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AstaTech ( Chengdu) BioPharmaceutical Corp.

Chengdu AstaTech Chemical Technology Co., Ltd. is a wholly-owned subsidiary of AstaTech (Chengdu) BioPharmaceutical Co., Ltd. It has overall accountability for AstaTech’s product list and sales and promotion of chemical reagents in China. The company

(3R)-3-Amino-1-butanol

Cas:61477-40-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality (R)-3-amino-1-butanol supplier in China

Cas:61477-40-5

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Sinoway Industrial Co., Ltd.

Assay: 99% up; Stable supply with over 10Mt annually; Appearance:transparent liquid Storage:room temprature Package:1kg/bottle, 25kg/drum Application:Intermediate of Dolutegravir Port:Beijing/Shanghai/Shenzhen/Hangzhou

(R)-3-amino-1-butanol, Intermediate of Dolutegravir

Cas:61477-40-5

Min.Order:1 Kilogram

FOB Price: $100.0 / 110.0

Type:Trading Company

inquiry

Jinan Finer Chemical Co., Ltd

Product description: Product name (3R)-3-Amino-1-butanol CAS number 61477-40-5 Assay ≥98% Appearance Colorless liquid Capacity 200mt/year Application Pharmaceutical intermedi

(3R)-3-Amino-1-butanol

Cas:61477-40-5

Min.Order:10 Gram

FOB Price: $12.0

Type:Lab/Research institutions

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Unique advantages Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:Transparent liquid Storage:cool dry place Package:25kg/drum Application:pharmaceutical intermediate Transportation

Manufacturer high quality (3R)-3-Amino-1-butanol Cas 61477-40-5 with good price

Cas:61477-40-5

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

(R)-3-AMINO-1-BUTANOL

Cas:61477-40-5

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply (3R)-3-aminobutan-1-ol

Cas:61477-40-5

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% 61477-40-5 (R)-3-amino-1-butanol Manufacturer

Cas:61477-40-5

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

(R)-3-AMINO-1-BUTANOL

Cas:61477-40-5

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Shanghai SE Pharm Co., Ltd

1. made in GMP plant, commerially 2. Normal Stock: 500kgs 3. Audit accepted. Related documents are available to offer and audited by many clients, such as Lupin, MSN, Dr reddy etc 4. Chromatographic Purity (HPLC): not less than 99

(3R)-3-Amino-1-butanol

Cas:61477-40-5

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine c

(R)-3-Aminobutan-1-ol

Cas:61477-40-5

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

(R)-3-Aminobutan-1-ol -- CHemwill

Cas:61477-40-5

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Tianfu Chemical, built in 2009, is a professional supplier for API materials in China. With 10 years development, we have bulit our own factory and lab to produce a certain of products. And we have established stable business relationship

TIANFU CHEM 61477-40-5 (R)-3-AMINO-1-BUTANOL

Cas:61477-40-5

Min.Order:1 Kilogram

FOB Price: $200.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

CAS 61477-40-5 (3R) -3-Amino-1-Butanol

Cas:61477-40-5

Min.Order:1 Gram

FOB Price: $6.0 / 9.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product Name:(R)-3-Aminobutan-1-ol Cas:61477-40-5 MF:C4H11NO MW:89.14 Appearance:White Powder Storage:Store in cool and dry place, away from sun light. Package:25kg Application:APIs Transportation:By sea or by air Port:Qingdao Port

(R)-3-Aminobutan-1-ol

Cas:61477-40-5

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 61477-40-5 with best quality

Cas:61477-40-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

(3R)-3-Amino-1-butanol

Cas:61477-40-5

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry pla

(3R)-3-Amino-1-butanol Cas 61477-40-5 Dolutegravir Intermediate

Cas:61477-40-5

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Hangzhou Think Chemical Co. Ltd

(3R)-3-Amino-1-butanol CAS No.:61477-40-5 HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketing & distribut

High purity (3R)-3-Amino-1-butanol CAS No.:61477-40-5

Cas:61477-40-5

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1-Butanol, 3-amino-, (3R)- 61477-40-5

Cas:61477-40-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

(R)-3-AMINO-1-BUTANOL CAS:61477-40-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic int

(R)-3-AMINO-1-BUTANOL CAS:61477-40-5

Cas:61477-40-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1-Butanol, 3-amino-, (3R)-

