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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

(+)-aromadendrene

Cas:489-39-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hefei TNJ chemical industry co.,ltd

TNJ is a chemical company since 2001. Our specialization, your Confidence ! We keep committing to meet the needs of both market and customers with our innovative technology, high stable quality products and excellent service. We always combine econ

high quality AROMADENDRENE cas 489-39-4

Cas:489-39-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Content Natural Extract (+)-Aromadendrene HACCP manufacturer

Cas:489-39-4

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Product Name: (+)-AROMADENDRENE Synonyms: 1H-Cycloprop[e]azulene, decahydro-1,1,7-trimethyl-4-methylene-, (1aR,4aR,7R,7aR,7bS)-(+)-;aromandendrene;(+)-AROMADENDRENE;AROMADENDRENE, (+);(1R,2S,8R,11R)-7-METHYLENE-3,3,11-TRIMETHYL-TRICYCL

489-39-4 (+)-AROMADENDRENE

Cas:489-39-4

Min.Order:1 Gram

FOB Price: $8900.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 489-39-4 with fast shipping

Cas:489-39-4

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1H-Cycloprop[e]azulene,decahydro-1,1,7-trimethyl-4-methylene-, (1aR,4aR,7R,7aR,7bS)- 489-39-4

Cas:489-39-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:489-39-4

Cas:489-39-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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HANGZHOU YUNUO CHEMICAL CO.,LTD

superior quality Appearance:powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Used as Pharmaceutical Intermediates Transportation:as per your

1H-Cycloprop[e]azulene,decahydro-1,1,7-trimethyl-4-methylene-, (1aR,4aR,7R,7aR,7bS)-

Cas:489-39-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

(+)-AROMADENDRENE

Cas:489-39-4

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

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Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

10(14)-Aromadendrene

Cas:489-39-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

(+)-AroMadendrene

Cas:489-39-4

Min.Order:0

Negotiable

Type:Manufacturers

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals

(+)-AROMADENDRENE

Cas:489-39-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Wuxi TAA Chemical Industry Co.,LTD.

1.A strong technical force and advanced processing equipments. The quality of the products has been strictly inspected and all kinds of index have reached or exceeded domestic and international standards.2. Now we have established long-term stable re

high quality AROMADENDRENE cas 489-39-4

Cas:489-39-4

Min.Order:0

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Type:Other

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Antimex Chemical Limied

high quality AROMADENDRENE cas 489-39-4Appearance:Soily liquid Storage:It is recommended to store in a cool, dry and well ventilated areas and out of direct light. Store away from sources of heat or ignition. Keep containers well sealed when not in u

high quality AROMADENDRENE cas 489-39-4

Cas:489-39-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou Fandachem Co.,Ltd

1H-Cycloprop[e]azulene,decahydro-1,1,7-trimethyl-4-methylene-, (1aR,4aR,7R,7aR,7bS)-Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by expre

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

(+)-AROMADENDRENE

Cas:489-39-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Yuanye Bio-Technology Co., Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:100mg Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any po

(+)-Aromadendrene

Cas:489-39-4

Min.Order:0

Negotiable

Type:Trading Company

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Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

489-39-4

Cas:489-39-4

Min.Order:0

Negotiable

Type:Trading Company

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Zibo Hangyu Biotechnology Development Co., Ltd

home-produced Application:medicine

(+)-AROMADENDRENE

Cas:489-39-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

(+)-AROMADENDRENE

Cas:489-39-4

Min.Order:0

Negotiable

Type:Trading Company

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LEAP CHEM Co., Ltd.

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP

(+)-Aromadendrene

Cas:489-39-4

Min.Order:0

Negotiable

Type:Trading Company

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Changzhou Extraordinary Pharmatech co.,LTD

Changzhou Extraordinary Pharmatech co., LTD. As a leading chemical manufacturer and supplier in China.DAS authentication is passed.We can provide the popular precursor chemicals, we have our own strong R & D team, have our own laboratories and fa

(+)-Aromadendrene

Cas:489-39-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Jilin haofei import and export trade Co.,Ltd

Price, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right

high quality AROMADENDRENE cas 489-39-4 CAS NO.489-39-4

Cas:489-39-4

Min.Order:0

Negotiable

Type:Trading Company

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Dalian Yoking Chemical Co., Ltd.

OUR SERVICES Sourcing Service High quality, reliable supply, competitive pricing, regulatory compliance and fast delivery of your products are vital components of our sourcing strategy. We provide a one-stop sourcing service to global customers by s

Factory supply AROMADENDRENE

Cas:489-39-4

Min.Order:1 Kilogram

FOB Price: $1.0 / 5.0

Type:Trading Company

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shanghai longbang industry co.,ltd

Shanghai LONGBANG , Boasts strong competitive advantages by our well-trained chemists with rich professional backgroud. We aim to win the market via quick response and fast delivery, as well as continous development for high-tech medical compoun

(+)-Aromadendrene

Cas:489-39-4

Min.Order:10 Gram

Negotiable

Type:Trading Company

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Finetech Industry Limited

FINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the (+)-AROMADENDRENE, CAS:489-39-4 with the most competitive price and the best quality.

(+)-AROMADENDRENE

Cas:489-39-4

Min.Order:0

Negotiable

Type:Trading Company

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SHANGHAI ZZBIO CO., LTD.

High pure standard, Quick shippment COA with HPLC, MS and NMR spectra. Package:100mg Application:pharmaceutical industry, food industry, research

(+)-Aromadendrene

Cas:489-39-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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SINO GREAT ENTERPRISE LTD.

