886228-59-7

Basic information

• Product Name: 3-(4-fluoro-phenyl)-2-hydroxymethyl-acrylic acid methyl ester
• Synonyms: 3-(4-fluoro-phenyl)-2-hydroxymethyl-acrylic acid methyl ester
• CAS NO: 886228-59-7
• Molecular Weight: 210.205
• Mol File: 886228-59-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(4-fluoro-phenyl)-2-hydroxymethyl-acrylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-fluoro-phenyl)-2-hydroxymethyl-acrylic acid methyl ester(886228-59-7)
• EPA Substance Registry System: 3-(4-fluoro-phenyl)-2-hydroxymethyl-acrylic acid methyl ester(886228-59-7)

Safety Data

• Hazardous Substances Data: 886228-59-7(Hazardous Substances Data)

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 1010396-60-7 methyl (Z)-4-(bromomethyl)-3-(4-fluorophenyl)-2-propenoate 

Downstream Products

• 1010396-60-7 methyl (Z)-4-(bromomethyl)-3-(4-fluorophenyl)-2-propenoate 
• 886228-75-7 4-[2-(tert-butyl-dimethyl-silanyloxymethyl)-3-(4-fluoro-phenyl)-allyl]-morpholine 
• 886228-60-0 2-(tert-butyl-dimethyl-silanyloxymethyl)-3-(4-fluoro-phenyl)-prop-2-en-1-ol 
• 886228-73-5 2-(tert-butyl-dimethyl-silanyloxymethyl)-3-(4-fluoro-phenyl)-acrylic acid methyl ester 

Relevant articles and documents

Stereoselective synthesis of a potent human NK1 receptor antagonist via acyl-Claisen rearrangement

Stereoselective synthesis of the tetrahydropyran derivative 1 is reported. Diastereoselective acyl-Claisen rearrangement was employed for formation of C3 and C4 chiral centres on the tetrahydropyran ring. Georg Thieme Verlag Stuttgart.