As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
Cas:75747-14-7
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inquiryWe can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO
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inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
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inquirychengdu and import and export trade co., LTD., who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do res
WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiryOur advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
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Cas:75747-14-7
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inquiryCompany Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu
TelatinibAppearance:appearance White powder Storage:Dry and ventilated Package:according to customers' requirements Application:Widely used in cosmetics, medicine, beauty health food and other industries Transportation:By air(EMS or EUB or FedEx or T
Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site
Lyander’s R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. Lyander can provide different quantities of cu
Product Name: Telatinib Synonyms: GELDANAMYCIN,17-DEMETHOXY-17-(2-PROPENYLAMINO)-;CP 127374;ALLYLAMINOGELDANAMYCIN;17-(ALLYLAMINO)-17-DEMETHOXYGELDANAMYCIN;17-(ALLYLAMINO)-17-DESMETHOXYGELDANAMYCIN;17-(ALLYLAMINO)-17-DIMETHOXYGELDANAMYCIN;17
Cas:75747-14-7
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inquiryGMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
Cas:75747-14-7
Min.Order:1 Milligram
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Type:Trading Company
inquiryWe are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp
Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe
Cas:75747-14-7
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inquiryWhy is SINOWAY:1) Specialized in pharmaceutical and healthcare industrial since 19872) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days.4) We have warehouse in USA with quickly shipment .5) We can do different t
Stable stock and competitive priceAppearance:powder Storage:available Package:1KG 5KG 25KG Application:As Pharm raw material Transportation:By Courier,Sea or air
high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea
Shanghai Finebiotech Co.,Ltd.was established in 2020, which providing professional chemical services. As a customer-oriented company, we have distinguished ourself from others in providing worldwide customers with cost-effective and efficient service
BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. https:
Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
Cas:75747-14-7
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Type:Lab/Research institutions
inquirygood quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran
17-Aag cas 75747-14-7Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express
factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at 20℃; | 99% |
In chloroform at 20℃; for 18h; | 99% |
In dichloromethane at 23℃; | 95% |
17-allylamino-17-demethoxygeldanamycin
Conditions | Yield |
---|---|
With Dess-Martin periodane In chloroform for 1h; Heating; | 96% |
With Dess-Martin periodane In dichloromethane at 20℃; |
C5H10ClNO*ClH
17-allylamino-17-demethoxygeldanamycin
C5H11NO2*C31H45N3O8*ClH
Conditions | Yield |
---|---|
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite; water In dichloromethane for 0.5h; Stage #2: C5H10ClNO*ClH In dichloromethane for 2h; Stage #3: With water In dichloromethane | 92% |
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite In dichloromethane; water for 0.5h; Stage #2: C5H10ClNO*ClH In dichloromethane for 2h; | 92% |
C3H6ClNO*ClH
17-allylamino-17-demethoxygeldanamycin
C3H7NO2*C31H45N3O8*ClH
Conditions | Yield |
---|---|
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite; water In dichloromethane for 0.5h; Stage #2: C3H6ClNO*ClH In dichloromethane for 2h; Stage #3: With water In dichloromethane | 91% |
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite In dichloromethane; water for 0.5h; Stage #2: C3H6ClNO*ClH In dichloromethane for 2h; | 91% |
17-allylamino-17-demethoxygeldanamycin
(4E,6Z,8S,9S,10E,12S,13R,14S,16R)‐19‐(allylamino)‐13,20,22‐trihydroxy‐8,14‐dimethoxy‐4,10,12,16‐tetramethyl‐3‐oxo‐2‐azabicyclo[1 6.3.1]docosa‐1(22),4,6,10,18,20‐hexaen‐9‐yl carbamate
Conditions | Yield |
---|---|
With sodium dithionite; water In ethyl acetate for 0.5h; | 90% |
With sodium dithionite; water In ethyl acetate at 20℃; for 2h; | 85% |
With sodium dithionite; water In ethyl acetate at 22℃; for 1h; Product distribution / selectivity; | 74% |
β-Alanine acid chloride hydrochloride
17-allylamino-17-demethoxygeldanamycin
C3H7NO2*C31H45N3O8*ClH
Conditions | Yield |
---|---|
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite; water In dichloromethane for 0.5h; Stage #2: β-Alanine acid chloride hydrochloride In dichloromethane for 2h; Stage #3: With water In dichloromethane | 83% |
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite In dichloromethane; water for 0.5h; Stage #2: β-Alanine acid chloride hydrochloride In dichloromethane for 2h; | 83% |