We are the lead producer and exporter in China.

Aromadendrene

Cas:489-39-4

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

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Sigma-Aldrich Chemie GmbH

(+)-Aromadendrene, a sesquiterpenoid, is the major constituent of the essential oil of Eucalypfus globulus. Package:1 mL in glass bottle Application:(+)-Aromadendrene may be used as a chiral starting material to synthesize other sesquiterenes such as

(+)-Aromadendrene

Cas:489-39-4

Min.Order:0

Negotiable

Type:Trading Company

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Synthetic route

Methanesulfonic acid (1aR,4S,4aR,7R,7aR,7bS)-1,1,7-trimethyl-decahydro-cyclopropa[e]azulen-4-ylmethyl ester
175985-51-0

Methanesulfonic acid (1aR,4S,4aR,7R,7aR,7bS)-1,1,7-trimethyl-decahydro-cyclopropa[e]azulen-4-ylmethyl ester

(+)-aromadendrene
489-39-4

(+)-aromadendrene

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In toluene at 100℃; for 18h;89%
(1aR,4aR,7R,7aS,7bS)-1,1,7-Trimethyldecahydro-4H-cyclopropa[e]azulen-4-one
99147-41-8

(1aR,4aR,7R,7aS,7bS)-1,1,7-Trimethyldecahydro-4H-cyclopropa[e]azulen-4-one

Methyltriphenylphosphonium bromide
1779-49-3

Methyltriphenylphosphonium bromide

(+)-aromadendrene
489-39-4

(+)-aromadendrene

Conditions
ConditionsYield
Stage #1: Methyltriphenylphosphonium bromide With n-butyllithium In tetrahydrofuran at -78 - 0℃; for 0.166667h; Inert atmosphere;
Stage #2: (1aR,4aR,7R,7aS,7bS)-1,1,7-Trimethyldecahydro-4H-cyclopropa[e]azulen-4-one In tetrahydrofuran at -78 - 20℃; for 24h; Inert atmosphere;
60%
(-)-globulol
489-41-8

(-)-globulol

(+)-aromadendrene
489-39-4

(+)-aromadendrene

Conditions
ConditionsYield
With pyridine; trichlorophosphate
(-)-O-<3,5-dinitro-benzoyl>-globulol

(-)-O-<3,5-dinitro-benzoyl>-globulol

(+)-aromadendrene
489-39-4

(+)-aromadendrene

Conditions
ConditionsYield
at 140℃; unter vermindertem Druck;
methyl (+)-(1S,7R)-8,8-dimethyl-3-oxobicyclo<5.1.0>octane-4-carboxylate
176199-11-4

methyl (+)-(1S,7R)-8,8-dimethyl-3-oxobicyclo<5.1.0>octane-4-carboxylate

(+)-aromadendrene
489-39-4

(+)-aromadendrene

Conditions
ConditionsYield
Multi-step reaction with 15 steps
1: 100 percent / LiAlH4 / diethyl ether / 1 h / Ambient temperature
2: imidazole / dimethylformamide / 12 h / Ambient temperature
3: 90 percent / Ley's tetrapropylammonium perruthenate, 4-methylmorpholine N-oxide, molecular sieves / CH2Cl2 / 0.25 h / Ambient temperature
4: 1.) LDA, HMPA / 1.) THF, -78 deg C, 30 min, 2.) THF, from -78 deg C to RT, 4 h
5: 96 percent / PdCl2, CuCl, air / dimethylformamide; H2O / 4.5 h / Ambient temperature
6: 84 percent / NaHMDS, HMPA / tetrahydrofuran / 0.67 h / -78 - -50 °C / a) -78 deg C. 15 min, b) 0 deg C, 15 min, c) 50 deg C, 10 min
7: 1.) lithium hexamethyldisilazane, HMPA / 1.) THF, -78 deg C, 1 h, 2.) THF, from -78 deg C to RT, 2 h
8: 86 percent / lithium tetramethyldisilazane, HMPA / tetrahydrofuran / 2 h / -78 - 20 °C
9: 93 percent / H2 / 5percent Pd/C / methanol / 2 h / 760 Torr / Ambient temperature
10: NaBH4 / methanol / 2 h / Ambient temperature
11: pyridine, DMAP / CH2Cl2 / 6 h / Ambient temperature
12: 68 percent / n-Bu3SnH, AIBN / toluene / 3 h / Heating
13: 100 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 6 h / Ambient temperature
14: 100 percent / Et3N, DMAP / CH2Cl2 / 2 h / 0 °C
15: 89 percent / DBU / toluene / 18 h / 100 °C
View Scheme
(1S,7R)-4-Hydroxymethyl-8,8-dimethyl-bicyclo[5.1.0]octan-3-ol

