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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

5-Bromo-2-methyl-3-nitropyridine Manufacturer/High quality/Best price/In stock

Cas:911434-05-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Wuhan Fortuna Chemical Co.,Ltd

Factory supply 5-Bromo-2-methyl-3-nitropyridine CAS 911434-05-4 with fast delivery Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediat

Factory supply 5-Bromo-2-methyl-3-nitropyridine CAS 911434-05-4 with fast delivery

Cas:911434-05-4

Min.Order:10 Kilogram

FOB Price: $10.0

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 5-Bromo-2-Methyl-3-Nitropyridine

Cas:911434-05-4

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality Oled CAS 911434-05-4 Pyridine,5-bromo-2-methyl-3-nitro-

Cas:911434-05-4

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

5-Bromo-2-methyl-3-nitropyridine

Cas:911434-05-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com/pro01en/id/1664.html Product Name 5-Bromo-2-methyl-3-nitropyridine

5-Bromo-2-methyl-3-nitropyridine

Cas:911434-05-4

Min.Order:1 Gram

FOB Price: $2.0

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

5-Bromo-2-methyl-3-nitropyridine Basic information Product Name: 5-Bromo-2-methyl-3-nitropyridine Synonyms: 5-Bromo-2-methyl-3-nitropyridine;5-Bromo-3-nitropicoline;5-Bromo-2-methyl-3-ni

5-Bromo-2-methyl-3-nitropyridine

Cas:911434-05-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

5-Bromo-2-methyl-3-nitropyridine

Cas:911434-05-4

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 911434-05-4 with best quality

Cas:911434-05-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Pyridine,5-bromo-2-methyl-3-nitro- 911434-05-4

Cas:911434-05-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

Product Name: 5-Bromo-2-methyl-3-nitropyridine CAS: 911434-05-4 MF: C6H5BrN2O2 MW: 217.02 EINECS: 200-258-5 Mol File: 911434-05-4.mol 5-Bromo-2-methyl-3-nitropyridine Structure 5-Bromo-2-methyl-3-nitropyridine Chemical Properties

5-Bromo-2-methyl-3-nitropyridine

Cas:911434-05-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

5-Bromo-2-methyl-3-nitropyridine CAS:911434-05-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high qualit

5-Bromo-2-methyl-3-nitropyridine CAS:911434-05-4

Cas:911434-05-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Pyridine,5-bromo-2-methyl-3-nitro-

Cas:911434-05-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Pyridine,5-bromo-2-methyl-3-nitro-/ LIDE PHARMA- Factory supply / Best price

Cas:911434-05-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

5-Bromo-2-methyl-3-nitropyridine

Cas:911434-05-4

Min.Order:1 Kilogram

FOB Price: $50.0 / 100.0

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

5-Bromo-2-Methyl-3-Nitropyridine

Cas:911434-05-4

Min.Order:0

Negotiable

Type:Manufacturers

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Triumph International Development Limilted

Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By Se

5-Bromo-2-methyl-3-nitropyridine

Cas:911434-05-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

5-Bromo-2-methyl-3-nitropyridine

Cas:911434-05-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

5-bromo-2-methyl-3-nitropyridine

Cas:911434-05-4

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

5-Bromo-2-methyl-3-nitropyridine

Cas:911434-05-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

5-Bromo-2-methyl-3-nitropyridine

Cas:911434-05-4

Min.Order:1 Gram

Negotiable

Type:Other

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 5-Bromo-2-Methyl-3-Nitropyridine

Cas:911434-05-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality Appearance:powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Used as Pharmaceutical Intermediates Transportation:BY AIR Port

5-Bromo-2-methyl-3-nitropyridine

Cas:911434-05-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Siwei Development Group Ltd.

