-4-({(2S,3R)-2-[(S)-2-(tert-Butoxycarbonyl-methyl-amino)-3-methyl-3-phenyl-butyrylamino]-3-methoxy-butyryl}-methyl-amino)-2,5-dimethyl-hex-2-enoic acid

(E)-(S)-4-({(2S,3R)-2-[(S)-2-(tert-Butoxycarbonyl-methyl-amino)-3-methyl-3-phenyl-butyrylamino]-3-methoxy-butyryl}-methyl-amino)-2,5-dimethyl-hex-2-enoic acid

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: aq. NaHCO3
2: PyBOP; DIEA / CH2Cl2
3: HCl / dioxane
4: PyBOP; DIEA / CH2Cl2
5: aq. LiOH / methanol
View Scheme
O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

(E)-(S)-4-({(2S,3R)-2-[(S)-2-(tert-Butoxycarbonyl-methyl-amino)-3-methyl-3-phenyl-butyrylamino]-3-methoxy-butyryl}-methyl-amino)-2,5-dimethyl-hex-2-enoic acid ethyl ester

(E)-(S)-4-({(2S,3R)-2-[(S)-2-(tert-Butoxycarbonyl-methyl-amino)-3-methyl-3-phenyl-butyrylamino]-3-methoxy-butyryl}-methyl-amino)-2,5-dimethyl-hex-2-enoic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: aq. NaHCO3
2: PyBOP; DIEA / CH2Cl2
3: HCl / dioxane
4: PyBOP; DIEA / CH2Cl2
View Scheme
O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

O3-methyl-4-deoxy-D-threonic acid
5405-44-7

O3-methyl-4-deoxy-D-threonic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aqueous sulfuric acid; sodium nitrite; potassium bromide
2: water; silver oxide
View Scheme
O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

(1-fluoro-2,4-dinitrophenyl)-5-L-alaninamide
139601-90-4

(1-fluoro-2,4-dinitrophenyl)-5-L-alaninamide

C14H18FN5O7

C14H18FN5O7

Conditions
ConditionsYield
With triethylamine In acetone; acetonitrile at 70℃;
O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

(2S,3R)-3-methoxy-2-(methoxycarbonylamino)butanoic acid
1007881-21-1

(2S,3R)-3-methoxy-2-(methoxycarbonylamino)butanoic acid

Conditions
ConditionsYield
0.28 g (20%)
O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

methyl ((1S,2R)-2-methoxy-1-(((2S)-2-(4-(2'-(2-((2S)-1-(N-(methoxycarbonyl)-O-methyl-L-threonyl-)-2-pyrrolidinyl)-1H-imidazol-4-yl)-5,5'-bi-thiazol-2-yl)-1H-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate trifluoroacetate

methyl ((1S,2R)-2-methoxy-1-(((2S)-2-(4-(2'-(2-((2S)-1-(N-(methoxycarbonyl)-O-methyl-L-threonyl-)-2-pyrrolidinyl)-1H-imidazol-4-yl)-5,5'-bi-thiazol-2-yl)-1H-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate trifluoroacetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sodium hydroxide / water / 0 °C
1.2: pH 1
2.1: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 3 h / 20 °C
View Scheme
O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

methyl ((1S,2R)-2-methoxy-1-(((2S)-2-(4-(5'-(2-((2S)-1-(N-(methoxycarbonyl)-O-methyl-L-threonyl-)-2-pyrrolidinyl)-1H-imidazol-4-yl)-2,2'-bi-1,3-thiazol-5-yl)-1H-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate trifluoroacetate

methyl ((1S,2R)-2-methoxy-1-(((2S)-2-(4-(5'-(2-((2S)-1-(N-(methoxycarbonyl)-O-methyl-L-threonyl-)-2-pyrrolidinyl)-1H-imidazol-4-yl)-2,2'-bi-1,3-thiazol-5-yl)-1H-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate trifluoroacetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sodium hydroxide / water / 0 °C
1.2: pH 1
2.1: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 16 h / 20 °C
View Scheme
O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

C12H16N4O5

C12H16N4O5

C17H25N5O8

C17H25N5O8

Conditions
ConditionsYield
With sodium hydrogencarbonate In acetone at 40℃; for 1h;
O-methyl-L-threonine
4144-02-9

O-methyl-L-threonine

dimethyl ((2S,2'S,3R,3'R)-((2S,2'S,3aS,3a'S,7aS,7a'S)-2,2'-(5,5'-(tricyclo[8.2.2.2(4,7)]hexadeca-4,6,10,12,13,15-hexaene-5,11-diyl)bis(1H-benzo[d]imidazole-5,2-diyl))bis(octahydro-1H-indole-2,1-diyl))bis(3-methoxy-1-oxobutane-2,1-diyl))dicarbamate
1415120-17-0

dimethyl ((2S,2'S,3R,3'R)-((2S,2'S,3aS,3a'S,7aS,7a'S)-2,2'-(5,5'-(tricyclo[8.2.2.2(4,7)]hexadeca-4,6,10,12,13,15-hexaene-5,11-diyl)bis(1H-benzo[d]imidazole-5,2-diyl))bis(octahydro-1H-indole-2,1-diyl))bis(3-methoxy-1-oxobutane-2,1-diyl))dicarbamate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sodium hydroxide / 1,4-dioxane / 16 h / 0 - 20 °C
1.2: pH 2
2.1: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 16 h / 0 - 20 °C
View Scheme

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