Cas:61477-40-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:61477-40-5

Cas:61477-40-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Mojin Biotechnology Co.,Ltd

Hebei Mojin Biotechnology Co., Ltd, Our company is a professional chemical raw materials and chemical reagents research and development production enterprises. We have several production line,So we can control the lowest price. We also have several

(3R)-3-Amino-1-butanol cas:61477-40-5

Cas:61477-40-5

Min.Order:25 Gram

FOB Price: $90.0 / 100.0

Type:Trading Company

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

cas 61477-40-5 CAS 61477-40-5 (R)-3-AMINO-1-BUTANOL

Cas:61477-40-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

Basic Information Product Name: (R)-3-AMINOBUTAN-1-OL CAS: 61477-40-5 English Synonyms: (3R)-3-AMINOBUTAN-1-OL ; 1-BUTANOL,3-AMINO-, (3R)- ; (-)-(R)-3-AMINOPROP

(R)-3-AMINO-1-BUTANOL

Cas:61477-40-5

Min.Order:1 Milligram

FOB Price: $0.5 / 1.0

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Service 1.Own made fine chemical products 2.Out sourcing and qua

(R)-3-Aminobutan-1-ol

Cas:61477-40-5

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

high purity (R)-3-AMINO-1-BUTANOL

Cas:61477-40-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

HANWAYS CHEMPHARM CO.,LIMITED

We are concentrating on the R&D and technical service of APIs and pharmaceutical intermediates Application:Pharmaceutical intermediate Port:Chinese main port

(3R)-3-Amino-1-butanol

Cas:61477-40-5

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shanghai Hope Chem Co., Ltd

1. Product advantages: exquisite appearance and unique functions. 2. Product Advantages: Our products are the best,fast speed ,in large stock 3. High-quality products and thoughtful service are your greatest satisfaction. 4. The product

(3R)-3-Amino-1-butanol

Cas:61477-40-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

(R)-3-acetamidobutanol

(R)-3-acetamidobutanol

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

Conditions
ConditionsYield
In ethanol at 70 - 80℃; Alkaline conditions;97.5%
(-)-(3R)-3-((benzyloxycarbonyl)amino)butanol
866395-21-3

(-)-(3R)-3-((benzyloxycarbonyl)amino)butanol

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

Conditions
ConditionsYield
With palladium 10% on activated carbon; hydrogen In ethanol at 50 - 60℃; under 3000.3 - 4500.45 Torr;96%
(-)-tert-butyl [(R)-3-hydroxy-1-methylpropyl]carbamate
167216-17-3

(-)-tert-butyl [(R)-3-hydroxy-1-methylpropyl]carbamate

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

Conditions
ConditionsYield
With trifluoroacetic acid In dichloromethane at 0 - 10℃;95.8%
With hydrogenchloride In methanol; water at 25℃; for 6h; Green chemistry;90%
With hydrogenchloride In methanol at 25℃;0.5 g
(3R)-3-{[(1R)-1-phenylethyl]amino}butan-1-ol

(3R)-3-{[(1R)-1-phenylethyl]amino}butan-1-ol

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

Conditions
ConditionsYield
With platinum on carbon In ethanol at 60℃; under 15001.5 Torr; for 10h; Reagent/catalyst;95.4%
(R)-3-amino-1-butanol L-malate

(R)-3-amino-1-butanol L-malate

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

Conditions
ConditionsYield
With sodium methylate In methanol at 20℃; Solvent; Reagent/catalyst;95.3%
With sodium hydroxide In isopropyl alcohol at 10 - 20℃; for 0.666667h;12.9 g
(R)-3-amino-1-butanol tartarate

(R)-3-amino-1-butanol tartarate

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 40 - 45℃; Reagent/catalyst; Temperature;95%
(R)-3-benzamido-1-butanol

(R)-3-benzamido-1-butanol

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

Conditions
ConditionsYield
In ethanol at 70 - 80℃; Alkaline conditions;92.6%
With hydrogenchloride In water for 3h; Reflux;90%
(R)-4-hydroxybutan-2-aminium (S)-2-hydroxy-2-phenylacetate
1236049-43-6

