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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

1,4-Phenylenediacetic acid

Cas:7325-46-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

1,4-Phenylenediacetic acid

Cas:7325-46-4

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

1,4-Bis-(carboxymethyl)-benzene

Cas:7325-46-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.

7325-46-4 1,4-Phenylenediacetic acid

Cas:7325-46-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 7325-46-4 with best quality

Cas:7325-46-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after the dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available &diam

1,4-Phenylenediacetic acid CAS7325-46-4

Cas:7325-46-4

Min.Order:1 Kilogram

FOB Price: $7.0 / 10.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

1,4-Phenylenediacetic acid

Cas:7325-46-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Pharmaceutical Intermediate, 1,4-Phenylenediacetic acid CAS:7325-46-4

Cas:7325-46-4

Min.Order:1 Kilogram

FOB Price: $135.0 / 142.0

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:7325-46-4

Cas:7325-46-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Mojin Biotechnology Co.,Ltd

Product quality: Our company have high quality product , and also the product we have good manufacture . First of all, this product is of fine quality. Every finish should be checked by quality inspection system.And every one should be also tried

1,4-Phenylenediacetic acid CAS NO.7325-46-4

Cas:7325-46-4

Min.Order:1 Kilogram

FOB Price: $20.0 / 30.0

Type:Trading Company

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

1,4-Phenylenediacetic Acid

Cas:7325-46-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1,4-Phenylenediacetic acid

Cas:7325-46-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 1.4-Phenylenediacetic acid

Cas:7325-46-4

Min.Order:0 Metric Ton

Negotiable

Type:Other

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Hangzhou Lingrui Chemical Co.,Ltd.

Established in 2010, located in Hangzhou Qinglan science park, lingruichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Our credo is committed to your reliable business partne

1,4-Phenylenediacetic acid

Cas:7325-46-4

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality Appearance:light yellow to beige powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application: 1,4-Phenylenediacetic Acid is an arenedi

1,4-Phenylenediacetic acid

Cas:7325-46-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

1,4-Phenylenediacetic acid Basic information Product Name: 1,4-Phenylenediacetic acid Synonyms: 1,4-Benzenediacetic acid;2,2'-(1,4-Phenylene)diacetic acid;1,4-Phenylenediaceti;Phenyl diacetic acid;1.4-Phenylenediacetic acid, 97% 5GR;4-Phen

1,4-Phenylenediacetic acid

Cas:7325-46-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

1,4-Phenylenediacetic acid

Cas:7325-46-4

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Specification : 1,4-Phenylenediacetic acid CAS N

1,4-Phenylenediacetic acid

Cas:7325-46-4

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

1,4-Phenylenediacetic acid

Cas:7325-46-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

1,4-Phenylenediacetic acid Cas no.7325-46-4 98%

Cas:7325-46-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

1,4-Phenylenediacetic acid

Cas:7325-46-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

P-Phenylenediacetic Acid

Cas:7325-46-4

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

1,4-Phenylenediacetic acid

Cas:7325-46-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

1.4-Phenylenediacetic acid

Cas:7325-46-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:white solid Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as primary an

1,4-Phenylenediacetic acid

Cas:7325-46-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

1,4-Phenylenediacetic acid cas 7325-46-4Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

1,4-Phenylenediacetic acid cas 7325-46-4

Cas:7325-46-4

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Best quality with low priceAppearance:light yellow to beige powder Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

1,4-Phenylenediaceticacid

Cas:7325-46-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SAGECHEM LIMITED

7325-46-4 Application:intermediate

1,4-Benzenediacetic acid

Cas:7325-46-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Yuanye Bio-Technology Co., Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:1g Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any port

1,4-Phenylenediacetic Acid

Cas:7325-46-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

1,4-Phenylenediacetic acid

Cas:7325-46-4

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

1,4-phenylenediacetonitrile
622-75-3

1,4-phenylenediacetonitrile

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

Conditions
ConditionsYield
With hydrogenchloride; acetic acid at 100℃; for 2h;90%
With hydrogenchloride; water at 100℃; for 12h;88%
With hydrogenchloride
carbon monoxide
201230-82-2

carbon monoxide

p-Xylylene dichloride
623-25-6

p-Xylylene dichloride

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

Conditions
ConditionsYield
Stage #1: carbon monoxide With C28H16N2O6Se In butan-1-ol under 750.075 Torr; for 2h; Reflux;
Stage #2: p-Xylylene dichloride With tetrabutylammomium bromide; sodium hydroxide In butan-1-ol at 50℃; under 750.075 Torr; for 24h;
90%
Stage #1: carbon monoxide With C28H22CoN4O6 In butan-1-ol at 60℃; under 760.051 Torr; for 2h; Glovebox; High pressure; Green chemistry;
Stage #2: p-Xylylene dichloride With tetra-(n-butyl)ammonium iodide; sodium hydroxide In butan-1-ol at 60℃; under 760.051 Torr; for 22h; Glovebox; High pressure; Green chemistry; regioselective reaction;
80%
1,4-bis(bromomethyl)benzene
623-24-5