Product name: 5-Bromo-2-Methyl-3-Nitropyridine CAS No.:911434-05-4 Molecule Formula:C6H5BrN2O2 Molecule Weight:217.02 Purity: 97.0% Package: 25kg/drum Description:Yellow powder Manufacture Standards:Enterprise Standard TESTING IT

High Quality 5-Bromo-2-Methyl-3-Nitropyridine in stock

Cas:911434-05-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China with ISO certificate, Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED

Pyridine,5-bromo-2-methyl-3-nitro-CAS NO.: 911434-05-4

Cas:911434-05-4

Min.Order:1 Gram

FOB Price: $2.0

Type:Lab/Research institutions

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Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Best Offer5-Bromo-2-methyl-3-nitropyridine

Cas:911434-05-4

Min.Order:0

Negotiable

Type:Trading Company

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

5-Bromo-2-methyl-3-nitropyridine

Cas:911434-05-4

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

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Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

5-Bromo-2-methyl-3-nitropyridine

Cas:911434-05-4

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

5-Bromo-2-methyl-3-nitropyridine

Cas:911434-05-4

Min.Order:0

Negotiable

Type:Trading Company

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

5-Bromo-2-methyl-3-nitropyridine

Cas:911434-05-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

2-(5-bromo-3-nitro-pyridin-2-yl)-malonic acid diethyl ester
911434-04-3

2-(5-bromo-3-nitro-pyridin-2-yl)-malonic acid diethyl ester

5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

Conditions
ConditionsYield
With hydrogenchloride; water for 5h; Heating / reflux;96%
With hydrogenchloride In water Reflux;95%
With hydrogenchloride; water for 5h; Reflux;89.7%
5-bromo-2-chloro-3-nitropyridine
67443-38-3

5-bromo-2-chloro-3-nitropyridine

diethyl malonate
105-53-3

diethyl malonate

5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

Conditions
ConditionsYield
Stage #1: 5-bromo-2-chloro-3-nitropyridine; diethyl malonate With sodium hydride In tetrahydrofuran at 20℃; for 3.5h;
Stage #2: With hydrogenchloride; water Heating / reflux;
Stage #3: With water; sodium carbonate pH=9;
63.3%
Stage #1: 5-bromo-2-chloro-3-nitropyridine; diethyl malonate With sodium hydride In tetrahydrofuran at 20℃; for 3.5h;
Stage #2: With hydrogenchloride; water Heating / reflux;
Stage #3: With sodium carbonate pH=9;
63.3%
Stage #1: 5-bromo-2-chloro-3-nitropyridine; diethyl malonate With sodium hydride In tetrahydrofuran at 20℃; for 3.5h;
Stage #2: With hydrogenchloride; water Heating / reflux;
Stage #3: With water; sodium carbonate pH=9;
63.3%
Stage #1: diethyl malonate With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 0.333333h;
Stage #2: 5-bromo-2-chloro-3-nitropyridine In N,N-dimethyl-formamide; mineral oil at 20 - 40℃; for 1.5h;
Stage #3: With hydrogenchloride In water at 100℃; for 13h;
Stage #1: diethyl malonate With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃;
Stage #2: 5-bromo-2-chloro-3-nitropyridine at 20 - 40℃; for 1.5h;
5-bromo-2-chloro-3-nitropyridine
67443-38-3

5-bromo-2-chloro-3-nitropyridine

5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium hydride / N,N-dimethyl-formamide / 40 °C / Inert atmosphere
2: hydrogenchloride / water / 110 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1.1: sodium hydride / N,N-dimethyl-formamide / 0 - 20 °C
1.2: 2 h / 100 °C
2.1: hydrogenchloride; water / 18 h / Reflux
2.2: 0 °C
View Scheme
Multi-step reaction with 2 steps
1.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 - 20 °C
1.2: 2 h / 100 °C
2.1: hydrogenchloride; water / 18 h / Reflux
2.2: 0 °C
View Scheme
5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

N,N-dimethyl-formamide dimethyl acetal
4637-24-5

N,N-dimethyl-formamide dimethyl acetal

(E)-2-(5-bromo-3-nitropyridin-2-yl)-N,N-dimethylethen-1-amine
1229457-88-8

(E)-2-(5-bromo-3-nitropyridin-2-yl)-N,N-dimethylethen-1-amine

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 90℃; for 4h;98%
In N,N-dimethyl-formamide at 90℃; for 4h;76%
In N,N-dimethyl-formamide at 20 - 90℃; for 7.5h; Large scale;
5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzamide

4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzamide

N-(6-methyl-5-nitropyridin-3-yl)-4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzamide

N-(6-methyl-5-nitropyridin-3-yl)-4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzamide

Conditions
ConditionsYield
With potassium carbonate; rac-diaminocyclohexane; copper(I) bromide In toluene at 90 - 100℃; Reagent/catalyst; Solvent; Inert atmosphere;96.3%
5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

N,N-dimethyl-formamide dimethyl acetal
4637-24-5

N,N-dimethyl-formamide dimethyl acetal

2-(5-bromo-3-nitropyridin-2-yl)-N,N-dimethylethenamine
1227628-14-9

2-(5-bromo-3-nitropyridin-2-yl)-N,N-dimethylethenamine

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 90℃; for 4.25h; Inert atmosphere;95.2%
In N,N-dimethyl-formamide at 90℃; for 0.25h;95.2%
In N,N-dimethyl-formamide at 10℃; for 5h;
In N,N-dimethyl-formamide at 100℃; for 1h;
tert-butyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
877399-74-1

tert-butyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

tert-butyl 4-[4-(6-methyl-5-nitropyridin-3-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate
1229457-95-7

tert-butyl 4-[4-(6-methyl-5-nitropyridin-3-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: 5-bromo-2-methyl-3-nitropyridine; tetrakis(triphenylphosphine) palladium(0) In 1,2-dimethoxyethane at 20℃; for 0.333333h;
Stage #2: tert-butyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate With potassium carbonate In 1,2-dimethoxyethane; isopropyl alcohol at 20 - 85℃;
95%
(4,4,5,5-tetramethyl-2-[4-(methylsulfonyl)phenyl])-1,3,2-dioxaborolane
603143-27-7

(4,4,5,5-tetramethyl-2-[4-(methylsulfonyl)phenyl])-1,3,2-dioxaborolane

5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

2-methyl-3-nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
1353715-51-1

2-methyl-3-nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

Conditions
ConditionsYield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate In 1,4-dioxane at 80℃; for 12h; Inert atmosphere;94%
5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

trimethylsilylacetylene
1066-54-2

trimethylsilylacetylene

2-methyl-3-nitro-5-[(trimethylsilyl)ethynyl]pyridine
1228962-69-3

2-methyl-3-nitro-5-[(trimethylsilyl)ethynyl]pyridine

Conditions
ConditionsYield
With triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide at 80℃; for 4h;91%
N,N-Dimethylpropargylamin
7223-38-3

N,N-Dimethylpropargylamin

5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

N,N-dimethyl-3-(6-methyl-5-nitropyridin-3-yl)prop-2-yn-1-amine
1286218-46-9

N,N-dimethyl-3-(6-methyl-5-nitropyridin-3-yl)prop-2-yn-1-amine

Conditions
ConditionsYield
With diethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide In N,N-dimethyl-formamide at 20℃; for 15h; Product distribution / selectivity;91%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine at 20℃; Darkness; Reflux;91%
5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

5-bromo-2-methylpyridin-3-ylamine
914358-73-9

5-bromo-2-methylpyridin-3-ylamine

Conditions
ConditionsYield
With hydrogenchloride; iron In methanol; water for 2h; Reflux;90%
With iron; ammonium chloride In ethanol; water at 90℃; for 0.666667h;90%
With iron; ammonium chloride In ethanol; water at 90℃; for 0.666667h;90%
5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

N-tert-Butoxycarbonyl-1-amino-3-propyne
92136-39-5

N-tert-Butoxycarbonyl-1-amino-3-propyne

tert-butyl [3-(6-methyl-5-nitropyridin-3-yl)prop-2-yn-1-yl]carbamate
1228962-84-2

tert-butyl [3-(6-methyl-5-nitropyridin-3-yl)prop-2-yn-1-yl]carbamate

Conditions
ConditionsYield
With triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide at 70℃; for 2.5h; Inert atmosphere;79%
1-methyl-piperazine
109-01-3