(1S,7R)-4-Hydroxymethyl-8,8-dimethyl-bicyclo[5.1.0]octan-3-ol

(+)-aromadendrene
489-39-4

(+)-aromadendrene

Conditions
ConditionsYield
Multi-step reaction with 14 steps
1: imidazole / dimethylformamide / 12 h / Ambient temperature
2: 90 percent / Ley's tetrapropylammonium perruthenate, 4-methylmorpholine N-oxide, molecular sieves / CH2Cl2 / 0.25 h / Ambient temperature
3: 1.) LDA, HMPA / 1.) THF, -78 deg C, 30 min, 2.) THF, from -78 deg C to RT, 4 h
4: 96 percent / PdCl2, CuCl, air / dimethylformamide; H2O / 4.5 h / Ambient temperature
5: 84 percent / NaHMDS, HMPA / tetrahydrofuran / 0.67 h / -78 - -50 °C / a) -78 deg C. 15 min, b) 0 deg C, 15 min, c) 50 deg C, 10 min
6: 1.) lithium hexamethyldisilazane, HMPA / 1.) THF, -78 deg C, 1 h, 2.) THF, from -78 deg C to RT, 2 h
7: 86 percent / lithium tetramethyldisilazane, HMPA / tetrahydrofuran / 2 h / -78 - 20 °C
8: 93 percent / H2 / 5percent Pd/C / methanol / 2 h / 760 Torr / Ambient temperature
9: NaBH4 / methanol / 2 h / Ambient temperature
10: pyridine, DMAP / CH2Cl2 / 6 h / Ambient temperature
11: 68 percent / n-Bu3SnH, AIBN / toluene / 3 h / Heating
12: 100 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 6 h / Ambient temperature
13: 100 percent / Et3N, DMAP / CH2Cl2 / 2 h / 0 °C
14: 89 percent / DBU / toluene / 18 h / 100 °C
View Scheme
(1aR,4S,4aR,7S,7aR,7bS)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-1,1,7-trimethyl-decahydro-cyclopropa[e]azulen-6-ol

(1aR,4S,4aR,7S,7aR,7bS)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-1,1,7-trimethyl-decahydro-cyclopropa[e]azulen-6-ol

(+)-aromadendrene
489-39-4

(+)-aromadendrene

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: pyridine, DMAP / CH2Cl2 / 6 h / Ambient temperature
2: 68 percent / n-Bu3SnH, AIBN / toluene / 3 h / Heating
3: 100 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 6 h / Ambient temperature
4: 100 percent / Et3N, DMAP / CH2Cl2 / 2 h / 0 °C
5: 89 percent / DBU / toluene / 18 h / 100 °C
View Scheme
(+)-(1S,2S,4R,7R)-4-tert-butyldimethylsiloxymethyl-8,8-dimethyl-2-(2-propenyl)bicyclo<5.1.0>octan-3-one
175985-40-7

(+)-(1S,2S,4R,7R)-4-tert-butyldimethylsiloxymethyl-8,8-dimethyl-2-(2-propenyl)bicyclo<5.1.0>octan-3-one

(+)-aromadendrene
489-39-4

(+)-aromadendrene

Conditions
ConditionsYield
Multi-step reaction with 11 steps
1: 96 percent / PdCl2, CuCl, air / dimethylformamide; H2O / 4.5 h / Ambient temperature
2: 84 percent / NaHMDS, HMPA / tetrahydrofuran / 0.67 h / -78 - -50 °C / a) -78 deg C. 15 min, b) 0 deg C, 15 min, c) 50 deg C, 10 min
3: 1.) lithium hexamethyldisilazane, HMPA / 1.) THF, -78 deg C, 1 h, 2.) THF, from -78 deg C to RT, 2 h
4: 86 percent / lithium tetramethyldisilazane, HMPA / tetrahydrofuran / 2 h / -78 - 20 °C
5: 93 percent / H2 / 5percent Pd/C / methanol / 2 h / 760 Torr / Ambient temperature
6: NaBH4 / methanol / 2 h / Ambient temperature
7: pyridine, DMAP / CH2Cl2 / 6 h / Ambient temperature
8: 68 percent / n-Bu3SnH, AIBN / toluene / 3 h / Heating
9: 100 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 6 h / Ambient temperature
10: 100 percent / Et3N, DMAP / CH2Cl2 / 2 h / 0 °C
11: 89 percent / DBU / toluene / 18 h / 100 °C
View Scheme
(+)-(1R,2S,4R,7S,8R,11S)-7-tert-butyldimethylsiloxymethyl-3,3,11-trimethyltricyclo<6.3.0.02,4>undecan-10-one
175985-45-2

(+)-(1R,2S,4R,7S,8R,11S)-7-tert-butyldimethylsiloxymethyl-3,3,11-trimethyltricyclo<6.3.0.02,4>undecan-10-one

(+)-aromadendrene
489-39-4

(+)-aromadendrene

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: NaBH4 / methanol / 2 h / Ambient temperature
2: pyridine, DMAP / CH2Cl2 / 6 h / Ambient temperature
3: 68 percent / n-Bu3SnH, AIBN / toluene / 3 h / Heating
4: 100 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 6 h / Ambient temperature
5: 100 percent / Et3N, DMAP / CH2Cl2 / 2 h / 0 °C
6: 89 percent / DBU / toluene / 18 h / 100 °C
View Scheme
(+)-(1R,2R,4R,7S)-7-tert-butyldimethylsiloxymethyl-3,3-dimethyltricyclo<6.3.0.02,4>undec-8-en-10-one
175985-44-1

(+)-(1R,2R,4R,7S)-7-tert-butyldimethylsiloxymethyl-3,3-dimethyltricyclo<6.3.0.02,4>undec-8-en-10-one

