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Synthetic route

2-benzhydrylsulfanyl-N-hydroxyacetamide
63547-44-4

2-benzhydrylsulfanyl-N-hydroxyacetamide

adrafinil
63547-13-7

adrafinil

Conditions
ConditionsYield
With dihydrogen peroxide; acetic acid at 40℃;72%
1,1-Diphenylmethanol
91-01-0

1,1-Diphenylmethanol

BF3(C2H5)2O

BF3(C2H5)2O

adrafinil
63547-13-7

adrafinil

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 99 percent / trifluoroacetic acid / 3 h / 20 °C
2: 99 percent / H2SO4 / Heating
3: 92 percent / hydroxylamine hydrochloride; KOH / methanol / 0.25 h
4: 72 percent / aq. H2O2; acetic acid / 40 °C
View Scheme
(benzhydrylthio)acetic acid
63547-22-8

(benzhydrylthio)acetic acid

adrafinil
63547-13-7

adrafinil

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 99 percent / H2SO4 / Heating
2: 92 percent / hydroxylamine hydrochloride; KOH / methanol / 0.25 h
3: 72 percent / aq. H2O2; acetic acid / 40 °C
View Scheme
(diphenylmethyl)(ethyl acetate)sulfide
63547-23-9

(diphenylmethyl)(ethyl acetate)sulfide

adrafinil
63547-13-7

adrafinil

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 92 percent / hydroxylamine hydrochloride; KOH / methanol / 0.25 h
2: 72 percent / aq. H2O2; acetic acid / 40 °C
View Scheme
adrafinil
63547-13-7

adrafinil

(meso-1,2-N,N’-bisquinoline-2-methyl-diphenyl-1,2-diamine) zinc(II) trifluoromethanesulfonate

(meso-1,2-N,N’-bisquinoline-2-methyl-diphenyl-1,2-diamine) zinc(II) trifluoromethanesulfonate

C49H45N5O3SZn(1+)

C49H45N5O3SZn(1+)

Conditions
ConditionsYield
In water; acetonitrile pH=6.0; Inert atmosphere;
adrafinil
63547-13-7

adrafinil

C50H45CuN5O4(1+)

C50H45CuN5O4(1+)

C49H45CuN5O3S(1+)

C49H45CuN5O3S(1+)

Conditions
ConditionsYield
In water; acetonitrile pH=6.0; Inert atmosphere;

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