1-methyl-piperazine

5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

1-methyl-4-(6-methyl-5-nitropyridin-3-yl)piperazine
1228962-94-4

1-methyl-4-(6-methyl-5-nitropyridin-3-yl)piperazine

Conditions
ConditionsYield
With caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; bis(dibenzylideneacetone)-palladium(0) In 1,4-dioxane at 150℃; for 22h; sealed tube; Inert atmosphere;71%
5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

C16H27BO

C16H27BO

5-(2-(cyclohex-3-en-1-yl)ethyl)-2-methyl-3-nitropyridine

5-(2-(cyclohex-3-en-1-yl)ethyl)-2-methyl-3-nitropyridine

Conditions
ConditionsYield
With dichloro[1,1'-bis(di-t-butylphosphino)ferrocene]palladium(II); triethylamine In water at 45℃; Suzuki-Miyaura Coupling; Inert atmosphere; Schlenk technique; Sealed tube;67%
5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

bis(pinacol)diborane
73183-34-3

bis(pinacol)diborane

2-methyl-3-nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
1353715-51-1

2-methyl-3-nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

Conditions
ConditionsYield
With potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride In 1,4-dioxane at 100℃; for 1.5h; Microwave irradiation;66%
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate In 1,4-dioxane at 100℃; for 6h; Inert atmosphere;
5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

C14H27BO2

C14H27BO2

5-(2-(t-butoxy)ethyl)-2-methyl-3-nitropyridine

5-(2-(t-butoxy)ethyl)-2-methyl-3-nitropyridine

Conditions
ConditionsYield
With dichloro[1,1'-bis(di-t-butylphosphino)ferrocene]palladium(II); triethylamine In water at 45℃; Suzuki-Miyaura Coupling; Inert atmosphere; Schlenk technique; Sealed tube;64%
5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

tert-butyl 3,3-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,6-dihydropyridine-1-carboxylate
1228962-22-8

tert-butyl 3,3-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,6-dihydropyridine-1-carboxylate

tert-butyl 3',3',6-trimethyl-5-nitro-3',6'-dihydro-3,4'-bipyridine-1'(2'H)-carboxylate
1228962-23-9

tert-butyl 3',3',6-trimethyl-5-nitro-3',6'-dihydro-3,4'-bipyridine-1'(2'H)-carboxylate

Conditions
ConditionsYield
With potassium phosphate; tetrakis(triphenylphosphine) palladium(0) In 1,4-dioxane; water at 80℃; for 24h; Inert atmosphere;60%
5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

N,N-dimethyl-formamide dimethyl acetal
4637-24-5

N,N-dimethyl-formamide dimethyl acetal

6-bromo-1H-pyrrolo[3,2-b]pyrridine
944937-53-5

6-bromo-1H-pyrrolo[3,2-b]pyrridine

Conditions
ConditionsYield
Stage #1: 5-bromo-2-methyl-3-nitropyridine; N,N-dimethyl-formamide dimethyl acetal In N,N-dimethyl-formamide at 100℃; for 1h;
Stage #2: With iron; acetic acid at 100℃; for 20h; Inert atmosphere;
60%
1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl )-1,2,3,6-tetrahydropyridine
454482-11-2

1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl )-1,2,3,6-tetrahydropyridine

5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

C12H15N3O2

C12H15N3O2

Conditions
ConditionsYield
With potassium phosphate; tetrakis(triphenylphosphine) palladium(0) In 1,4-dioxane; water at 80℃; Inert atmosphere;56%
5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

tert-butyl 4-methylidenepiperidine-1-carboxylate
159635-49-1

tert-butyl 4-methylidenepiperidine-1-carboxylate

tert-butyl 4-[(6-methyl-5-nitro-3-pyridyl)methylene]piperidine-1-carboxylate

tert-butyl 4-[(6-methyl-5-nitro-3-pyridyl)methylene]piperidine-1-carboxylate

Conditions
ConditionsYield
With potassium acetate; palladium diacetate; triphenylphosphine In N,N-dimethyl-formamide at 100℃; Sealed tube;42%
5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