1,4-bis(bromomethyl)benzene

carbon monoxide
201230-82-2

carbon monoxide

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

Conditions
ConditionsYield
With chloro(1,5-cyclooctadiene)rhodium(I) dimer; potassium iodide In formic acid at 90℃; under 760 Torr; for 18h; Carbonylation;89%
1,4-bis(2,2-dibromoethenyl)benzene
77295-67-1

1,4-bis(2,2-dibromoethenyl)benzene

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

Conditions
ConditionsYield
Stage #1: 1,4-bis(2,2-dibromoethenyl)benzene With n-butyllithium In tetrahydrofuran at 0℃; for 1.5h;
Stage #2: With 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane In tetrahydrofuran for 2h;
60%
diethyl 2,2'-(1,4-phenylene)diacetate
36076-26-3

diethyl 2,2'-(1,4-phenylene)diacetate

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

Conditions
ConditionsYield
With sodium hydroxide In ethanol; water for 9h; Heating;57%
carbon monoxide
201230-82-2

carbon monoxide

p-xylylene glycol
589-29-7

p-xylylene glycol

A

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

B

4-tolylacetic acid
622-47-9

4-tolylacetic acid

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); hydrogen iodide In acetone at 90℃; under 68400 Torr; for 42h;A 48%
B 16 % Spectr.
carbon monoxide
201230-82-2

carbon monoxide

p-xylylene glycol
589-29-7

p-xylylene glycol

A

para-xylene
106-42-3

para-xylene

B

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

C

4-tolylacetic acid
622-47-9

4-tolylacetic acid

Conditions
ConditionsYield
With hydrogen iodide; tetrakis(triphenylphosphine) palladium(0) In acetone at 90℃; under 68400 Torr; for 42h; Carbonylation; reduction;A n/a
B 48%
C 16%
octane
111-65-9

octane

para-xylene
106-42-3

para-xylene

n-pentylsodium
1822-71-5

n-pentylsodium

A

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

B

4-tolylacetic acid
622-47-9

4-tolylacetic acid

C

hexanoic acid
142-62-1

hexanoic acid

Conditions
ConditionsYield
Behandlung des Reaktionsprodukts mit festem CO2;
4-acetyl-phenylacetic acid
7398-52-9

4-acetyl-phenylacetic acid

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

Conditions
ConditionsYield
With morpholine; sulfur Erwaermen des Reaktionsprodukts mit aethanol. Kalilauge;
ethyl 4-acetylphenylacetate
1528-42-3

ethyl 4-acetylphenylacetate

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

Conditions
ConditionsYield
With morpholine; sulfur Erwaermen des Reaktionsprodukts mit aethanol. Kalilauge;
para-xylene
106-42-3

para-xylene

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

Conditions
ConditionsYield
With octane; n-pentylsodium anschliessendes Behandeln mit festem Kohlendioxid;
p-phenylene-bis-thioacetic acid diamide

p-phenylene-bis-thioacetic acid diamide

alcoholic potash

alcoholic potash

A

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

B

hydrogen sulfide
7783-06-4

hydrogen sulfide

C

ammonia
7664-41-7

ammonia

p-Xylylene dichloride
623-25-6

p-Xylylene dichloride

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 87 percent / triethylene glycol / 1 h / 90 °C
2: 90 percent / conc. HCl; acetic acid / 2 h / 100 °C
View Scheme
Multi-step reaction with 2 steps
1: aq. ethanol / Heating
2: aq. H2SO4 / Heating
View Scheme
Ethyl 2-phenylethanoate
101-97-3

