103203-54-9

Basic information

• Product Name: 4-(2-METHOXYPHENOXY)BENZOIC ACID
• Synonyms: 4-(2-METHOXYPHENOXY)BENZOIC ACID;2-(4-Carboxyphenoxy)anisole
• CAS NO: 103203-54-9
• Molecular Formula: C₁₄H₁₂O₄
• Molecular Weight: 244.24
• Mol File: 103203-54-9.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(2-METHOXYPHENOXY)BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-METHOXYPHENOXY)BENZOIC ACID(103203-54-9)
• EPA Substance Registry System: 4-(2-METHOXYPHENOXY)BENZOIC ACID(103203-54-9)

Safety Data

• Hazard Codes: Xn,N
• Statements: 22-43-50
• Safety Statements: 36/37-61
• Hazardous Substances Data: 103203-54-9(Hazardous Substances Data)

Usage

Description

4-(2-Methoxyphenoxy)benzoic acid, with the molecular formula C14H12O4 and CAS number 1816-71-7, is a white solid chemical compound that is insoluble in water but soluble in organic solvents. It is commonly used in the synthesis of pharmaceuticals and as a building block for organic compounds. Due to its unique chemical structure, this compound has potential applications in the development of new drugs, agrochemicals, and materials, making it a versatile compound with a wide range of potential uses and research applications in various scientific fields.

Uses

Used in Pharmaceutical Industry:
4-(2-Methoxyphenoxy)benzoic acid is used as a building block for the synthesis of various pharmaceuticals, contributing to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
4-(2-METHOXYPHENOXY)BENZOIC ACID is used as a starting material for the synthesis of agrochemicals, which can be employed in the development of new pesticides, herbicides, and other agricultural products to improve crop yield and protect plants from pests.
Used in Materials Science:
4-(2-Methoxyphenoxy)benzoic acid is used as a component in the development of new materials, such as polymers and composites, due to its unique chemical structure and properties. This can lead to the creation of innovative materials with improved performance characteristics for various applications.
Used in Research Applications:
4-(2-METHOXYPHENOXY)BENZOIC ACID serves as a valuable research tool in various scientific fields, including chemistry, biology, and materials science, for studying its properties, interactions, and potential applications in the development of new products and technologies.

Upstream product

• 3402-84-4 1-methoxy-2-(4-methylphenoxy)benzene 
• 101093-91-8 methyl 4-(2-methoxyphenoxy)benzoate 
• 120-47-8 Ethyl 4-hydroxybenzoate 
• 578-57-4 2-bromoanisole 
• 110-86-1 pyridine 
• 2552-45-6 methyl 4-chloro-3,5-dinitrobenzoate 
• 107922-35-0 3,5-diiodo-4-(2-methoxy-phenoxy)-benzoic acid methyl ester 
• 108621-37-0 4-(2-methoxy-phenoxy)-3,5-dinitro-benzoic acid methyl ester 
• 90-05-1 2-methoxy-phenol 
• 106-38-7 para-bromotoluene 
• 5633-98-7 potassium guaiacolate 
• 78725-48-1 4-(2-methoxyphenoxy)benzaldehyde 
• 459-57-4 4-fluorobenzaldehyde 
• 1194-02-1 4-fluorobenzonitrile 

Downstream Products

• 913829-13-7 (4-ethyl-5-{5-[4-(2-methoxyphenoxy)phenyl]-1,2,4-oxadiazol-3-yl}-2-thienyl)methanol 
• 1436378-51-6 N-(1S)-1-{[(3S)-4-(3-hydroxyphenyl)-3-methylpiperazin-1-yl]-methyl}-2-methylpropyl-4-(2-methoxyphenoxy)benzamide 
• 1436378-52-7 N-(1S)-1-{[(3S)-4-(3-hydroxyphenyl)-3-methylpiperazin-1-yl]-methyl}-2-methylpropyl-4-(2-hydroxyphenoxy)benzamide 
• 1446443-97-5 N-[(dimethylamino)sulfonyl]-4-(2-methoxyphenoxy)benzamide diethylamine salt 
• 1377995-67-9 C₂₃H₃₀N₂O₃ 

Relevant articles and documents

Beyond Basicity: Discovery of Nonbasic DENV-2 Protease Inhibitors with Potent Activity in Cell Culture

The viral serine protease NS2B-NS3 is one of the promising targets for drug discovery against dengue virus and other flaviviruses. The molecular recognition preferences of the protease favor basic, positively charged moieties as substrates and inhibitors, which leads to pharmacokinetic liabilities and off-target interactions with host proteases such as thrombin. We here present the results of efforts that were aimed specifically at the discovery and development of noncharged, small-molecular inhibitors of the flaviviral proteases. A key factor in the discovery of these compounds was a cellular reporter gene assay for the dengue protease, the DENV2proHeLa system. Extensive structure-activity relationship explorations resulted in novel benzamide derivatives with submicromolar activities in viral replication assays (EC50 0.24 μM), selectivity against off-target proteases, and negligible cytotoxicity. This structural class has increased drug-likeness compared to most of the previously published active-site-directed flaviviral protease inhibitors and includes promising candidates for further preclinical development.

N-AMINOSULFONYL BENZAMIDES

The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulphonamide Nav 1.7 inhibitors of formula (I) or a pharmaceutically acceptable salt thereof, wherein Z, R1a, R1b, R2, R3, R4 and R5 are as defined in the description. Nay 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain

1-SUBSTITUTED 4-ARYLPIPERAZINE AS KAPPA OPIOID RECEPTOR ANTAGONISTS

Provided are compounds represented by the formula: where R, Y3, R1,R2, R3, R4, R6, G, R7, E1, E2, A, B, W, X, Y and Z are as defined herein.