17-allylamino-17-demethoxygeldanamycin
Trichloroacetyl isocyanate
11-carbamate-17-(allylamino)-17-demethoxygeldanamycin
Conditions | Yield |
---|---|
In dichloromethane at 20℃; for 1.5h; | 80% |
dimethylaminoacetyl chloride hydrochloride
17-allylamino-17-demethoxygeldanamycin
C4H9NO2*C31H45N3O8*ClH
Conditions | Yield |
---|---|
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite; water In dichloromethane for 0.5h; Stage #2: dimethylaminoacetyl chloride hydrochloride In dichloromethane for 2h; Stage #3: With water In dichloromethane Product distribution / selectivity; | 79% |
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite In dichloromethane; water for 0.5h; Stage #2: dimethylaminoacetyl chloride hydrochloride In dichloromethane for 2h; | 79% |
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite; water In MeTHF for 0.75h; Stage #2: dimethylaminoacetyl chloride hydrochloride In MeTHF at 0℃; for 3h; Product distribution / selectivity; |
N,N-dimethylaminoacetyl chloride hydrochloride
17-allylamino-17-demethoxygeldanamycin
C4H9NO2*C31H45N3O8*ClH
Conditions | Yield |
---|---|
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite; water In dichloromethane for 0.5h; Stage #2: N,N-dimethylaminoacetyl chloride hydrochloride In dichloromethane for 2h; Stage #3: With water In dichloromethane | 66% |
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite In dichloromethane; water for 0.5h; Stage #2: N,N-dimethylaminoacetyl chloride hydrochloride In dichloromethane for 2h; | 66% |
1-aminocyclopropanecarbonyl chloride hydrochloride
17-allylamino-17-demethoxygeldanamycin
C4H7NO2*C31H45N3O8*ClH
Conditions | Yield |
---|---|
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite; water In dichloromethane for 0.5h; Stage #2: 1-aminocyclopropanecarbonyl chloride hydrochloride In dichloromethane for 2h; Stage #3: With water In dichloromethane | 62% |
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite In dichloromethane; water for 0.5h; Stage #2: 1-aminocyclopropanecarbonyl chloride hydrochloride In dichloromethane for 2h; | 62% |
Ac-Cys-OMe
17-allylamino-17-demethoxygeldanamycin
(R)-methyl-2-acetamido-3-((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-(allylamino)-9-(carbamoyloxy)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-21-ylthio)propanoate
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran at 20℃; | 62% |
With 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran at 20℃; for 2h; | 62% |
C6H10ClNO*ClH
17-allylamino-17-demethoxygeldanamycin
C6H11NO2*C31H45N3O8*ClH
Conditions | Yield |
---|---|
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite; water In dichloromethane for 0.5h; Stage #2: C6H10ClNO*ClH In dichloromethane for 2h; Stage #3: With water In dichloromethane | 60% |
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite In dichloromethane; water for 0.5h; Stage #2: C6H10ClNO*ClH In dichloromethane for 2h; | 60% |
17-allylamino-17-demethoxygeldanamycin
C6H11NO2*C31H45N3O8*ClH
Conditions | Yield |
---|---|
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite; water In dichloromethane for 0.5h; Stage #2: 4-chloro-carbonyl piperidine hydrochloride In dichloromethane for 2h; Stage #3: With water In dichloromethane | 60% |
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite In dichloromethane; water for 0.5h; Stage #2: 4-chloro-carbonyl piperidine hydrochloride In dichloromethane for 2h; | 60% |
N-chlorobetainyl chloride
17-allylamino-17-demethoxygeldanamycin
C5H11NO2*C31H45N3O8*ClH
Conditions | Yield |
---|---|
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite; water In dichloromethane for 0.5h; Stage #2: N-chlorobetainyl chloride In dichloromethane for 2h; Stage #3: With water In dichloromethane | 57% |
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite In dichloromethane; water for 0.5h; Stage #2: N-chlorobetainyl chloride In dichloromethane for 2h; | 57% |
1-methylpiperidine-4-carbonyl chloride hydrochloride
17-allylamino-17-demethoxygeldanamycin
C7H13NO2*C31H45N3O8*ClH
Conditions | Yield |
---|---|
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite; water In dichloromethane for 0.5h; Stage #2: 1-methylpiperidine-4-carbonyl chloride hydrochloride In dichloromethane for 2h; Stage #3: With water In dichloromethane | 56% |
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite In dichloromethane; water for 0.5h; Stage #2: 1-methylpiperidine-4-carbonyl chloride hydrochloride In dichloromethane for 2h; | 56% |
17-allylamino-17-demethoxygeldanamycin
C6H13NO2*C31H45N3O8*ClH
Conditions | Yield |
---|---|
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite; water In dichloromethane for 0.5h; Stage #2: diethylamino-acetyl chloride hydrochloride In dichloromethane for 2h; Stage #3: With water In dichloromethane | 41% |
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite In dichloromethane; water for 0.5h; Stage #2: diethylamino-acetyl chloride hydrochloride In dichloromethane for 2h; | 41% |
17-allylamino-17-demethoxygeldanamycin
Conditions | Yield |
---|---|