Ethyl 2-phenylethanoate

butylamine salts

butylamine salts

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 78 percent / SnCl4 / CH2Cl2 / 24 h / Ambient temperature
2: 86 percent / Raney nickel / ethanol / 4 h / Heating
3: 57 percent / sodium hydroxide / ethanol; H2O / 9 h / Heating
View Scheme
diethyl α-methylthio-1,4-benzenediacetate
105077-01-8

diethyl α-methylthio-1,4-benzenediacetate

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 86 percent / Raney nickel / ethanol / 4 h / Heating
2: 57 percent / sodium hydroxide / ethanol; H2O / 9 h / Heating
View Scheme
diethyl 2,2'-(1,4-phenylene)diacetate
36076-26-3

diethyl 2,2'-(1,4-phenylene)diacetate

A

2-(4-(2-ethoxy-2-oxoethyl)phenyl)acetic acid
113520-36-8

2-(4-(2-ethoxy-2-oxoethyl)phenyl)acetic acid

B

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

Conditions
ConditionsYield
With lithium hydroxide monohydrate; water In tetrahydrofuran; ethanol
C10H8O4(2-)*Zn(2+)*C10H8N2*CH4O

C10H8O4(2-)*Zn(2+)*C10H8N2*CH4O

A

4,4'-bipyridine
553-26-4

4,4'-bipyridine

B

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

Conditions
ConditionsYield
With sulfuric acid-d2 In dimethylsulfoxide-d6
1,4-diethynylbenzene
935-14-8

1,4-diethynylbenzene

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

Conditions
ConditionsYield
Stage #1: 1,4-diethynylbenzene With n-butyllithium In tetrahydrofuran at -78℃; for 1h;
Stage #2: With 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane In tetrahydrofuran for 2h;
Stage #3: With oxone In acetone at 50℃; for 12h;
Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere
1.2: 2 h / -78 °C / Inert atmosphere
2.1: oxone||potassium monopersulfate triple salt; water / acetone / 12 h / 50 °C / Inert atmosphere
View Scheme
1,4-bis((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethynyl)benzene

1,4-bis((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethynyl)benzene

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

Conditions
ConditionsYield
With oxone||potassium monopersulfate triple salt; water In acetone at 50℃; for 12h; Inert atmosphere;689 mg
methanol
67-56-1

methanol

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

(4-methoxycarbonylmethylphenyl)acetic acid methyl ester
36076-25-2

(4-methoxycarbonylmethylphenyl)acetic acid methyl ester

Conditions
ConditionsYield
With sulfuric acid Reflux;100%
With sulfuric acid at 80℃; for 94h; Inert atmosphere;90%
With thionyl chloride for 4h; Reflux;85%
ethanol
64-17-5

ethanol

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

(4-methoxycarbonylmethylphenyl)acetic acid methyl ester
36076-25-2

(4-methoxycarbonylmethylphenyl)acetic acid methyl ester

Conditions
ConditionsYield
With sulfuric acid In water at 80℃; for 12h; Inert atmosphere;99%
N(1),N(2)-bis(t-butyloxycarbonyl)-1,2,4-butanetriamine
139024-81-0

N(1),N(2)-bis(t-butyloxycarbonyl)-1,2,4-butanetriamine

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

C38H64N6O10

C38H64N6O10

Conditions
ConditionsYield
With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine In acetonitrile at 0 - 20℃; Reflux;97%
1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

phenylenediacetic acid-2,2,2',2'-d4
104183-03-1

phenylenediacetic acid-2,2,2',2'-d4

Conditions
ConditionsYield
With potassium hydroxide; water-d2 at 160℃; for 28h;95%
1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

2,3-dihydro-1H-isoindole-5,6-dicarboxylic acid 5-{[2-(4-fluoro-phenyl)-ethyl]-amide} 6-(4-methyl-benzylamide)

2,3-dihydro-1H-isoindole-5,6-dicarboxylic acid 5-{[2-(4-fluoro-phenyl)-ethyl]-amide} 6-(4-methyl-benzylamide)

C62H58F2N6O6

C62H58F2N6O6

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 25℃; for 12h;94%
1,2-bis(5-methylisoxazol-3-yl)hydrazine
2632-99-7

1,2-bis(5-methylisoxazol-3-yl)hydrazine

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

zinc(II) acetate dihydrate
5970-45-6

zinc(II) acetate dihydrate

[Zn(μ4-1,4-phenylenediacetate)(μ-4,4′-azobis(pyridine))0.5]n

[Zn(μ4-1,4-phenylenediacetate)(μ-4,4′-azobis(pyridine))0.5]n

Conditions
ConditionsYield
In water at 70 - 120℃; for 72.5h;93%
1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

