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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis

Ipragliflozin L-proline

Cas:951382-34-6

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 951382-34-6 with competitive price

Cas:951382-34-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best serv

99%min Lglinide Valine 951382-34-6

Cas:951382-34-6

Min.Order:10 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Qingdao Beluga Import and Export Co., LTD

L-Proline compd. with (1S)-1,5-anhydro-1-C-[3-(benzo[b]thien-2-ylmethyl)-4-fluorophenyl]-D-glucitol (1:1) CAS:951382-34-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, pro

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Triumph International Development Limilted

Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By

Ipragliflozin L-proline

Cas:951382-34-6

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

IPRAGLIFLOZIN L-PROLINE

Cas:951382-34-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Siwei Development Group Ltd.

Product name: Ipragliflozin L-Proline CAS No.:951382-34-6 Molecule Formula:C26H30FNO7S Molecule Weight:519.58 Purity: 99% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard TESTING ITEMS

High Quality Ipragliflozin L-Proline in stock

Cas:951382-34-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

L-Proline compd. with (1S)-1,5-anhydro-1-C-[3-(benzo[b]thien-2-ylmethyl)-4-fluorophenyl]-D-glucitol (1:1)

Cas:951382-34-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

L-Proline compd. with (1S)-1,5-anhydro-1-C-[3-(benzo[b]thien-2-ylmethyl)-4-fluorophenyl]-D-glucitol (1:1)

Cas:951382-34-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service an

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

Ipragliflozin L-Proline

Cas:951382-34-6

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Hangzhou Dingyan Chem Co., Ltd

high purity, manufacturer Application:Intermediate

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

Shanghai SE Pharm Co., Ltd

made in GMP Package:1kg, 10kgs, 100kgs Application:Anti-diabetic drugs Transportation:sea OR air Port:any China Port

Ipragliflozin L-proline

Cas:951382-34-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Chemical intermediate

Guangdong Juda Chemical Industrial Co.,Limited

Factory supply high purity low priceAppearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

Ipragliflozin L-proline CAS No.951382-34-6

Cas:951382-34-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

951382-34-6

Cas:951382-34-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Asure Biochem CO.,LTD.

*stable and better quality products*efficient and meticulous servicesAppearance:Powder Storage:Store in dry, cool and ventilated place Package:1kg/tin 5kg/tin 25kg/carton Application:Pharmaceutical raw materials, making injection powder oral agent Tr

Ipragliflozin L-proline

Cas:951382-34-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Synthetic route

(2S,3R,4R,5S,6R)-2-(3-(benzo[b]thiophen-2-ylmethyl)-4-fluorophenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
761423-87-4

(2S,3R,4R,5S,6R)-2-(3-(benzo[b]thiophen-2-ylmethyl)-4-fluorophenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

L-proline
147-85-3

L-proline

Ipragliflozin L-proline
951382-34-6

Ipragliflozin L-proline

Conditions
ConditionsYield
In dichloromethane at 35℃; for 3h;99%
In ethanol; water at 100℃; for 0.5h;83.7%
In ethanol at 100℃; for 0.5h;
2,3,4,6-tetra-O-pivaloyl-α-D-glucopyranosyl bromide
81058-27-7

2,3,4,6-tetra-O-pivaloyl-α-D-glucopyranosyl bromide

Ipragliflozin L-proline
951382-34-6

Ipragliflozin L-proline

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: n-butyllithium / toluene; dibutyl ether / 3 h / -20 °C
1.2: 1 h / 0 °C
1.3: 3 h / 100 °C
2.1: sodium methylate; methanol / 3 h / 65 °C
3.1: ethanol; water / 0.5 h / 100 °C
View Scheme
Multi-step reaction with 3 steps
1.1: n-butyllithium / toluene; hexane; dibutyl ether / 3.33 h / -20 °C / Inert atmosphere
1.2: 1.33 h / 0 °C / Inert atmosphere
1.3: 3 h / 100 °C / Inert atmosphere
2.1: sodium methylate; methanol / 3 h / 65 °C
3.1: ethanol; water / 0.5 h / 100 °C
View Scheme
(2R,3R,4S,5R,6R)-2-chloro-6-(pivaloyloxymethyl)tetrahydro-2H-pyran-3,4,5-triyl tris(2,2-dimethylpropanoate)