(+)-aromadendrene
489-39-4

(+)-aromadendrene

Conditions
ConditionsYield
Multi-step reaction with 9 steps
1: 1.) lithium hexamethyldisilazane, HMPA / 1.) THF, -78 deg C, 1 h, 2.) THF, from -78 deg C to RT, 2 h
2: 86 percent / lithium tetramethyldisilazane, HMPA / tetrahydrofuran / 2 h / -78 - 20 °C
3: 93 percent / H2 / 5percent Pd/C / methanol / 2 h / 760 Torr / Ambient temperature
4: NaBH4 / methanol / 2 h / Ambient temperature
5: pyridine, DMAP / CH2Cl2 / 6 h / Ambient temperature
6: 68 percent / n-Bu3SnH, AIBN / toluene / 3 h / Heating
7: 100 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 6 h / Ambient temperature
8: 100 percent / Et3N, DMAP / CH2Cl2 / 2 h / 0 °C
9: 89 percent / DBU / toluene / 18 h / 100 °C
View Scheme
(+)-(1S,2S,4R,7R)-4-tert-butyldimethylsiloxymethyl-8,8-dimethyl-2-(2-oxopropyl)bicyclo<5.1.0>octan-3-one
175985-43-0

(+)-(1S,2S,4R,7R)-4-tert-butyldimethylsiloxymethyl-8,8-dimethyl-2-(2-oxopropyl)bicyclo<5.1.0>octan-3-one

(+)-aromadendrene
489-39-4

(+)-aromadendrene

Conditions
ConditionsYield
Multi-step reaction with 10 steps
1: 84 percent / NaHMDS, HMPA / tetrahydrofuran / 0.67 h / -78 - -50 °C / a) -78 deg C. 15 min, b) 0 deg C, 15 min, c) 50 deg C, 10 min
2: 1.) lithium hexamethyldisilazane, HMPA / 1.) THF, -78 deg C, 1 h, 2.) THF, from -78 deg C to RT, 2 h
3: 86 percent / lithium tetramethyldisilazane, HMPA / tetrahydrofuran / 2 h / -78 - 20 °C
4: 93 percent / H2 / 5percent Pd/C / methanol / 2 h / 760 Torr / Ambient temperature
5: NaBH4 / methanol / 2 h / Ambient temperature
6: pyridine, DMAP / CH2Cl2 / 6 h / Ambient temperature
7: 68 percent / n-Bu3SnH, AIBN / toluene / 3 h / Heating
8: 100 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 6 h / Ambient temperature
9: 100 percent / Et3N, DMAP / CH2Cl2 / 2 h / 0 °C
10: 89 percent / DBU / toluene / 18 h / 100 °C
View Scheme
(1R,2S,4R,7S,8R,11S)-7-tert-butyldimethylsiloxymethyl-3,3,11-trimethyltricyclo<6.3.0.02,4>undec-10-yl phenyl thionocarbonate

(1R,2S,4R,7S,8R,11S)-7-tert-butyldimethylsiloxymethyl-3,3,11-trimethyltricyclo<6.3.0.02,4>undec-10-yl phenyl thionocarbonate

(+)-aromadendrene
489-39-4

(+)-aromadendrene

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 68 percent / n-Bu3SnH, AIBN / toluene / 3 h / Heating
2: 100 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 6 h / Ambient temperature
3: 100 percent / Et3N, DMAP / CH2Cl2 / 2 h / 0 °C
4: 89 percent / DBU / toluene / 18 h / 100 °C
View Scheme
((1aR,4S,4aR,7R,7aR,7bS)-1,1,7-trimethyldecahydro-1H-cyclopropa[e]azulen-4-yl)methanol
175985-50-9

((1aR,4S,4aR,7R,7aR,7bS)-1,1,7-trimethyldecahydro-1H-cyclopropa[e]azulen-4-yl)methanol

(+)-aromadendrene
489-39-4

(+)-aromadendrene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 100 percent / Et3N, DMAP / CH2Cl2 / 2 h / 0 °C
2: 89 percent / DBU / toluene / 18 h / 100 °C
View Scheme
(+)-(1S,4RS,7R)-8,8-dimethyl-4-hydroxymethylbicyclo[5.1.0]octan-3-one

(+)-(1S,4RS,7R)-8,8-dimethyl-4-hydroxymethylbicyclo[5.1.0]octan-3-one

(+)-aromadendrene
489-39-4

(+)-aromadendrene

Conditions
ConditionsYield
Multi-step reaction with 15 steps
1: LiAlH4 / diethyl ether / 0.25 h / 0 °C
2: imidazole / dimethylformamide / 12 h / Ambient temperature
3: 90 percent / Ley's tetrapropylammonium perruthenate, 4-methylmorpholine N-oxide, molecular sieves / CH2Cl2 / 0.25 h / Ambient temperature
4: 1.) LDA, HMPA / 1.) THF, -78 deg C, 30 min, 2.) THF, from -78 deg C to RT, 4 h
5: 96 percent / PdCl2, CuCl, air / dimethylformamide; H2O / 4.5 h / Ambient temperature
6: 84 percent / NaHMDS, HMPA / tetrahydrofuran / 0.67 h / -78 - -50 °C / a) -78 deg C. 15 min, b) 0 deg C, 15 min, c) 50 deg C, 10 min
7: 1.) lithium hexamethyldisilazane, HMPA / 1.) THF, -78 deg C, 1 h, 2.) THF, from -78 deg C to RT, 2 h
8: 86 percent / lithium tetramethyldisilazane, HMPA / tetrahydrofuran / 2 h / -78 - 20 °C
9: 93 percent / H2 / 5percent Pd/C / methanol / 2 h / 760 Torr / Ambient temperature
10: NaBH4 / methanol / 2 h / Ambient temperature
11: pyridine, DMAP / CH2Cl2 / 6 h / Ambient temperature
12: 68 percent / n-Bu3SnH, AIBN / toluene / 3 h / Heating
13: 100 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 6 h / Ambient temperature
14: 100 percent / Et3N, DMAP / CH2Cl2 / 2 h / 0 °C
15: 89 percent / DBU / toluene / 18 h / 100 °C
View Scheme
(1S,4R,7R)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-8,8-dimethyl-bicyclo[5.1.0]octan-3-ol