2-[4-(2-hydroxyethyl)phenyl]ethan-1-ol
5140-03-4

2-[4-(2-hydroxyethyl)phenyl]ethan-1-ol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran Ambient temperature;92%
Stage #1: 1,4-phenylenediacetic acid With dimethyl sulfide borane In tetrahydrofuran for 18h;
Stage #2: With hydrogenchloride In tetrahydrofuran; water
87%
With dimethylsulfide borane complex In tetrahydrofuran at 0 - 20℃; for 24h; Inert atmosphere;81.8%
1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

4'-methoxy-N-(azulen-1-ylmethylene)aniline
854154-95-3

4'-methoxy-N-(azulen-1-ylmethylene)aniline

1,4-bis[(E)-2-(azulen-1-yl)vinyl]benzene

1,4-bis[(E)-2-(azulen-1-yl)vinyl]benzene

Conditions
ConditionsYield
for 10h; Heating;91%
pyrrolidine
123-75-1

pyrrolidine

trimethylsilyl cyanide
7677-24-9

trimethylsilyl cyanide

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

C20H26N4

C20H26N4

Conditions
ConditionsYield
Stage #1: pyrrolidine; 1,4-phenylenediacetic acid With (dimethoxy)methylsilane; molybdenum hexacarbonyl at 65℃;
Stage #2: trimethylsilyl cyanide In 2,2,2-trifluoroethanol at 20℃; for 1h; chemoselective reaction;
91%
ethanol
64-17-5

ethanol

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

diethyl 2,2'-(1,4-phenylene)diacetate
36076-26-3

diethyl 2,2'-(1,4-phenylene)diacetate

Conditions
ConditionsYield
With sulfuric acid for 15h; Reflux;90%
With sulfuric acid at 80℃;87%
With sulfuric acid for 18h; Heating;74%
acetyl chloride for 18h; Heating / reflux;
1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

1,4-benzenediacetaldehyde
39246-00-9

1,4-benzenediacetaldehyde

Conditions
ConditionsYield
With triethylsilane; tris(pentafluorophenyl)borate In benzene at 23℃; for 6h; Schlenk technique; Inert atmosphere;90%
Multi-step reaction with 3 steps
1: 74 percent / aq. H2SO4 / 18 h / Heating
2: 84 percent / LiAlH4 / diethyl ether / 3 h / Heating
3: 62 percent / Dess-Matin periodinane / CH2Cl2 / 4 h / 20 °C
View Scheme
europium(III) nitrate hexahydrate

europium(III) nitrate hexahydrate

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

[(europium(III))2(1,4-phenylenediacetate)3(H2O)] dihydrate

[(europium(III))2(1,4-phenylenediacetate)3(H2O)] dihydrate

Conditions
ConditionsYield
In N,N-dimethyl acetamide; water High Pressure; mixt. of Eu(NO3)3*6H2O (0.4 mmol), H2pda (0.6 mmol), H2O and dimethylacetamide heated in Teflon-lined autoclave at 105°C for 2 d, cooled slowly to room temp.; elem. anal.;90%
yttrium(lll) nitrate hexahydrate

yttrium(lll) nitrate hexahydrate

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

[Y2(1,4-phenylenediacetate)3(H2O)1]*2H2O

[Y2(1,4-phenylenediacetate)3(H2O)1]*2H2O

Conditions
ConditionsYield
In ethanol; water at 180℃; for 1.16667h;90%
1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

(3S,4S)-N3,N4-bis(((1S,2R)-2-phenylcyclopropyl)carbamoyl)pyrrolidine-3,4-dicarboxamide hydrochloride

(3S,4S)-N3,N4-bis(((1S,2R)-2-phenylcyclopropyl)carbamoyl)pyrrolidine-3,4-dicarboxamide hydrochloride

(3S,3’S,4S,4’S)-1,1’-((1,4-phenylene)diacetyl)-bis(N3,N4-bis((1S,2R)-2-phenylcyclopropyl)pyrrolidine-3,4-dicarboxamide)

(3S,3’S,4S,4’S)-1,1’-((1,4-phenylene)diacetyl)-bis(N3,N4-bis((1S,2R)-2-phenylcyclopropyl)pyrrolidine-3,4-dicarboxamide)

Conditions
ConditionsYield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 23℃; for 18h;89%
1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

phenylglyoxylic acid potassium salt
63468-90-6

phenylglyoxylic acid potassium salt

1,4-Phenylene bis(phenylmaleic anhydride)
104595-14-4

1,4-Phenylene bis(phenylmaleic anhydride)

