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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Ethyl 5-oxo-1-phenyl-2-pyrazoline-3-carboxylate

Cas:89-33-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Ethyl 5-oxo-1-phenyl-2-pyrazoline-3-carboxylate

Cas:89-33-8

Min.Order:1

Negotiable

Type:Other

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3-Carbethoxy-1-phenyl-2-pyrazolin-5-one

Cas:89-33-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

89-33-8 Ethyl 5-oxo-1-phenyl-2-pyrazoline-3-carboxylate

Cas:89-33-8

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 89-33-8 with competitive price

Cas:89-33-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1H-Pyrazole-3-carboxylicacid, 4,5-dihydro-5-oxo-1-phenyl-, ethyl ester 89-33-8

Cas:89-33-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Ethyl 5-oxo-1-phenyl-2-pyrazoline-3-carboxylate CAS:89-33-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in h

Ethyl 5-oxo-1-phenyl-2-pyrazoline-3-carboxylate CAS:89-33-8

Cas:89-33-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1H-Pyrazole-3-carboxylicacid, 4,5-dihydro-5-oxo-1-phenyl-, ethyl ester

Cas:89-33-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1H-Pyrazole-3-carboxylicacid, 4,5-dihydro-5-oxo-1-phenyl-, ethyl ester

Cas:89-33-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

Ethyl 5-oxo-1-phenyl-2-pyrazoline-3-carboxylate

Cas:89-33-8

Min.Order:1 Kilogram

FOB Price: $80.0 / 100.0

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Ethyl 5-oxo-1-phenyl-2-pyrazoline-3-carboxylate

Cas:89-33-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Ethyl 5-oxo-1-phenyl-2-pyrazoline-3-carboxylate

Cas:89-33-8

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Ethyl 5-oxo-1-phenyl-2-pyrazoline-3-carboxylate

Cas:89-33-8

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

1-PHENYL-3-CARBOETHOXY-5-PYRAZOLONE

Cas:89-33-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1H-Pyrazole-3-carboxylicacid, 4,5-dihydro-5-oxo-1-phenyl-, ethyl ester

Cas:89-33-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Ethyl 5-oxo-1-phenyl-2-pyrazoline-3-carboxylate

Cas:89-33-8

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

Ethyl 5-oxo-1-phenyl-2-pyrazoline-3-carboxylate

Cas:89-33-8

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

superior quality Appearance:Pale Yellow Solid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Used in synthetic C.I. pigment red 38, 39, 42 variet

1H-Pyrazole-3-carboxylicacid, 4,5-dihydro-5-oxo-1-phenyl-, ethyl ester

Cas:89-33-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung, LG, Merck, Thermo Fisher Scientific and so o

89-33-8

Cas:89-33-8

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Ethyl 5-oxo-1-phenyl-2-pyrazoline-3-carboxylate Basic information Product Name: Ethyl 5-oxo-1-phenyl-2-pyrazoline-3-carboxylate Synonyms: 1-Phenyl-5-oxo-2-pyrazoline-3-carboxylicacid,ethylester;4,5-dihydro-5-oxo-1-phenyl-1h-pyrazole-3-carboxyli

Ethyl 5-oxo-1-phenyl-2-pyrazoline-3-carboxylate

Cas:89-33-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

1-Phenyl-3-Carboethoxy-5-Pyrazolone

Cas:89-33-8

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

1-Phenyl-3-Carboethoxy-5-Pyrazolone

Cas:89-33-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

1-Phenyl-3-Carboethoxy-5-Pyrazolone

Cas:89-33-8

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

Ethyl 5-oxo-1-phenyl-2-pyrazoline-3-carboxylate

Cas:89-33-8

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

Ethyl 1-phenyl-5-pyrazolinone-3-carboxylate

Cas:89-33-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

1,2,4,5-Benzenetetracarboxylic anhydride

Cas:89-33-8

Min.Order:0

Negotiable

Type:Other

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec Ethyl 5-oxo-1-phenyl-4,5-dihydro-1H-pyrazole-3-carboxylate 250mg

Cas:89-33-8

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

Ethyl 5-Oxo-1-Phenyl-2-Pyrazoline-3-Carboxylate

Cas:89-33-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

3-(Ethoxycarbonyl)-1-phenyl-5-pyrazolone

Cas:89-33-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

Ethyl 5-oxo-1-phenyl-2-pyrazoline-3-carboxylate

Cas:89-33-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

C6H6N2*(x)ClH

C6H6N2*(x)ClH

acetylenedicarboxylic acid diethyl ester
762-21-0

acetylenedicarboxylic acid diethyl ester

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

Conditions
ConditionsYield
Stage #1: C6H6N2*(x)ClH With sodium acetate In ethanol; water at 20℃; for 0.0833333h;
Stage #2: acetylenedicarboxylic acid diethyl ester In ethanol; water for 3h; Reflux;
C16H9BrFNOS