(1S,4R,7R)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-8,8-dimethyl-bicyclo[5.1.0]octan-3-ol

(+)-aromadendrene
489-39-4

(+)-aromadendrene

Conditions
ConditionsYield
Multi-step reaction with 13 steps
1: 90 percent / Ley's tetrapropylammonium perruthenate, 4-methylmorpholine N-oxide, molecular sieves / CH2Cl2 / 0.25 h / Ambient temperature
2: 1.) LDA, HMPA / 1.) THF, -78 deg C, 30 min, 2.) THF, from -78 deg C to RT, 4 h
3: 96 percent / PdCl2, CuCl, air / dimethylformamide; H2O / 4.5 h / Ambient temperature
4: 84 percent / NaHMDS, HMPA / tetrahydrofuran / 0.67 h / -78 - -50 °C / a) -78 deg C. 15 min, b) 0 deg C, 15 min, c) 50 deg C, 10 min
5: 1.) lithium hexamethyldisilazane, HMPA / 1.) THF, -78 deg C, 1 h, 2.) THF, from -78 deg C to RT, 2 h
6: 86 percent / lithium tetramethyldisilazane, HMPA / tetrahydrofuran / 2 h / -78 - 20 °C
7: 93 percent / H2 / 5percent Pd/C / methanol / 2 h / 760 Torr / Ambient temperature
8: NaBH4 / methanol / 2 h / Ambient temperature
9: pyridine, DMAP / CH2Cl2 / 6 h / Ambient temperature
10: 68 percent / n-Bu3SnH, AIBN / toluene / 3 h / Heating
11: 100 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 6 h / Ambient temperature
12: 100 percent / Et3N, DMAP / CH2Cl2 / 2 h / 0 °C
13: 89 percent / DBU / toluene / 18 h / 100 °C
View Scheme
tert-Butyl-dimethyl-((1aR,4S,4aR,7R,7aR,7bS)-1,1,7-trimethyl-decahydro-cyclopropa[e]azulen-4-ylmethoxy)-silane
175985-49-6

tert-Butyl-dimethyl-((1aR,4S,4aR,7R,7aR,7bS)-1,1,7-trimethyl-decahydro-cyclopropa[e]azulen-4-ylmethoxy)-silane

(+)-aromadendrene
489-39-4

(+)-aromadendrene

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 100 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 6 h / Ambient temperature
2: 100 percent / Et3N, DMAP / CH2Cl2 / 2 h / 0 °C
3: 89 percent / DBU / toluene / 18 h / 100 °C
View Scheme
(1S,4R,7R)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-8,8-dimethyl-bicyclo[5.1.0]octan-3-one
175985-39-4

(1S,4R,7R)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-8,8-dimethyl-bicyclo[5.1.0]octan-3-one

(+)-aromadendrene
489-39-4

(+)-aromadendrene

Conditions
ConditionsYield
Multi-step reaction with 12 steps
1: 1.) LDA, HMPA / 1.) THF, -78 deg C, 30 min, 2.) THF, from -78 deg C to RT, 4 h
2: 96 percent / PdCl2, CuCl, air / dimethylformamide; H2O / 4.5 h / Ambient temperature
3: 84 percent / NaHMDS, HMPA / tetrahydrofuran / 0.67 h / -78 - -50 °C / a) -78 deg C. 15 min, b) 0 deg C, 15 min, c) 50 deg C, 10 min
4: 1.) lithium hexamethyldisilazane, HMPA / 1.) THF, -78 deg C, 1 h, 2.) THF, from -78 deg C to RT, 2 h
5: 86 percent / lithium tetramethyldisilazane, HMPA / tetrahydrofuran / 2 h / -78 - 20 °C
6: 93 percent / H2 / 5percent Pd/C / methanol / 2 h / 760 Torr / Ambient temperature
7: NaBH4 / methanol / 2 h / Ambient temperature
8: pyridine, DMAP / CH2Cl2 / 6 h / Ambient temperature
9: 68 percent / n-Bu3SnH, AIBN / toluene / 3 h / Heating
10: 100 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 6 h / Ambient temperature
11: 100 percent / Et3N, DMAP / CH2Cl2 / 2 h / 0 °C
12: 89 percent / DBU / toluene / 18 h / 100 °C
View Scheme
(1aR,4S,7S,7aR,7bR)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-1,1,7-trimethyl-1a,3,4,7,7a,7b-hexahydro-1H,2H-cyclopropa[e]azulen-6-one
176199-13-6

(1aR,4S,7S,7aR,7bR)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-1,1,7-trimethyl-1a,3,4,7,7a,7b-hexahydro-1H,2H-cyclopropa[e]azulen-6-one

(+)-aromadendrene
489-39-4

(+)-aromadendrene

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: 93 percent / H2 / 5percent Pd/C / methanol / 2 h / 760 Torr / Ambient temperature
2: NaBH4 / methanol / 2 h / Ambient temperature
3: pyridine, DMAP / CH2Cl2 / 6 h / Ambient temperature
4: 68 percent / n-Bu3SnH, AIBN / toluene / 3 h / Heating
5: 100 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 6 h / Ambient temperature
6: 100 percent / Et3N, DMAP / CH2Cl2 / 2 h / 0 °C
7: 89 percent / DBU / toluene / 18 h / 100 °C
View Scheme
(1aR,4S,7R,7aR,7bR)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-1,1,7-trimethyl-1a,3,4,7,7a,7b-hexahydro-1H,2H-cyclopropa[e]azulen-6-one
175985-37-2

