1010396-60-7Relevant articles and documents
Formal [3+2] annulation involving allylic bromides and thioureas. synthesis of 2-iminothiazolidines through a base-catalyzed intramolecular anti-Michael addition
Ferreira, Misael,Sá, Marcus M.
, p. 829 - 833 (2015)
A simple and efficient protocol was developed for the synthesis of 2-iminothiazolidines through a base-mediated [3+2] annulation involving substituted thioureas and allylic bromides bearing electron-withdrawing groups. This domino process consists of nucleophilic displacement, followed by intramolecular anti-Michael addition of the preformed allylic isothiourea under mild conditions to give the thiazolidine core.
Design, synthesis and evaluation of 3-arylidene azetidin-2-ones as potential antifungal agents against Alternaria solani Sorauer
Delong, Wang,Yongling, Wu,Lanying, Wang,Juntao, Feng,Xing, Zhang
, p. 6661 - 6673 (2017/11/17)
A new concise and facile method was explored to synthesize a collection of new 3-arylidene azetidin-2-ones, which could be regarded as the derivatives of the hybrid scaffold of bioactive natural cinnamamide and heterocycle azetidi-2-one. The structures of
A phenacrylate scaffold for tunable thiol activation and release
Sankar, Rathinam K.,Kumbhare, Rohan S.,Dharmaraja, Allimuthu T.,Chakrapani, Harinath
supporting information, p. 15323 - 15326 (2015/01/09)
A thiol-selective 2-methyl-3-phenacrylate scaffold with spatiotemporal control over delivery of a cargo is reported. The half-lives of decomposition could be tuned from 30 min to 1 day and the scaffold's utility in thiol-inducible fluorophore release in cell-free as well as within cells is demonstrated.