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Qingdao Beluga Import and Export Co., LTD

5-METHOXY-2,3-DIHYDRO-1H-INDEN-2-AMINE CAS:73305-09-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high qu

5-METHOXY-2,3-DIHYDRO-1H-INDEN-2-AMINE CAS:73305-09-6

Cas:73305-09-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1H-Inden-2-amine,2,3-dihydro-5-methoxy-

Cas:73305-09-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1H-Inden-2-amine,2,3-dihydro-5-methoxy-

Cas:73305-09-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

MEAI from manufacturer

Cas:73305-09-6

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1H-Inden-2-amine,2,3-dihydro-5-methoxy-

Cas:73305-09-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

5-methoxy-2,3-dihydro-1h-inden-2-amine

Cas:73305-09-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

5-METHOXY-2,3-DIHYDRO-1H-INDEN-2-AMINE

Cas:73305-09-6

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

MEAI from manufacturer

Cas:73305-09-6

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

MEAI from manufacturer

Cas:73305-09-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

MEAI from manufacturer

Cas:73305-09-6

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

73305-09-6

Cas:73305-09-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

MEAI from manufacturer

Cas:73305-09-6

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Hebei Mojin Biotechnology Co.,Ltd

1, High quality with competitive price:2, Fast and safe delivery3.Excellent pre-sales and after-sales service4. Well-trained and professional technologist and sales with rich experience in the field for 5-10 yearsAppearance:see detailed specification

1H-Inden-2-amine,2,3-dihydro-5-methoxy-

Cas:73305-09-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates

1H-Inden-2-amine,2,3-dihydro-5-methoxy-

Cas:73305-09-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

METHYL-6-DEOXY-A-D-GLUCOPYRANOSIDE (We are one of a few suppliers that can offer custom synthesis service of this product) We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research.

1H-Inden-2-amine,2,3-dihydro-5-methoxy-

Cas:73305-09-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

1H-Inden-2-amine,2,3-dihydro-5-methoxy-

Cas:73305-09-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

5-METHOXY-2,3-DIHYDRO-1H-INDEN-2-AMINE

Cas:73305-09-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

1H-Inden-2-amine,2,3-dihydro-5-methoxy-

Cas:73305-09-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

MEAI from manufacturer Application:MEAI from manufacturer

MEAI from manufacturer

Cas:73305-09-6

Min.Order:0

Negotiable

Type:Other

inquiry

DB BIOTECH CO., LTD

best seller Application:API

5-METHOXY-2,3-DIHYDRO-1H-INDEN-2-AMINE

Cas:73305-09-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:clear liquid Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as primary a

5-METHOXY-2,3-DIHYDRO-1H-INDEN-2-AMINE

Cas:73305-09-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

5-METHOXY-2,3-DIHYDRO-1H-INDEN-2-AMINE

Cas:73305-09-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers2. Produce products of different specifications and sizes according to your requirements.3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures sta

5-METHOXY-2,3-DIHYDRO-1H-INDEN-2-AMINE

Cas:73305-09-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

73305-09-6

Cas:73305-09-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hunan Longxianng Runhui Trading Co.,Ltd

MEAI from manufacturerAppearance:crystal Storage:stay in dry, cool place and be well-sealed Package:foil bag or as customer's requirment Application:for medical research or Pharmaceutical intermediates Transportation:By express (Door to door) such as

MEAI from manufacturer

Cas:73305-09-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Saiwante (shanghai) New Material Technology Co., Ltd.

Stable supply of goods and provision of high-quality services Application:As raw materials in the field of medicine and biology

MEAI from manufacturer

Cas:73305-09-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hebei Muhuang Technology Co., Ltd

best seller Application:API

5-METHOXY-2,3-DIHYDRO-1H-INDEN-2-AMINE

Cas:73305-09-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

5-METHOXY-2,3-DIHYDRO-1H-INDEN-2-AMINE

Cas:73305-09-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

5-methoxy-2,3-dihydro-1H-inden-2-amine

Cas:73305-09-6

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Hanhong Scientific Co.,Ltd.

factory,reasonable price Appearance:detailed see specifications Storage:Store in dry, dark and ventilated place. Package:according to the clients requirement Application:pharmaceutical intermediates Transportation:by courier,air or sea Port:S

5-Methoxy-2,3-dihydro-1H-inden-2-amine73305-09-6

Cas:73305-09-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

5-(methyloxy)-2,3-dihydro-1H-inden-2-amine hydrochloride
81593-54-6

5-(methyloxy)-2,3-dihydro-1H-inden-2-amine hydrochloride

(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

Conditions
ConditionsYield
With sodium hydroxide In methanol; water at 0 - 25℃; for 3h;95%
5-methoxy-indan-1,2-dione 2-oxime
7235-36-1