(2R,3R,4S,5R,6R)-2-chloro-6-(pivaloyloxymethyl)tetrahydro-2H-pyran-3,4,5-triyl tris(2,2-dimethylpropanoate)

Ipragliflozin L-proline
951382-34-6

Ipragliflozin L-proline

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: n-butyllithium / toluene; dibutyl ether / 3 h / -20 °C
1.2: 1 h / 0 °C
1.3: 3 h / 100 °C
2.1: sodium methylate; methanol / 3 h / 65 °C
3.1: ethanol; water / 0.5 h / 100 °C
View Scheme
2-[(5-iodo-2-fluorophenyl)methyl]-1-benzothiophene

2-[(5-iodo-2-fluorophenyl)methyl]-1-benzothiophene

Ipragliflozin L-proline
951382-34-6

Ipragliflozin L-proline

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: n-butyllithium / toluene; dibutyl ether / 3 h / -20 °C
1.2: 1 h / 0 °C
1.3: 3 h / 100 °C
2.1: sodium methylate; methanol / 3 h / 65 °C
3.1: ethanol; water / 0.5 h / 100 °C
View Scheme
Multi-step reaction with 3 steps
1.1: n-butyllithium / toluene; hexane; dibutyl ether / 3.33 h / -20 °C / Inert atmosphere
1.2: 1.33 h / 0 °C / Inert atmosphere
1.3: 3 h / 100 °C / Inert atmosphere
2.1: sodium methylate; methanol / 3 h / 65 °C
3.1: ethanol; water / 0.5 h / 100 °C
View Scheme
2-[(5-bromo-2-fluorophenyl)methyl]-1-benzothiophene
1034305-17-3

2-[(5-bromo-2-fluorophenyl)methyl]-1-benzothiophene

Ipragliflozin L-proline
951382-34-6

Ipragliflozin L-proline

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: n-butyllithium / toluene; dibutyl ether / 3 h / -20 °C
1.2: 1 h / 0 °C
1.3: 3 h / 100 °C
2.1: sodium methylate; methanol / 3 h / 65 °C
3.1: ethanol; water / 0.5 h / 100 °C
View Scheme
Multi-step reaction with 3 steps
1.1: n-butyllithium / dibutyl ether; toluene; n-heptane / 2 h / -40 °C / Inert atmosphere
1.2: 2 h / 20 - 90 °C
2.1: pentamethylbenzene,; boron trichloride / dichloromethane / 4 h / -78 °C
3.1: dichloromethane / 3 h / 35 °C
View Scheme
(1S)-1,5-anhydro-1-{3-[(1-benzothiophen-2-yl)methyl]-4-fluorophenyl}-2,3,4,6-tetra-O-pivaloyl-D-glucitol

(1S)-1,5-anhydro-1-{3-[(1-benzothiophen-2-yl)methyl]-4-fluorophenyl}-2,3,4,6-tetra-O-pivaloyl-D-glucitol

Ipragliflozin L-proline
951382-34-6

Ipragliflozin L-proline

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium methylate; methanol / 3 h / 65 °C
2: ethanol; water / 0.5 h / 100 °C
View Scheme
α-D-glucopyranose peracetylate
604-68-2

α-D-glucopyranose peracetylate

Ipragliflozin L-proline
951382-34-6

Ipragliflozin L-proline

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: hydrogen bromide; acetic acid / dichloromethane / 0.67 h / 0 °C
2.1: Acidic conditions
3.1: iron(II) sulfate / methanol / 12 h
4.1: n-butyllithium / dibutyl ether; toluene; n-heptane / 2 h / -40 °C / Inert atmosphere
4.2: 2 h / 20 - 90 °C
5.1: pentamethylbenzene,; boron trichloride / dichloromethane / 4 h / -78 °C
6.1: dichloromethane / 3 h / 35 °C
View Scheme
2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide
572-09-8