C16H9BrFNOS

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(2-bromo-6-fluorophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(2-bromo-6-fluorophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C16H9BrFNOS; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With quinine In dichloromethane at 30℃; for 24h; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; for 0.5h; Michael Addition; enantioselective reaction;
96%
C16H10N2O3S

C16H10N2O3S

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(4-nitrophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(4-nitrophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C16H10N2O3S; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With potassium carbonate In dichloromethane at 20℃; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; Michael Addition;
96%
C16H10ClNOS

C16H10ClNOS

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(3-chlorophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(3-chlorophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C16H10ClNOS; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With quinine In dichloromethane at 30℃; for 24h; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; for 0.5h; Michael Addition; enantioselective reaction;
95%
C16H10FNOS

C16H10FNOS

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(2-fluorophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(2-fluorophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C16H10FNOS; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With quinine In dichloromethane at 30℃; for 24h; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; for 0.5h; Michael Addition; enantioselective reaction;
94%
C16H10FNOS

C16H10FNOS

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(2-fluorophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(2-fluorophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C16H10FNOS; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With potassium carbonate In dichloromethane at 20℃; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; Michael Addition;
94%
C16H10FNOS

C16H10FNOS

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(3-fluorophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(3-fluorophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C16H10FNOS; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With quinine In dichloromethane at 30℃; for 24h; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; for 0.5h; Michael Addition; enantioselective reaction;
94%
C16H10N2O3S

C16H10N2O3S

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(4-nitrophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(4-nitrophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C16H10N2O3S; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With quinine In dichloromethane at 30℃; for 24h; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; for 0.5h; Michael Addition; enantioselective reaction;
93%
C17H13NOS

C17H13NOS

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(m-tolyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(m-tolyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C17H13NOS; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With quinine In dichloromethane at 30℃; for 24h; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; for 0.5h; Michael Addition; enantioselective reaction;
92%
C16H10FNOS

C16H10FNOS

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(3-fluorophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(3-fluorophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C16H10FNOS; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With potassium carbonate In dichloromethane at 20℃; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; Michael Addition;
91%
C16H10BrNOS

C16H10BrNOS

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(4-bromophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(4-bromophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C16H10BrNOS; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With quinine In dichloromethane at 30℃; for 24h; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; for 0.5h; Michael Addition; enantioselective reaction;
91%
5-benzylidene thiazolone
92795-17-0

5-benzylidene thiazolone

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(phenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(phenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: 5-benzylidene thiazolone; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With quinine In dichloromethane at 30℃; for 24h; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; for 0.5h; Reagent/catalyst; Solvent; Michael Addition; enantioselective reaction;
91%
C16H10ClNOS

C16H10ClNOS

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(3-chlorophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(3-chlorophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C16H10ClNOS; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With potassium carbonate In dichloromethane at 20℃; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; Michael Addition;
90%
C16H9BrFNOS

C16H9BrFNOS

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(2-bromo-6-fluorophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(2-bromo-6-fluorophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C16H9BrFNOS; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With potassium carbonate In dichloromethane at 20℃; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; Michael Addition;
90%
5-benzylidene thiazolone
92795-17-0

5-benzylidene thiazolone

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(phenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(phenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: 5-benzylidene thiazolone; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With potassium carbonate In dichloromethane at 20℃; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; Michael Addition;
89%
C16H10FNOS

C16H10FNOS

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(4-fluorophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(4-fluorophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C16H10FNOS; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With potassium carbonate In dichloromethane at 20℃; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; Michael Addition;
88%
C17H13NOS

C17H13NOS

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(p-tolyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(p-tolyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C17H13NOS; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With potassium carbonate In dichloromethane at 20℃; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; Michael Addition;
87%
C16H10BrNOS

C16H10BrNOS

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(4-bromophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(4-bromophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C16H10BrNOS; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With potassium carbonate In dichloromethane at 20℃; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; Michael Addition;
86%
C18H15NOS

C18H15NOS

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(2,4-dimethylphenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(2,4-dimethylphenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C18H15NOS; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With potassium carbonate In dichloromethane at 20℃; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; Michael Addition;
85%
5-benzylidene thiazolone
92795-17-0