(R)-4-hydroxybutan-2-aminium (S)-2-hydroxy-2-phenylacetate

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

Conditions
ConditionsYield
With triethanolamine; sodium methylate In methanol at 80 - 100℃; under 3.75038 - 562.556 Torr;91%
With sodium methylate In methanol at 20℃; for 2h;35 g
With sodium methylate In methanol at 65℃; for 17h;
(R)-3-aminobutanol tartrate

(R)-3-aminobutanol tartrate

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

Conditions
ConditionsYield
With potassium carbonate In methanol at 45 - 50℃; for 12h;90%
(R)-3-aminobutanoic acid
3775-73-3

(R)-3-aminobutanoic acid

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

Conditions
ConditionsYield
With sodium tetrahydroborate; trifluoroacetic acid In tetrahydrofuran at 20℃; Reagent/catalyst; Temperature; Solvent; Inert atmosphere; Cooling with ice;84.3%
With sodium tetrahydroborate; zinc(II) chloride In tetrahydrofuran at 20 - 60℃; for 3.5h; Autoclave;54%
(R)-3-benzamido-1-butanol

(R)-3-benzamido-1-butanol

A

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

B

benzoic acid
65-85-0

benzoic acid

Conditions
ConditionsYield
With hydrogenchloride for 5h; Heating;A 83%
B 37.2 g
1-(tert-butyldimethylsilyloxy)-3-aminobutane
245728-81-8

1-(tert-butyldimethylsilyloxy)-3-aminobutane

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran for 1h;80%
(R)-3-amino-butyric acid ethyl ester hydrochloride

(R)-3-amino-butyric acid ethyl ester hydrochloride

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

Conditions
ConditionsYield
Stage #1: (R)-3-amino-butyric acid ethyl ester hydrochloride With sodium hydrogencarbonate In water at 20℃; for 0.25h; Cooling with ice;
Stage #2: With potassium borohydride In ethanol at 20℃; for 12h;
77%
(R)-3-aminobutanoic acid methyl ester hydrochloride
139243-54-2

(R)-3-aminobutanoic acid methyl ester hydrochloride

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

Conditions
ConditionsYield
Stage #1: (R)-3-aminobutanoic acid methyl ester hydrochloride With sodium hydrogencarbonate In water for 0.25h; Cooling with ice;
Stage #2: With potassium borohydride In methanol at 20℃; for 12h;
76%
(R)-methyl 3-aminobutanoate hydrochloride
6078-06-4, 83509-89-1, 102522-53-2, 103189-63-5

(R)-methyl 3-aminobutanoate hydrochloride

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

Conditions
ConditionsYield
With RuH(η1-BH4)(dppp)((R,R)-dpen); hydrogen In tetrahydrofuran at 80℃; under 37503.8 Torr; for 16h; Autoclave;62%
With hydrogen; C40H39BN2P2Ru In tetrahydrofuran at 80℃; under 26252.6 - 37503.8 Torr; for 14h; Product distribution / selectivity;n/a
(3R)-3-methyl-3-[((1S)-1-phenylethyl)amino]propan-1-ol
60920-20-9

(3R)-3-methyl-3-[((1S)-1-phenylethyl)amino]propan-1-ol

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In ethanol
3-aminobutanoic acid ethyl ester
5303-65-1

3-aminobutanoic acid ethyl ester

A

(+)-(S)-3-aminopropan-1-ol
61477-39-2

(+)-(S)-3-aminopropan-1-ol

B

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

Conditions
ConditionsYield
With lithium aluminium tetrahydride Yield given. Yields of byproduct given. Title compound not separated from byproducts;
methyl 3-((methoxycarbonyl)amino)-3-methylpropanoate
116173-78-5, 116173-72-9

methyl 3-((methoxycarbonyl)amino)-3-methylpropanoate

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

Conditions
ConditionsYield
With lithium aluminium tetrahydride; hydrogen bromide 1.) AcOH; 2.) THF; Multistep reaction;
2-hydroxymethyl-N-(3-hydroxy-1-methyl-propyl)-benzamide
866395-51-9

2-hydroxymethyl-N-(3-hydroxy-1-methyl-propyl)-benzamide

A

2-benzofuran-1(3H)-one
87-41-2

2-benzofuran-1(3H)-one

B

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

Conditions
ConditionsYield
With acetic acid at 80℃;
(3R)-3-{benzyl[(1R)-1-phenylethyl]amino}butanol
899806-42-9