(1aR,4S,7R,7aR,7bR)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-1,1,7-trimethyl-1a,3,4,7,7a,7b-hexahydro-1H,2H-cyclopropa[e]azulen-6-one

(+)-aromadendrene
489-39-4

(+)-aromadendrene

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1: 86 percent / lithium tetramethyldisilazane, HMPA / tetrahydrofuran / 2 h / -78 - 20 °C
2: 93 percent / H2 / 5percent Pd/C / methanol / 2 h / 760 Torr / Ambient temperature
3: NaBH4 / methanol / 2 h / Ambient temperature
4: pyridine, DMAP / CH2Cl2 / 6 h / Ambient temperature
5: 68 percent / n-Bu3SnH, AIBN / toluene / 3 h / Heating
6: 100 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 6 h / Ambient temperature
7: 100 percent / Et3N, DMAP / CH2Cl2 / 2 h / 0 °C
8: 89 percent / DBU / toluene / 18 h / 100 °C
View Scheme
thiocyanic acid
463-56-9

thiocyanic acid

(+)-aromadendrene
489-39-4

(+)-aromadendrene

(-)-10(R)-Isothiocyanoaromadendrane
56012-90-9

(-)-10(R)-Isothiocyanoaromadendrane

Conditions
ConditionsYield
In chloroform for 48h; Ambient temperature;97%
for 48h; Ambient temperature;96.6%
In chloroform at 20℃; for 48h;74%
(+)-aromadendrene
489-39-4

(+)-aromadendrene

(1aR,4R,7R,7bS)-1,1,4,7-tetramethyl-1a,2,3,4,5,6,7,7b-octahydro-1H-cyclopropa[e]azulene
29484-27-3, 95910-36-4, 110769-61-4

(1aR,4R,7R,7bS)-1,1,4,7-tetramethyl-1a,2,3,4,5,6,7,7b-octahydro-1H-cyclopropa[e]azulene

Conditions
ConditionsYield
With aluminum oxide at 100℃;96%
With aluminum oxide; potassium In hexane at 0 - 20℃; for 12h;71%
(+)-aromadendrene
489-39-4

(+)-aromadendrene

[1aR-(1aα,7α,7aβ,7bα)]-1a,2,3,5,6,7,7a,7b-octahydro-1,1,4,7-tetramethyl-1H-cycloprop[e]azulene
74409-93-1, 77171-52-9, 128779-67-9, 21747-46-6

[1aR-(1aα,7α,7aβ,7bα)]-1a,2,3,5,6,7,7a,7b-octahydro-1,1,4,7-tetramethyl-1H-cycloprop[e]azulene

Conditions
ConditionsYield
With potassium tert-butylate In dimethyl sulfoxide at 100℃;80%
(+)-aromadendrene
489-39-4

(+)-aromadendrene

(1aR)-4ξ-hydroxymethyl-1,1,7c-trimethyl-(1ar,4ac,7at,7bc)-decahydro-cycloprop[e]azulen-4ξ-ol
95924-99-5, 97950-11-3, 145988-09-6

(1aR)-4ξ-hydroxymethyl-1,1,7c-trimethyl-(1ar,4ac,7at,7bc)-decahydro-cycloprop[e]azulen-4ξ-ol

Conditions
ConditionsYield
With osmium(VIII) oxide; 4-methylmorpholine N-oxide In water; tert-butyl alcohol at 20℃; for 64h;79%
With potassium permanganate In acetone
(i) OsO4, Et2O, (ii) aq. KOH, benzene, EtOH, mannitol; Multistep reaction;
(+)-aromadendrene
489-39-4

(+)-aromadendrene

phenylselenyl triflate
112238-64-9

phenylselenyl triflate

A

C21H30OSe
1114568-42-1

C21H30OSe

B

C21H30OSe
1114568-41-0

C21H30OSe

Conditions
ConditionsYield
With water In acetonitrile at 0 - 20℃; for 40h; optical yield given as %de;A 56%
B 40%
(+)-aromadendrene
489-39-4

(+)-aromadendrene

phenylselenyl triflate
112238-64-9

phenylselenyl triflate

A

(((1aR,4R,4aR,7R,7aS,7bS)-4-azido-1,1,7-trimethyldecahydro-1H-cyclopropa[e]azulen-4-yl)methyl)(phenyl)selane

(((1aR,4R,4aR,7R,7aS,7bS)-4-azido-1,1,7-trimethyldecahydro-1H-cyclopropa[e]azulen-4-yl)methyl)(phenyl)selane

B

(((1aR,4S,4aR,7R,7aS,7bS)-4-azido-1,1,7-trimethyldecahydro-1H-cyclopropa[e]azulen-4-yl)methyl)(phenyl)selane

(((1aR,4S,4aR,7R,7aS,7bS)-4-azido-1,1,7-trimethyldecahydro-1H-cyclopropa[e]azulen-4-yl)methyl)(phenyl)selane

Conditions
ConditionsYield
Stage #1: phenylselenyl triflate With sodium azide In chloroform at 0℃; for 0.5h;
Stage #2: (+)-aromadendrene In acetonitrile at 20℃; for 30h; Further stages.;
A 54%
B 16%
(+)-aromadendrene
489-39-4