5-benzylidene thiazolone

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(phenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(phenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: 5-benzylidene thiazolone; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With 3-(3,5-bis(trifluoromethyl)anilino)-4-([(1R,2R)-2-(piperidin-1-yl)cyclohexyl]amino)cyclobut-3-ene-1,2-dione In dichloromethane at 30℃; for 24h; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; for 0.5h; Michael Addition; enantioselective reaction;
85%
C16H10FNOS

C16H10FNOS

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(4-fluorophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(4-fluorophenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C16H10FNOS; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With quinine In dichloromethane at 30℃; for 24h; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; for 0.5h; Michael Addition; enantioselective reaction;
83%
C17H13NOS

C17H13NOS

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(m-tolyl)methyl)-1-phenyl-1H- pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(m-tolyl)methyl)-1-phenyl-1H- pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C17H13NOS; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With potassium carbonate In dichloromethane at 20℃; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; Michael Addition;
83%
C22H15NOS

C22H15NOS

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 4-([1,1'-biphenyl]-4-yl(4-acetoxy-2-phenylthiazol-5-yl)methyl)-5-acetoxy-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 4-([1,1'-biphenyl]-4-yl(4-acetoxy-2-phenylthiazol-5-yl)methyl)-5-acetoxy-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C22H15NOS; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With quinine In dichloromethane at 30℃; for 24h; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; for 0.5h; Michael Addition; enantioselective reaction;
81%
C17H13NOS

C17H13NOS

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(o-tolyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(o-tolyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C17H13NOS; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With quinine In dichloromethane at 30℃; for 24h; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; for 0.5h; Michael Addition; enantioselective reaction;
80%
C22H15NOS

C22H15NOS

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 4-([1,1'-biphenyl]-4-yl(4-acetoxy-2-phenylthiazol-5-yl)methyl)-5-acetoxy-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 4-([1,1'-biphenyl]-4-yl(4-acetoxy-2-phenylthiazol-5-yl)methyl)-5-acetoxy-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C22H15NOS; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With potassium carbonate In dichloromethane at 20℃; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; Michael Addition;
79%
C17H13NOS

C17H13NOS

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(o-tolyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(o-tolyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C17H13NOS; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With potassium carbonate In dichloromethane at 20℃; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; Michael Addition;
79%
N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-chloro-4-formyl-1-phenyl-1H-pyrazole-3-carboxylate
38405-71-9

ethyl 5-chloro-4-formyl-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
With trichlorophosphate at 10 - 70℃; Vilsmeier-Haack reaction;78%
C18H15NOS

C18H15NOS

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(2,4-dimethylphenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(2,4-dimethylphenyl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C18H15NOS; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With quinine In dichloromethane at 30℃; for 24h; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; for 0.5h; Michael Addition; enantioselective reaction;
78%
C20H13NOS

C20H13NOS

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(naphthalen-2-yl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(naphthalen-2-yl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C20H13NOS; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With quinine In dichloromethane at 30℃; for 24h; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; for 0.5h; Michael Addition; enantioselective reaction;
75%
C20H13NOS

C20H13NOS

acetyl chloride
75-36-5

acetyl chloride

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(naphthalen-2-yl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 5-acetoxy-4-((4-acetoxy-2-phenylthiazol-5-yl)(naphthalen-2-yl)methyl)-1-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: C20H13NOS; 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one With potassium carbonate In dichloromethane at 20℃; Michael Addition;
Stage #2: acetyl chloride In dichloromethane at 0℃; Michael Addition;
71%
2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one
89-33-8

2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one

[1-chloro-2,2,2-trifluoro-1-(4-methoxy-phenyl)-ethyl]-p-tolyl-carbodiimide

[1-chloro-2,2,2-trifluoro-1-(4-methoxy-phenyl)-ethyl]-p-tolyl-carbodiimide

4-(4-methoxy-phenyl)-1-phenyl-6-p-tolylimino-4-trifluoromethyl-1,4,5,6-tetrahydro-pyrazolo[4,3-e][1,3]oxazine-3-carboxylic acid ethyl ester

4-(4-methoxy-phenyl)-1-phenyl-6-p-tolylimino-4-trifluoromethyl-1,4,5,6-tetrahydro-pyrazolo[4,3-e][1,3]oxazine-3-carboxylic acid ethyl ester

Conditions
ConditionsYield
Stage #1: 2,4-dihydro-2-phenyl-5-ethoxycarbonyl-3H-pyrazol-3-one; [1-chloro-2,2,2-trifluoro-1-(4-methoxy-phenyl)-ethyl]-p-tolyl-carbodiimide With triethylamine In benzene at 20℃; for 2h;
Stage #2: In benzene for 2h; Heating;
53%

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