Conditions
ConditionsYield
With acetic anhydride for 1h; Heating;88%
nickel(II) nitrate hexahydrate

nickel(II) nitrate hexahydrate

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

1,3-bis(1H-imidazol-4-yl)benzene
794485-43-1

1,3-bis(1H-imidazol-4-yl)benzene

water
7732-18-5

water

C12H10N4*C10H8O4(2-)*H2O*Ni(2+)

C12H10N4*C10H8O4(2-)*H2O*Ni(2+)

Conditions
ConditionsYield
With sodium hydroxide at 120℃; for 72h; Sealed tube; Autoclave;88%
1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

Diphenylphosphine oxide
4559-70-0

Diphenylphosphine oxide

(1,4-phenylenebis(methylene))bis(diphenylphosphine oxide)
38661-56-2

(1,4-phenylenebis(methylene))bis(diphenylphosphine oxide)

Conditions
ConditionsYield
With sodium persulfate; silver carbonate In acetonitrile at 80℃;88%
1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

1,4-benzenediacetyl dichloride
21062-19-1

1,4-benzenediacetyl dichloride

Conditions
ConditionsYield
With Vilsmeier reagent In toluene at 35 - 40℃; for 0.25h;87%
With thionyl chloride
With phosphorus pentachloride
1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

L-Leu-L-Pro-OMe
72087-28-6

L-Leu-L-Pro-OMe

1,4-phenylenedi(acetyl-L-leucyl-L-proline methyl ester)
668479-44-5

1,4-phenylenedi(acetyl-L-leucyl-L-proline methyl ester)

Conditions
ConditionsYield
Stage #1: 1,4-phenylenediacetic acid With diisopropyl-carbodiimide In dichloromethane for 0.75h;
Stage #2: L-Leu-L-Pro-OMe In dichloromethane for 16h;
86%
gadolinium(III) nitrate hexahydrate

gadolinium(III) nitrate hexahydrate

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

[(gadolinium(III))2(1,4-phenylenediacetate)3(H2O)] dihydrate

[(gadolinium(III))2(1,4-phenylenediacetate)3(H2O)] dihydrate

Conditions
ConditionsYield
In N,N-dimethyl acetamide; water High Pressure; mixt. of Gd(NO3)3*6H2O (0.4 mmol), H2pda (0.6 mmol), H2O and dimethylacetamide heated in Teflon-lined autoclave at 105°C for 2 d, cooled slowly to room temp.; elem. anal.;86%
1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

zinc(II) nitrate hexahydrate

zinc(II) nitrate hexahydrate

4,4'-di(4-pyridyl)stilbene

4,4'-di(4-pyridyl)stilbene

[Zn(1,4-pda)(4,4'-di(4-pyridyl)stilbene)]n

[Zn(1,4-pda)(4,4'-di(4-pyridyl)stilbene)]n

Conditions
ConditionsYield
In water for 72h; Autoclave; High pressure;86%
cobalt(II) chloride hexahydrate

cobalt(II) chloride hexahydrate

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

water
7732-18-5

water

[Co(1,4-phenylenediacetate)(H2O)2]

[Co(1,4-phenylenediacetate)(H2O)2]

Conditions
ConditionsYield
With sodium carbonate In water High Pressure; addn. of aq. soln. of sodium carbonate to aq. soln. of carbon compd., addn. of aq. soln. of cobalt compd. at room temp., sealing in stainless steel reactor, heating at 120°C for 48 h; cooling, isolation of crystals by hand, washing with water, drying over filter paper, elem. anal.;85%
yttrium(lll) nitrate hexahydrate

yttrium(lll) nitrate hexahydrate

europium(III) nitrate hexahydrate

europium(III) nitrate hexahydrate

1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

[Y1.8Eu0.2(1,4-phenylenediacetate)3(H2O)1]*2H2O

[Y1.8Eu0.2(1,4-phenylenediacetate)3(H2O)1]*2H2O

Conditions
ConditionsYield
In ethanol; water at 180℃; for 1.16667h; Milling;85%
1,4-phenylenediacetic acid
7325-46-4

1,4-phenylenediacetic acid

Benzoylformic acid
611-73-4

Benzoylformic acid

1,4-Phenylene bis(phenylmaleic anhydride)
104595-14-4

1,4-Phenylene bis(phenylmaleic anhydride)

Conditions
ConditionsYield
With acetic anhydride; sodium hydride Reflux;85%

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