3-ethynyloxetan-3-ol
1352492-38-6

3-ethynyloxetan-3-ol

3-[2-(6-methyl-5-nitro-3-pyridyl)ethynyl]oxetan-3-ol

3-[2-(6-methyl-5-nitro-3-pyridyl)ethynyl]oxetan-3-ol

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine at 20℃;40%
5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

vinyl magnesium bromide
1826-67-1

vinyl magnesium bromide

4-bromo-7-methyl-1H-pyrrolo[2,3-c]pyridine

4-bromo-7-methyl-1H-pyrrolo[2,3-c]pyridine

Conditions
ConditionsYield
In tetrahydrofuran at -50 - -40℃; for 0.5h; Inert atmosphere;36.6%
In tetrahydrofuran at -50 - -40℃; for 0.5h; Inert atmosphere;36.6%
5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

(2,2'-bipyride-kN1,kN1')(1,1,1-trifluoromethanethiolato-kS)-copper
1413732-47-4

(2,2'-bipyride-kN1,kN1')(1,1,1-trifluoromethanethiolato-kS)-copper

2-methyl-3-nitro-5-[(trifluoromethyl)thio]pyridine

2-methyl-3-nitro-5-[(trifluoromethyl)thio]pyridine

Conditions
ConditionsYield
In 1,4-dioxane at 110℃; for 15h; Inert atmosphere;23%
5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

5-bromo-3-nitropicolinic acid
954240-89-2

5-bromo-3-nitropicolinic acid

Conditions
ConditionsYield
With potassium permanganate In acetonitrile at 80 - 100℃;2.4%
5-ethynylpyrimidine-2-amine
857265-74-8

5-ethynylpyrimidine-2-amine

5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

5-(6-methyl-5-nitro-pyridin-3-ylethynyl)-pyrimidin-2-ylamine
911434-06-5

5-(6-methyl-5-nitro-pyridin-3-ylethynyl)-pyrimidin-2-ylamine

Conditions
ConditionsYield
With triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide In N,N-dimethyl-formamide at 60℃; for 3h;
5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

N-(6-(5-(4-methoxyphenylsulfonamido)-6-methylpyridin-3-yl)benzo[d]thiazol-2-yl)acetamide
1112980-38-7

N-(6-(5-(4-methoxyphenylsulfonamido)-6-methylpyridin-3-yl)benzo[d]thiazol-2-yl)acetamide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: water; iron; acetic acid / 1.25 h / 20 °C / Inert atmosphere; Cooling
2: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; potassium carbonate / 1,2-dimethoxyethane; water / 1.33 h / 100 °C / Inert atmosphere
3: pyridine; dmap / tetrahydrofuran / 6 h / 65 °C / Inert atmosphere
View Scheme
5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

6-bromo-1H-pyrazolo[4,3-b]pyridine
1150617-54-1

6-bromo-1H-pyrazolo[4,3-b]pyridine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: hydrogenchloride; iron / ethanol; water / 40 °C / Reflux
2.1: triethylamine / dichloromethane / 0 - 20 °C
3.1: acetic anhydride; potassium acetate; acetic acid / chloroform / 0.25 h / 20 °C
3.2: 40 - 60 °C
3.3: 0 - 20 °C
View Scheme
Multi-step reaction with 3 steps
1: hydrogenchloride; iron / water; industrial methylated spirit / 2 h / Reflux
2: triethylamine / dichloromethane / 90 h / 20 °C
3: acetic anhydride; potassium acetate; isopentyl nitrite / chloroform; acetic acid / 20 - 60 °C
View Scheme
Multi-step reaction with 4 steps
1.1: acetic acid; iron / 2 h / Reflux
2.1: triethylamine / dichloromethane / 18 h
2.2: 1 h
3.1: acetic anhydride; potassium acetate; acetic acid; isopentyl nitrite / toluene / 3 h / Reflux
4.1: potassium carbonate; methanol / 1 h / Reflux
View Scheme
5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