5-methoxy-indan-1,2-dione 2-oxime

(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

Conditions
ConditionsYield
Stage #1: 5-methoxy-indan-1,2-dione 2-oxime With sulfuric acid; hydrogen; palladium 10% on activated carbon In acetic acid under 3102.97 Torr; for 18h;
Stage #2: With sodium hydroxide In water at 0℃; pH=10;
37%
Stage #1: 5-methoxy-indan-1,2-dione 2-oxime With sulfuric acid; hydrogen; palladium 10% on activated carbon In acetic acid under 3102.97 Torr; for 18h;
Stage #2: With sodium hydroxide In water at 0℃; pH=10;
37%
With sulfuric acid; hydrogen; acetic acid; palladium on activated charcoal under 3102.97 Torr; for 18h;33%
2-(hydroxyimino)-6-methoxy-2,3-dihydro-1H-inden-1-one
24077-98-3

2-(hydroxyimino)-6-methoxy-2,3-dihydro-1H-inden-1-one

(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

Conditions
ConditionsYield
With sulfuric acid; palladium-carbon; palladium(II) chloride In acetic acid
With sulfuric acid; palladium-carbon; palladium(II) chloride In acetic acid
With sulfuric acid; palladium; acetic acid Hydrogenation;
2-amino-6-methoxy-indan-1-ol; hydrochloride
1071698-32-2

2-amino-6-methoxy-indan-1-ol; hydrochloride

(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

Conditions
ConditionsYield
With sulfuric acid; palladium; acetic acid Hydrogenation;
5-methoxy-1-indanone
5111-70-6

5-methoxy-1-indanone

(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 85 percent / n-butylnitrite; conc. aq. HCl / methanol / 0.5 h / 40 °C
2: H2; H2SO4 / 10percent Pd/C / acetic acid / 7 h / 2585.81 Torr
View Scheme
Multi-step reaction with 2 steps
1: 85 percent / n-butylnitrite; conc. aq. HCl / methanol / 0.5 h / 40 °C
2: H2; H2SO4 / 10 percent Pd/C / acetic acid / 7 h / 2585.74 Torr
View Scheme
Multi-step reaction with 4 steps
1: bromine / ethyl acetate / 0.5 h / 10 - 20 °C
2: N,N-dimethyl-formamide / 2 h / 20 °C
3: hydrazine hydrate / methanol / 6 h / Reflux
4: potassium hydroxide / diethylene glycol dimethyl ether / 2 h / 120 °C
View Scheme
Multi-step reaction with 2 steps
1: hydrogenchloride / methanol / 2 h / 45 °C
2: sulfuric acid; acetic acid; palladium on activated charcoal; hydrogen / 12 h / 25 °C / 775.74 Torr
View Scheme
2-bromo-5-methoxyindan-1-one
29278-11-3

2-bromo-5-methoxyindan-1-one

(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: N,N-dimethyl-formamide / 2 h / 20 °C
2: hydrazine hydrate / methanol / 6 h / Reflux
3: potassium hydroxide / diethylene glycol dimethyl ether / 2 h / 120 °C
View Scheme
C10H13N3O

C10H13N3O

(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

Conditions
ConditionsYield
With potassium hydroxide In diethylene glycol dimethyl ether at 120℃; for 2h;73.44g
(2E)-2-hydroxyimino-5-methoxyindan-1-one

(2E)-2-hydroxyimino-5-methoxyindan-1-one

(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

Conditions
ConditionsYield
With sulfuric acid; palladium on activated charcoal; hydrogen; acetic acid at 25℃; under 775.743 Torr; for 12h;
phthalic anhydride
85-44-9

phthalic anhydride

(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

2-(5-methoxyindane-2-yl)isoindole-1,3,dione
685832-33-1

2-(5-methoxyindane-2-yl)isoindole-1,3,dione

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 125℃; for 96h;68%
2-vinylpyridine
100-69-6

2-vinylpyridine

(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

N,N-bis(2-(2-pyridyl)ethyl)-N-(5-methoxyindan-2-yl)amine

N,N-bis(2-(2-pyridyl)ethyl)-N-(5-methoxyindan-2-yl)amine

Conditions
ConditionsYield
With acetic acid In methanol Heating;30%
(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

