1013330-69-2

Basic information

• Product Name: N-[[4-[[[4-[[tert-Butyloxycarbonyl]aMino][1,1'-biphenyl]-3-yl]aMino]carbonyl]phenyl]Methyl]carbaMic Acid Methyl Ester
• Synonyms: N-[[4-[[[4-[[tert-Butyloxycarbonyl]aMino][1,1'-biphenyl]-3-yl]aMino]carbonyl]phenyl]Methyl]carbaMic Acid Methyl Ester;N-[[4-[[[4-[[(1,1-Dimethylethoxy)carbonyl]amino][1,1'-biphenyl]-3-yl]amino]carbonyl]phenyl]methyl]carbamic acid methyl ester
• CAS NO: 1013330-69-2
• Molecular Formula: C₂₇H₂₉N₃O₅
• Molecular Weight: 475.53626
• Product Categories: Amines, Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 1013330-69-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator
• Solubility: Dimethylsulfoxide, Methanol
• CAS DataBase Reference: N-[[4-[[[4-[[tert-Butyloxycarbonyl]aMino][1,1'-biphenyl]-3-yl]aMino]carbonyl]phenyl]Methyl]carbaMic Acid Methyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-[[4-[[[4-[[tert-Butyloxycarbonyl]aMino][1,1'-biphenyl]-3-yl]aMino]carbonyl]phenyl]Methyl]carbaMic Acid Methyl Ester(1013330-69-2)
• EPA Substance Registry System: N-[[4-[[[4-[[tert-Butyloxycarbonyl]aMino][1,1'-biphenyl]-3-yl]aMino]carbonyl]phenyl]Methyl]carbaMic Acid Methyl Ester(1013330-69-2)

Safety Data

• Hazardous Substances Data: 1013330-69-2(Hazardous Substances Data)

Usage

Description

N-[[4-[[[4-[[tert-Butyloxycarbonyl]amino][1,1'-biphenyl]-3-yl]amino]carbonyl]phenyl]methyl]carbamic Acid Methyl Ester is a complex organic compound that serves as a reactant in the development of biaryl selective histone deacetylase (HDAC) inhibitors. Its unique structure allows for the optimization of these inhibitors, which are crucial in the study and treatment of various diseases.

Uses

Used in Pharmaceutical Industry:
N-[[4-[[[4-[[tert-Butyloxycarbonyl]amino][1,1'-biphenyl]-3-yl]amino]carbonyl]phenyl]methyl]carbamic Acid Methyl Ester is used as a reactant for the optimization of biaryl selective HDAC1&2 inhibitors. This application is significant because HDAC inhibitors have potential therapeutic benefits in the treatment of various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. By optimizing these inhibitors, researchers can develop more effective and targeted treatments with fewer side effects.

Upstream product

• 1003316-11-7 1,1-dimethylethyl {3-[({4-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}carbonyl) amino]biphenyl-4-yl}carbamate 
• 1003316-10-6 tert-butyl 3-(4-(chloromethyl)benzamido)biphenyl-4-ylcarbamate 
• 335255-33-9 tert-butyl (3-amino-4-biphenylyl)carbamate 
• 876-08-4 p-(chloromethyl)benzoyl chloride 
• 1003316-12-8 tert-butyl (3-(4-(aminomethyl)benzamido)-[1,1'-biphenyl]-4-yl)carbamate 
• 79-22-1 methyl chloroformate 

Downstream Products

• 1013330-79-4 methyl [(4-{[(4-aminobiphenyl-3-yl)amino]carbonyl}phenyl)methyl]carbamate 

Relevant articles and documents

4-CARBOXYBENZYLAMINO DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS

The present invention relates to a novel class of 4-carboxybenzylamino derivatives. The 4-carboxybenzylamino compounds can be used to treat cancer. The 4-carboxybenzylamino compounds can also inhibit histone deacetylase and are suitable for use in selecti