(+)-aromadendrene

A

C15H24O3

C15H24O3

B

C15H24O3

C15H24O3

Conditions
ConditionsYield
Stage #1: (+)-aromadendrene With ferrous(II) sulfate heptahydrate; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; ozone In methanol; water at -78 - 20℃; for 0.0833333h;
Stage #2: With magnesium bis(monoperoxyphthalate)hexahydrate In methanol; water at 0℃; for 2h;
A 54%
B 37%
(+)-aromadendrene
489-39-4

(+)-aromadendrene

(1aR,4aR,7R,7aS,7bS)-1,1,7-Trimethyldecahydro-4H-cyclopropa[e]azulen-4-one
99147-41-8

(1aR,4aR,7R,7aS,7bS)-1,1,7-Trimethyldecahydro-4H-cyclopropa[e]azulen-4-one

Conditions
ConditionsYield
Stage #1: (+)-aromadendrene With sodium hydrogencarbonate; ozone In methanol; dichloromethane at -78℃; for 0.5h;
Stage #2: With triphenylphosphine In methanol; dichloromethane at 20℃; Inert atmosphere;
43%
With ozone
Multi-step reaction with 2 steps
1: O3 / pentane / -45 °C
2: 95 percent / Ph3P / CDCl3
View Scheme
Multi-step reaction with 2 steps
1: aq. KMnO4 / acetone
2: aq. NaIO4 / methanol
View Scheme
Multi-step reaction with 2 steps
1: 4-methylmorpholine N-oxide; osmium(VIII) oxide / tert-butyl alcohol; water / 64 h / 20 °C
2: sodium periodate / water; methanol / 2 h / 20 °C / Inert atmosphere
View Scheme
(+)-aromadendrene
489-39-4

(+)-aromadendrene

(1R,2S,6S,7S,10R)-3-Isopropyl-6,10-dimethyltricyclo[5.3.0.02,7]dec-3-ene

(1R,2S,6S,7S,10R)-3-Isopropyl-6,10-dimethyltricyclo[5.3.0.02,7]dec-3-ene

Conditions
ConditionsYield
With hexane; fluorosulfonylchloride; silver nitrate at -115 - -110℃;26%
isocyanate de chlorosulfonyle
1189-71-5

isocyanate de chlorosulfonyle

(+)-aromadendrene
489-39-4

(+)-aromadendrene

C16H25NO

C16H25NO

Conditions
ConditionsYield
Stage #1: isocyanate de chlorosulfonyle; (+)-aromadendrene In dichloromethane at 23℃; for 2h;
Stage #2: With triethylamine In dichloromethane at 23℃; for 3h;
Stage #3: With water In dichloromethane at 23℃; for 24h; diastereoselective reaction;
25%
(+)-aromadendrene
489-39-4

(+)-aromadendrene

A

(1S,2S,4R,7R,8R,11R)-3,3,11-trimethyl-7-hydroxymethyl-tricyclo<6.3.0.02,4>undecan-7-ol
145988-09-6

(1S,2S,4R,7R,8R,11R)-3,3,11-trimethyl-7-hydroxymethyl-tricyclo<6.3.0.02,4>undecan-7-ol

B

(1S,2S,3S,4R,7R,8R,11R)-3,7-bis(hydroxymethyl)-3,11-dimethyltricyclo<6.3.0.02,4>undecan-7-ol
145988-10-9

(1S,2S,3S,4R,7R,8R,11R)-3,7-bis(hydroxymethyl)-3,11-dimethyltricyclo<6.3.0.02,4>undecan-7-ol

Conditions
ConditionsYield
In N,N-dimethyl-formamide for 168h; Bacillus megaterium DSM 32;A 4 mg
B 7 mg
(+)-aromadendrene
489-39-4

(+)-aromadendrene

Nitrosochlorid von Aromadendren

Nitrosochlorid von Aromadendren

Conditions
ConditionsYield
With nitrosylchloride
methanol
67-56-1

methanol

(+)-aromadendrene
489-39-4

(+)-aromadendrene

A

(1R,2S,6S,7S,10R)-3-Isopropyl-3-methoxy-6,10-dimethyltricyclo[5.3.0.02,7]decane

(1R,2S,6S,7S,10R)-3-Isopropyl-3-methoxy-6,10-dimethyltricyclo[5.3.0.02,7]decane

B

(1R,2S,6S,7S,10R)-3-Isopropyl-6,10-dimethyltricyclo[5.3.0.02,7]dec-3-ene

(1R,2S,6S,7S,10R)-3-Isopropyl-6,10-dimethyltricyclo[5.3.0.02,7]dec-3-ene

Conditions
ConditionsYield
With fluorosulfonylchloride at -115 - -110℃;A 65 % Chromat.
B 18 % Chromat.
With fluorosulfonylchloride; fluorosulphonic acid 2.) (C2H5)2O; Yield given. Multistep reaction. Yields of byproduct given;
(+)-aromadendrene
489-39-4

(+)-aromadendrene

(1R,3S,7S,8S)-2,2,4,8-tetramethyltricyclo<5.3.1.03.7>undec-4-ene

(1R,3S,7S,8S)-2,2,4,8-tetramethyltricyclo<5.3.1.03.7>undec-4-ene

Conditions
ConditionsYield
With formic acid Heating; Yield given;
(+)-aromadendrene
489-39-4