5-(methyloxy)-2,3-dihydro-1H-inden-2-amine hydrochloride
81593-54-6

5-(methyloxy)-2,3-dihydro-1H-inden-2-amine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In diethyl ether at 0℃;30%
With hydrogenchloride In water; ethyl acetate pH=1-2;87.86g
2-amino-4-chloro-6-(piperidin-1-yl)-1,3,5-triazine
151898-42-9

2-amino-4-chloro-6-(piperidin-1-yl)-1,3,5-triazine

(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

N-(5-methoxy-indan-2-yl)-6-piperidin-1-yl-[1,3,5]triazine-2,4-diamine

N-(5-methoxy-indan-2-yl)-6-piperidin-1-yl-[1,3,5]triazine-2,4-diamine

Conditions
ConditionsYield
In water at 100℃; for 4h; Substitution;
(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

propionaldehyde
123-38-6

propionaldehyde

5-methoxy-2-(dipropylamino)indan
76413-90-6

5-methoxy-2-(dipropylamino)indan

Conditions
ConditionsYield
With sodium tris(acetoxy)borohydride; triethylamine In 1,2-dichloro-ethane for 24h;1.85 g
(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

(1R,2S)-2-[Bis-(2-pyridin-2-yl-ethyl)-amino]-6-methoxy-indan-1-ol

(1R,2S)-2-[Bis-(2-pyridin-2-yl-ethyl)-amino]-6-methoxy-indan-1-ol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: 30 percent / AcOH / methanol / Heating
2.1: Cu(CF3SO3)2 / methanol / 0.5 h
2.2: 19 percent Chromat. / O2; benzoin; NEt3 / CH2Cl2 / 26 h
View Scheme
(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

(1R,2S)-2-[Bis-(2-pyridin-2-yl-ethyl)-amino]-5-methoxy-indan-1-ol

(1R,2S)-2-[Bis-(2-pyridin-2-yl-ethyl)-amino]-5-methoxy-indan-1-ol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: 30 percent / AcOH / methanol / Heating
2.1: Cu(CF3SO3)2 / methanol / 0.5 h
2.2: 81 percent Chromat. / O2; benzoin; NEt3 / CH2Cl2 / 26 h
View Scheme
(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

5-hydroxy-2-aminoindane

5-hydroxy-2-aminoindane

Conditions
ConditionsYield
With hydrogen bromide
4-chloro-5-methylthieno[2,3-d]pyrimidine
43088-67-1

4-chloro-5-methylthieno[2,3-d]pyrimidine

(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

4-(5-methoxyindan-2-yl)amino-5-methylthieno[2,3-d]pyrimidine

4-(5-methoxyindan-2-yl)amino-5-methylthieno[2,3-d]pyrimidine

Conditions
ConditionsYield
With triethylamine In ethanol
With triethylamine In 5-(furan-2-yl)-4-chlorothieno[2,3-d]pyrimidine; ethanol
(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

(2S)-5-methoxyindan-2-amine

(2S)-5-methoxyindan-2-amine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: triethylamine / dichloromethane / 3 h / 0 - 25 °C
2: potassium hydroxide / water; ethanol / 120 h / 130 °C / Sealed tube
View Scheme
(R)-O-acetylmandeloyl chloride
49845-69-4

(R)-O-acetylmandeloyl chloride

(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

A

(R)-2-(((S)-5-methoxy-2,3-dihydro-1H-indan-2-yl)amino)-2-oxo-1-phenylethyl acetate

(R)-2-(((S)-5-methoxy-2,3-dihydro-1H-indan-2-yl)amino)-2-oxo-1-phenylethyl acetate

B

(R)-2-(((R)-5-methoxy-2,3-dihydro-1H-indan-2-yl)amino)-2-oxo-1-phenylethyl acetate

(R)-2-(((R)-5-methoxy-2,3-dihydro-1H-indan-2-yl)amino)-2-oxo-1-phenylethyl acetate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 25℃; for 3h; Overall yield = 82 %; Overall yield = 1.70 g;
(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

A

(2S)-5-methoxyindan-2-amine

(2S)-5-methoxyindan-2-amine

B

(R)-5-methoxy-2,3-dihydro-1H-indan-2-amine

(R)-5-methoxy-2,3-dihydro-1H-indan-2-amine

Conditions
ConditionsYield
With AD-3_EtOH (DEA), AD Resolution of racemate;A 350 mg
B 220 mg
(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

5-(5-fluoro-3-pyridyl)-N7-[(2R)-5-methoxyindan-2-yl]-N3,N3-dimethylpyrazolo[1,5-a]pyrimidine-3,7-diamine