2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide

Ipragliflozin L-proline
951382-34-6

Ipragliflozin L-proline

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: Acidic conditions
2.1: iron(II) sulfate / methanol / 12 h
3.1: n-butyllithium / dibutyl ether; toluene; n-heptane / 2 h / -40 °C / Inert atmosphere
3.2: 2 h / 20 - 90 °C
4.1: pentamethylbenzene,; boron trichloride / dichloromethane / 4 h / -78 °C
5.1: dichloromethane / 3 h / 35 °C
View Scheme
Benzo[b]thiophene
95-15-8

Benzo[b]thiophene

Ipragliflozin L-proline
951382-34-6

Ipragliflozin L-proline

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: n-butyllithium / tetrahydrofuran / 1.5 h / -78 °C
1.2: 2 h / -78 °C
2.1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane / 0.5 h / -20 °C
3.1: n-butyllithium / dibutyl ether; toluene; n-heptane / 2 h / -40 °C / Inert atmosphere
3.2: 2 h / 20 - 90 °C
4.1: pentamethylbenzene,; boron trichloride / dichloromethane / 4 h / -78 °C
5.1: dichloromethane / 3 h / 35 °C
View Scheme
5-bromo-2-fluorobenzaldehyde
93777-26-5

5-bromo-2-fluorobenzaldehyde

Ipragliflozin L-proline
951382-34-6

Ipragliflozin L-proline

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: n-butyllithium / tetrahydrofuran / 1.5 h / -78 °C
1.2: 2 h / -78 °C
2.1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane / 0.5 h / -20 °C
3.1: n-butyllithium / dibutyl ether; toluene; n-heptane / 2 h / -40 °C / Inert atmosphere
3.2: 2 h / 20 - 90 °C
4.1: pentamethylbenzene,; boron trichloride / dichloromethane / 4 h / -78 °C
5.1: dichloromethane / 3 h / 35 °C
View Scheme
1-bromo-α-D-glucopyranose
61403-85-8

1-bromo-α-D-glucopyranose

Ipragliflozin L-proline
951382-34-6

Ipragliflozin L-proline

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: iron(II) sulfate / methanol / 12 h
2.1: n-butyllithium / dibutyl ether; toluene; n-heptane / 2 h / -40 °C / Inert atmosphere
2.2: 2 h / 20 - 90 °C
3.1: pentamethylbenzene,; boron trichloride / dichloromethane / 4 h / -78 °C
4.1: dichloromethane / 3 h / 35 °C
View Scheme
2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl bromide
4196-35-4

2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl bromide

Ipragliflozin L-proline
951382-34-6

Ipragliflozin L-proline

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: n-butyllithium / dibutyl ether; toluene; n-heptane / 2 h / -40 °C / Inert atmosphere
1.2: 2 h / 20 - 90 °C
2.1: pentamethylbenzene,; boron trichloride / dichloromethane / 4 h / -78 °C
3.1: dichloromethane / 3 h / 35 °C
View Scheme
(1-benzothiophen-2-yl)(5-bromo-2-fluorophenyl)methanol
1034305-11-7

(1-benzothiophen-2-yl)(5-bromo-2-fluorophenyl)methanol

Ipragliflozin L-proline
951382-34-6

Ipragliflozin L-proline

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane / 0.5 h / -20 °C
2.1: n-butyllithium / dibutyl ether; toluene; n-heptane / 2 h / -40 °C / Inert atmosphere
2.2: 2 h / 20 - 90 °C
3.1: pentamethylbenzene,; boron trichloride / dichloromethane / 4 h / -78 °C
4.1: dichloromethane / 3 h / 35 °C
View Scheme
alpha-D-glucopyranose
492-62-6

alpha-D-glucopyranose

Ipragliflozin L-proline
951382-34-6

Ipragliflozin L-proline

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: sodium acetate / 0.17 h / 140 °C
2.1: hydrogen bromide; acetic acid / dichloromethane / 0.67 h / 0 °C
3.1: Acidic conditions
4.1: iron(II) sulfate / methanol / 12 h
5.1: n-butyllithium / dibutyl ether; toluene; n-heptane / 2 h / -40 °C / Inert atmosphere
5.2: 2 h / 20 - 90 °C
6.1: pentamethylbenzene,; boron trichloride / dichloromethane / 4 h / -78 °C
7.1: dichloromethane / 3 h / 35 °C
View Scheme

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