(+)-aromadendrene

A

(1R,2S,6S,7S,10R)-3-Isopropyl-3-methoxy-6,10-dimethyltricyclo[5.3.0.02,7]decane

(1R,2S,6S,7S,10R)-3-Isopropyl-3-methoxy-6,10-dimethyltricyclo[5.3.0.02,7]decane

B

(1R,2S,6S,7S,10R)-3-Isopropyl-6,10-dimethyltricyclo[5.3.0.02,7]dec-3-ene

(1R,2S,6S,7S,10R)-3-Isopropyl-6,10-dimethyltricyclo[5.3.0.02,7]dec-3-ene

Conditions
ConditionsYield
With methanol; fluorosulfonylchloride; fluorosulphonic acid 2.) (C2H5)2O; Yield given. Multistep reaction. Yields of byproduct given;
(+)-aromadendrene
489-39-4

(+)-aromadendrene

(1R,3S,7S,8S)-2,2,4,8-tetramethyltricyclo[5.3.1.03,7]undec-4-ene

(1R,3S,7S,8S)-2,2,4,8-tetramethyltricyclo[5.3.1.03,7]undec-4-ene

Conditions
ConditionsYield
With formic acid Heating; Yield given;
(+)-aromadendrene
489-39-4

(+)-aromadendrene

(+)-aromadendrene ozonide

(+)-aromadendrene ozonide

Conditions
ConditionsYield
With ozone In pentane at -45℃;
(+)-aromadendrene
489-39-4

(+)-aromadendrene

(1S,2S,4R,7R,8R,11R)-3,3,11-trimethyl-7-hydroxymethyl-tricyclo<6.3.0.02,4>undecan-7-ol
145988-09-6

(1S,2S,4R,7R,8R,11R)-3,3,11-trimethyl-7-hydroxymethyl-tricyclo<6.3.0.02,4>undecan-7-ol

Conditions
ConditionsYield
With osmium(VIII) oxide; potassium carbonate; potassium hexacyanoferrate(III) In water; tert-butyl alcohol for 24h; Ambient temperature;900 mg
(+)-aromadendrene
489-39-4

(+)-aromadendrene

7-isopropyl-1,4-dimethyl-azulene
489-84-9

7-isopropyl-1,4-dimethyl-azulene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: 96 percent / K/Al2O3 / 100 °C
2.1: BF3*Et2O / CH2Cl2 / 3 h / 20 °C
2.2: 42 mg / sulfur / 1,3,5-trimethyl-benzene / 160 °C
View Scheme
(+)-aromadendrene
489-39-4

(+)-aromadendrene

(1aR,4S,7R,7aS,7bR)-1,1,4,7-tetramethyl-1a,2,3,4,6,7,7a,7b-octahydro-1H-cyclopropa[e]azulen-4-ol
63181-42-0

(1aR,4S,7R,7aS,7bR)-1,1,4,7-tetramethyl-1a,2,3,4,6,7,7a,7b-octahydro-1H-cyclopropa[e]azulen-4-ol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 80 percent / KOtBu / dimethylsulfoxide / 100 °C
2: 96 percent / oxone; NaHCO3; 18-crown-6 / CH2Cl2; H2O; acetone / 2 h / 0 °C
3: 57 percent / diethylamine; n-butyllithium / diethyl ether; hexane / 0 - 20 °C
View Scheme
(+)-aromadendrene
489-39-4

(+)-aromadendrene

(1aR,4S,4aR,7R,7aS,7bR)-1,1,4,7-tetramethyldecahydro-4aH-cyclopropa[e]azulene-4,4a-diol
6894-71-9

(1aR,4S,4aR,7R,7aS,7bR)-1,1,4,7-tetramethyldecahydro-4aH-cyclopropa[e]azulene-4,4a-diol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 80 percent / KOtBu / dimethylsulfoxide / 100 °C
2: 54 percent / KMnO4 / ethanol; H2O / 2 h / 0 °C
View Scheme
(+)-aromadendrene
489-39-4

(+)-aromadendrene

(2aR,8R,8aR,8bR)-2,2,5,8-tetramethyl-2a,3,4,6,7,8,8a,8b-octahydro-2H-naphtho[1,8-bc]furan

(2aR,8R,8aR,8bR)-2,2,5,8-tetramethyl-2a,3,4,6,7,8,8a,8b-octahydro-2H-naphtho[1,8-bc]furan

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 80 percent / KOtBu / dimethylsulfoxide / 100 °C
2: 54 percent / KMnO4 / ethanol; H2O / 2 h / 0 °C
3: acetic acid; iodine / tetrahydrofuran; H2O / 96 h / 20 °C
View Scheme
Multi-step reaction with 3 steps
1: 80 percent / KOtBu / dimethylsulfoxide / 100 °C
2: 96 percent / oxone; NaHCO3; 18-crown-6 / CH2Cl2; H2O; acetone / 2 h / 0 °C
3: 45 percent / sulfuric acid / tetrahydrofuran; H2O / 2 h / 30 °C
View Scheme
(+)-aromadendrene
489-39-4

(+)-aromadendrene

(1R,3aR,4aS,6aR,7aR,7bS)-1,4a,7,7-tetramethyldecahydrocyclopropa[7,8]azuleno[3a,4-b]oxirene
178602-94-3

(1R,3aR,4aS,6aR,7aR,7bS)-1,4a,7,7-tetramethyldecahydrocyclopropa[7,8]azuleno[3a,4-b]oxirene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 80 percent / KOtBu / dimethylsulfoxide / 100 °C
2: 96 percent / oxone; NaHCO3; 18-crown-6 / CH2Cl2; H2O; acetone / 2 h / 0 °C
View Scheme

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