N-(5-bromo-2-methyl-pyridin-3-yl)-acetamide
1301214-71-0

N-(5-bromo-2-methyl-pyridin-3-yl)-acetamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: hydrogenchloride; iron / ethanol; water / 40 °C / Reflux
2: triethylamine / dichloromethane / 0 - 20 °C
View Scheme
Multi-step reaction with 2 steps
1: hydrogenchloride; iron / water; industrial methylated spirit / 2 h / Reflux
2: triethylamine / dichloromethane / 90 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1.1: acetic acid; iron / 2 h / Reflux
2.1: triethylamine / dichloromethane / 18 h
2.2: 1 h
View Scheme
5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

1H-pyrazolo[4,3-b]pyridine-6-carboxylic acid methyl ester
1301214-72-1

1H-pyrazolo[4,3-b]pyridine-6-carboxylic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: hydrogenchloride; iron / ethanol; water / 40 °C / Reflux
2.1: triethylamine / dichloromethane / 0 - 20 °C
3.1: acetic anhydride; potassium acetate; acetic acid / chloroform / 0.25 h / 20 °C
3.2: 40 - 60 °C
3.3: 0 - 20 °C
4.1: triethylamine / 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; palladium dichloride / acetonitrile / 18 h / 100 °C / 15001.5 Torr
View Scheme
Multi-step reaction with 4 steps
1: hydrogenchloride; iron / water; industrial methylated spirit / 2 h / Reflux
2: triethylamine / dichloromethane / 90 h / 20 °C
3: acetic anhydride; potassium acetate; isopentyl nitrite / chloroform; acetic acid / 20 - 60 °C
4: triethylamine / (S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine); palladium dichloride / acetonitrile / 18 h / 100 °C / 15001.5 Torr
View Scheme
Multi-step reaction with 4 steps
1: iron; ammonium chloride / water; ethanol / 0.17 h / 90 °C
2: acetic acid / 20 °C
3: acetic anhydride; isopentyl nitrite; potassium acetate / toluene / 90 °C / Inert atmosphere
4: triethylamine; bis-triphenylphosphine-palladium(II) chloride / 100 °C / 7600.51 Torr
View Scheme
5-bromo-2-methyl-3-nitropyridine
911434-05-4

5-bromo-2-methyl-3-nitropyridine

1H-pyrazolo[4,3-b] pyridine-6-carboxylic acid
1256807-59-6

1H-pyrazolo[4,3-b] pyridine-6-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: hydrogenchloride; iron / ethanol; water / 40 °C / Reflux
2.1: triethylamine / dichloromethane / 0 - 20 °C
3.1: acetic anhydride; potassium acetate; acetic acid / chloroform / 0.25 h / 20 °C
3.2: 40 - 60 °C
3.3: 0 - 20 °C
4.1: triethylamine / 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; palladium dichloride / acetonitrile / 18 h / 100 °C / 15001.5 Torr
5.1: sodium hydroxide; water / methanol / 0 - 20 °C
5.2: pH 5 - 6
View Scheme
Multi-step reaction with 5 steps
1.1: hydrogenchloride; iron / water; industrial methylated spirit / 2 h / Reflux
2.1: triethylamine / dichloromethane / 90 h / 20 °C
3.1: acetic anhydride; potassium acetate; isopentyl nitrite / chloroform; acetic acid / 20 - 60 °C
4.1: triethylamine / (S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine); palladium dichloride / acetonitrile / 18 h / 100 °C / 15001.5 Torr
5.1: sodium hydroxide; water / methanol / 18 h / 20 °C
5.2: pH 5 - 6
View Scheme
Multi-step reaction with 5 steps
1: iron; ammonium chloride / water; ethanol / 0.17 h / 90 °C
2: acetic acid / 20 °C
3: acetic anhydride; isopentyl nitrite; potassium acetate / toluene / 90 °C / Inert atmosphere
4: triethylamine; bis-triphenylphosphine-palladium(II) chloride / 100 °C / 7600.51 Torr
5: water; sodium hydroxide / 20 °C
View Scheme

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