With diethylamino-sulfur trifluoride In dichloromethane at -68℃; for 1h; | 35% |
17-allylamino-17-demethoxygeldanamycin
Conditions | Yield |
---|---|
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite; water In ethyl acetate at 20℃; for 0.5h; Stage #2: With hydrogen bromide In ethyl acetate at 0 - 20℃; for 0.5h; | 31% |
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite In water; ethyl acetate at 20℃; for 0.5h; Stage #2: With hydrogen bromide In water; ethyl acetate at 0 - 20℃; for 0.5h; | 31% |
UDP-glucose
17-allylamino-17-demethoxygeldanamycin
Conditions | Yield |
---|---|
With UDP-glycosyltransferase YjiC In aq. buffer at 28℃; for 16h; pH=8; Enzymatic reaction; | 25.5% |
glycinyl chloride hydrochloride
17-allylamino-17-demethoxygeldanamycin
C2H5NO2*C31H45N3O8*ClH
Conditions | Yield |
---|---|
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite In dichloromethane; water for 0.5h; Stage #2: glycinyl chloride hydrochloride In dichloromethane for 2h; | 19% |
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite; water In dichloromethane for 0.5h; Stage #2: glycinyl chloride hydrochloride In dichloromethane for 2h; Stage #3: With water In dichloromethane |
azetidine
isocyanate de chlorosulfonyle
17-allylamino-17-demethoxygeldanamycin
Conditions | Yield |
---|---|
1.) CH2Cl2, 0 deg C, 1 h, 2.) CH2Cl2, from 0 deg C to RT, 1 h; Yield given. Multistep reaction; |
isocyanate de chlorosulfonyle
isopropylamine
17-allylamino-17-demethoxygeldanamycin
Conditions | Yield |
---|---|
1.) CH2Cl2, 0 deg C, 1 h, 2.) CH2Cl2, from 0 deg C to RT, 1 h; Yield given. Multistep reaction; |
17-allylamino-17-demethoxygeldanamycin
Conditions | Yield |
---|---|
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite In dichloromethane; water for 0.5h; Stage #2: With hydrogenchloride In 1,4-dioxane; dichloromethane; water for 0.5h; | |
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite; water In dichloromethane for 0.5h; Stage #2: With hydrogenchloride In 1,4-dioxane; dichloromethane for 0.5h; Product distribution / selectivity; | |
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite; water In ethyl acetate for 1.16667h; Stage #2: With hydrogenchloride In ethyl acetate; acetone at 20℃; for 0.383333h; pH=2.5; Product distribution / selectivity; | |
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite; water In ethyl acetate at 20℃; for 2h; Stage #2: With hydrogenchloride In ethyl acetate at 20℃; for 1.83333h; pH=2; Product distribution / selectivity; | |
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite In dichloromethane; water for 0.5h; Stage #2: With hydrogenchloride In 1,4-dioxane; dichloromethane; water for 0.5h; Inert atmosphere; |
17-allylamino-17-demethoxygeldanamycin
Conditions | Yield |
---|---|
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite; water In tert-butyl methyl ether for 1h; Stage #2: With sulfuric acid In ethanol; tert-butyl methyl ether at -5 - 20℃; for 0.5h; | |
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite In tert-butyl methyl ether; water for 1h; Stage #2: With sulfuric acid In ethanol; tert-butyl methyl ether; water at -5 - 20℃; Inert atmosphere; |
17-allylamino-17-demethoxygeldanamycin
Conditions | Yield |
---|---|
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite; water In dichloromethane for 1h; Stage #2: With phosphoric acid In dichloromethane; isopropyl alcohol for 1h; | |
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite In dichloromethane; water for 1h; Stage #2: With phosphoric acid In dichloromethane; water; isopropyl alcohol Inert atmosphere; |
toluene-4-sulfonic acid
17-allylamino-17-demethoxygeldanamycin
Conditions | Yield |
---|---|
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite; water In dichloromethane for 1h; Stage #2: toluene-4-sulfonic acid In dichloromethane; isopropyl alcohol for 1h; | |
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite In dichloromethane; water for 1h; Stage #2: toluene-4-sulfonic acid In dichloromethane; water; isopropyl alcohol Inert atmosphere; |
Conditions | Yield |
---|---|
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite; water In dichloromethane for 1h; Stage #2: methanesulfonic acid In dichloromethane; isopropyl alcohol for 1h; | |
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite In dichloromethane; water for 1h; Stage #2: methanesulfonic acid In dichloromethane; water; isopropyl alcohol Inert atmosphere; |
(+)-10-camphorsulfonic acid
17-allylamino-17-demethoxygeldanamycin
Conditions | Yield |
---|---|
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite; water In dichloromethane for 1h; Stage #2: (+)-10-camphorsulfonic acid In dichloromethane; isopropyl alcohol for 1h; |
Conditions | Yield |
---|---|
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite; water In dichloromethane for 1h; Stage #2: benzenesulfonic acid In dichloromethane; isopropyl alcohol for 1h; | |
Stage #1: 17-allylamino-17-demethoxygeldanamycin With sodium dithionite In dichloromethane; water for 1h; Stage #2: benzenesulfonic acid In dichloromethane; water; isopropyl alcohol Inert atmosphere; |
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