(3R)-3-{benzyl[(1R)-1-phenylethyl]amino}butanol

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

Conditions
ConditionsYield
With hydrogen; palladium hydroxide on carbon In methanol under 1551.49 Torr; for 24h;
tert-butyl (R)-3-amino-3-methyl-propionate
120686-16-0

tert-butyl (R)-3-amino-3-methyl-propionate

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

Conditions
ConditionsYield
With potassium hydroxide; aluminium trichloride In diethyl ether; water
C8H13NO3

C8H13NO3

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

Conditions
ConditionsYield
With potassium hydroxide In ethanol; water at 20 - 85℃; for 2h;
1-Hydroxy-3-butanone
590-90-9

1-Hydroxy-3-butanone

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

Conditions
ConditionsYield
With SEC-BUTYLAMINE; magnesium chloride In aq. phosphate buffer; dimethyl sulfoxide at 15℃; for 24h; Reagent/catalyst; Solvent; Temperature; Enzymatic reaction;0.45 g
With glucose dehydrogenase; ammonium hydroxide; D-glucose; NAD; ammonium chloride; lysozyme; DNase I In water at 30℃; for 24h; Reagent/catalyst; Enzymatic reaction; enantioselective reaction;n/a
(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

methyl 1-(2,2-dihydroxyethyl)-4-oxo-3-[(phenylmethyl)oxy]-1,4-dihydro-2-pyridinecarboxylate
1206102-08-0

methyl 1-(2,2-dihydroxyethyl)-4-oxo-3-[(phenylmethyl)oxy]-1,4-dihydro-2-pyridinecarboxylate

(4R,12aS)-7-(benzyloxy)-4-methyl-3,4,12,12a-tetrahydro-2H-pyrido[1′,2’:4,5] pyrazino[2,1-b][1,3]oxazine-6,8-dione
1206102-09-1

(4R,12aS)-7-(benzyloxy)-4-methyl-3,4,12,12a-tetrahydro-2H-pyrido[1′,2’:4,5] pyrazino[2,1-b][1,3]oxazine-6,8-dione

Conditions
ConditionsYield
With acetic acid In toluene at 90℃; for 3.5h;96%
With acetic acid In toluene at 90℃; for 2.5h; Product distribution / selectivity;83%
With acetic acid In methanol; toluene at 90℃; for 2.5h; Reagent/catalyst; Temperature;83%
With acetic acid In toluene at 90℃; for 2h; diastereoselective reaction;80%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

(-)-tert-butyl [(R)-3-hydroxy-1-methylpropyl]carbamate
167216-17-3

(-)-tert-butyl [(R)-3-hydroxy-1-methylpropyl]carbamate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 25℃; for 16h;91.3%
With triethylamine In dichloromethane at 20 - 24℃; for 4h;80%
With triethylamine In dichloromethane at 20℃; for 4h;
With triethylamine In dichloromethane at 0 - 20℃; for 1h;
(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

benzaldehyde
100-52-7

benzaldehyde

(R)-3-(benzylamino)butan-1-ol

(R)-3-(benzylamino)butan-1-ol

Conditions
ConditionsYield
Stage #1: (R)-3-amino-1-butanol; benzaldehyde In methanol at 20℃; for 1h;
Stage #2: With methanol; sodium tetrahydroborate at 0 - 20℃; for 2.33333h;
90%
(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

methyl 5-(2,4-difluorobenzylcarbamoyl)-3-methoxy-4-oxo-1-(2-oxoethyl)-1,4-dihydropyridine-2-carboxylate

methyl 5-(2,4-difluorobenzylcarbamoyl)-3-methoxy-4-oxo-1-(2-oxoethyl)-1,4-dihydropyridine-2-carboxylate

A

(4R,12aS)-N-(2,4-difluorobenzyl)-7-methyloxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido [1',2',:4,5]pyrazino[2,1-b] [1,3]oxazine-9-carboxamide
1335210-35-9

(4R,12aS)-N-(2,4-difluorobenzyl)-7-methyloxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido [1',2',:4,5]pyrazino[2,1-b] [1,3]oxazine-9-carboxamide

B

N-(2,4-difluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide

N-(2,4-difluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide

C

(R)-N-(2,4-difluorobenzyl)-2-(4-hydroxybutan-2-yl)-9-methoxy-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxamide

(R)-N-(2,4-difluorobenzyl)-2-(4-hydroxybutan-2-yl)-9-methoxy-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxamide

Conditions
ConditionsYield
In toluene; acetonitrile at 100℃; under 5171.62 Torr; Flow reactor;A n/a
B n/a
C 88%
(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

C18H17NO7
1246617-67-3

C18H17NO7

C21H22N2O6
1357289-10-1

C21H22N2O6

Conditions
ConditionsYield
With acetic acid In methanol; toluene at 90℃; for 3h;81%
methyl 3-(benzyloxy)-5-(2,4-difluorobenzylcarbamoyl)-4-oxo-1-(2-oxoethyl)-1,4-dihydropyridine-2-carboxylate
1229006-25-0

methyl 3-(benzyloxy)-5-(2,4-difluorobenzylcarbamoyl)-4-oxo-1-(2-oxoethyl)-1,4-dihydropyridine-2-carboxylate

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

(4R,12aS)-7-(benzyloxy)-N-(2,4-difluorobenzyl)-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1′,2’:4,5]-pyrazino[2,1-b][1,3]oxazine-9-carboxamide
1206102-11-5

(4R,12aS)-7-(benzyloxy)-N-(2,4-difluorobenzyl)-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1′,2’:4,5]-pyrazino[2,1-b][1,3]oxazine-9-carboxamide

Conditions
ConditionsYield
With acetic acid In dichloromethane at 140℃; Microwave irradiation;81%
With acetic acid In methanol; toluene at 90℃; for 2h;65%
With acetic acid In methanol; toluene at 120℃; for 4h;0.2 g
(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

C22H26F2N2O7

C22H26F2N2O7

C22H23F2N3O5

C22H23F2N3O5

Conditions
ConditionsYield
Stage #1: C22H26F2N2O7 With methanesulfonic acid; acetic acid In acetonitrile at 25 - 70℃; for 9h;
Stage #2: (R)-3-amino-1-butanol In acetonitrile at 65 - 70℃; for 5h;
81%
4-tolyl iodide
624-31-7

4-tolyl iodide

(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

(R)-N-(4-hydroxybutan-2-yl)-p-toluidine

(R)-N-(4-hydroxybutan-2-yl)-p-toluidine

Conditions
ConditionsYield
With copper(l) iodide; potassium carbonate; L-proline In dimethyl sulfoxide at 120℃; for 12h; Inert atmosphere;79%
(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

C20H21NO7
1246616-87-4

C20H21NO7

(4R,12aS)-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-7-(phenylmethoxy)-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic acid ethyl ester
1357289-04-3

(4R,12aS)-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-7-(phenylmethoxy)-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic acid ethyl ester

Conditions
ConditionsYield
With acetic acid In methanol; toluene for 3h; Reflux;78%
(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

C20H17N5O3S

C20H17N5O3S

C24H26N6O3S

C24H26N6O3S

Conditions
ConditionsYield
Stage #1: (R)-3-amino-1-butanol; C20H17N5O3S In tetrahydrofuran for 0.166667h; Inert atmosphere;
Stage #2: With N-ethyl-N,N-diisopropylamine; HATU In tetrahydrofuran for 2h; Reflux;
76%
(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

C19H20F2N2O7

C19H20F2N2O7

C23H29F2N3O7

C23H29F2N3O7

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 2h;76%
(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

tetraethyl 7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3,5,6-tetracarboxylate

tetraethyl 7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3,5,6-tetracarboxylate

C26H42N2O10

C26H42N2O10

Conditions
ConditionsYield
In neat (no solvent) at 20℃; Schlenk technique;74%
(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

C4H9N3O

C4H9N3O

Conditions
ConditionsYield
Stage #1: (R)-3-amino-1-butanol With copper(II) sulfate; triethylamine In water; acetonitrile at 0℃; for 0.0833333h; Inert atmosphere;
Stage #2: With imidazole-1-sulfonyl azide hydrochloride In water; acetonitrile at 0 - 20℃; for 2.16667h; Inert atmosphere;
74%
(R)-3-amino-1-butanol
61477-40-5

(R)-3-amino-1-butanol

C20H20F2N2O6

C20H20F2N2O6

C22H23F2N3O5

C22H23F2N3O5

Conditions
ConditionsYield
With acetic acid In toluene at 80 - 90℃; for 24h;71%
With acetic acid In methanol; toluene at 25 - 90℃; for 24h;61%

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