5-(5-fluoro-3-pyridyl)-N7-[(2R)-5-methoxyindan-2-yl]-N3,N3-dimethylpyrazolo[1,5-a]pyrimidine-3,7-diamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: AD-3_EtOH (DEA), AD / Resolution of racemate
2: N-ethyl-N,N-diisopropylamine / isopropyl alcohol / 12 h / 70 °C
View Scheme
(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

(2R)-2-[[3-(dimethylamino)-5-(5-fluoro-3-pyridyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]indan-5-ol dihydrochloride

(2R)-2-[[3-(dimethylamino)-5-(5-fluoro-3-pyridyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]indan-5-ol dihydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: AD-3_EtOH (DEA), AD / Resolution of racemate
2: N-ethyl-N,N-diisopropylamine / isopropyl alcohol / 12 h / 70 °C
3: hydrogen bromide / water / 2 h / 120 °C / Inert atmosphere
View Scheme
(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

5-(5-fluoro-3-pyridyl)-N7-[(2S)-5-methoxyindan-2-yl]-N3,N3-dimethylpyrazolo[1,5-a]pyrimidine-3,7-diamine

5-(5-fluoro-3-pyridyl)-N7-[(2S)-5-methoxyindan-2-yl]-N3,N3-dimethylpyrazolo[1,5-a]pyrimidine-3,7-diamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: AD-3_EtOH (DEA), AD / Resolution of racemate
2: N-ethyl-N,N-diisopropylamine / isopropyl alcohol / 12 h / 70 °C
View Scheme
(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

(2S)-2-[[3-(dimethylamino)-5-(5-fluoro-3-pyridyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]indan-5-ol

(2S)-2-[[3-(dimethylamino)-5-(5-fluoro-3-pyridyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]indan-5-ol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: AD-3_EtOH (DEA), AD / Resolution of racemate
2: N-ethyl-N,N-diisopropylamine / isopropyl alcohol / 12 h / 70 °C
3: hydrogen bromide / water / 2 h / 120 °C
View Scheme
(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

5-(5-fluoro-3-pyridyl)-N-[(2S)-5-methoxyindan-2-yl]-3-methylpyrazolo[1,5-a]pyrimidin-7-amine

5-(5-fluoro-3-pyridyl)-N-[(2S)-5-methoxyindan-2-yl]-3-methylpyrazolo[1,5-a]pyrimidin-7-amine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: AD-3_EtOH (DEA), AD / Resolution of racemate
2: N-ethyl-N,N-diisopropylamine / isopropyl alcohol / 12 h / 80 °C
View Scheme
(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

(2S)-2-[[5-(5-fluoro-3-pyridyl)-3-methylpyrazolo[1,5-a]pyrimidin-7-yl]amino]indan-5-ol dihydrochloride

(2S)-2-[[5-(5-fluoro-3-pyridyl)-3-methylpyrazolo[1,5-a]pyrimidin-7-yl]amino]indan-5-ol dihydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: AD-3_EtOH (DEA), AD / Resolution of racemate
2: N-ethyl-N,N-diisopropylamine / isopropyl alcohol / 12 h / 80 °C
3: hydrogen bromide / water / 2 h / 120 °C
View Scheme
(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

5-(5-fluoro-3-pyridyl)-3-isopropyl-N-[(2S)-5-methoxyindan-2-yl]pyrazolo[1,5-a]pyrimidin-7-amine

5-(5-fluoro-3-pyridyl)-3-isopropyl-N-[(2S)-5-methoxyindan-2-yl]pyrazolo[1,5-a]pyrimidin-7-amine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: AD-3_EtOH (DEA), AD / Resolution of racemate
2: N-ethyl-N,N-diisopropylamine / isopropyl alcohol / 12 h / 80 °C
View Scheme
(±)-2-amino-5-methoxyindane
73305-09-6

(±)-2-amino-5-methoxyindane

(2S)-2-[[5-(5-fluoro-3-pyridyl)-3-isopropylpyrazolo[1,5-a]pyrimidin-7-yl] amino]indan-5-ol dihydrochloride

(2S)-2-[[5-(5-fluoro-3-pyridyl)-3-isopropylpyrazolo[1,5-a]pyrimidin-7-yl] amino]indan-5-ol dihydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: AD-3_EtOH (DEA), AD / Resolution of racemate
2: N-ethyl-N,N-diisopropylamine / isopropyl alcohol / 12 h / 80 °C
3: hydrogen bromide / water / 2 h / 120 °C
View Scheme

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