1043906-08-6 Usage
Description
1-(5-bromopyridin-2-yl)-1H-benzimidazole is a heterocyclic organic compound characterized by its molecular formula C13H8BrN3. It features a benzimidazole core with a 5-bromopyridin-2-yl moiety attached to the 1-position, which endows the molecule with unique chemical properties. 1-(5-bromopyridin-2-yl)-1H-benzimidazole holds potential for various applications in pharmaceutical research and drug development, making it a promising candidate for further exploration in the field of medicinal chemistry.
Uses
Used in Pharmaceutical Research:
1-(5-bromopyridin-2-yl)-1H-benzimidazole is used as a chemical compound in pharmaceutical research for its potential to be developed into a drug candidate. The presence of bromine and pyridine groups in its structure provides unique chemical properties that can be exploited for specific purposes in medicinal chemistry.
Used in Drug Development:
In the field of drug development, 1-(5-bromopyridin-2-yl)-1H-benzimidazole is utilized as a building block for the synthesis of novel bioactive compounds. Its heterocyclic structure and the distinctive chemical properties of the bromine and pyridine groups make it a valuable component in the creation of new pharmaceutical agents.
Used in Medicinal Chemistry:
1-(5-bromopyridin-2-yl)-1H-benzimidazole is employed as a key component in medicinal chemistry, where its unique structure and properties can be leveraged to design and develop new drugs with specific therapeutic targets and applications.
Used in Chemical Synthesis:
1-(5-bromopyridin-2-yl)-1H-benzimidazole is also used as an intermediate in chemical synthesis, particularly for the creation of other heterocyclic compounds with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 1043906-08-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,3,9,0 and 6 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1043906-08:
(9*1)+(8*0)+(7*4)+(6*3)+(5*9)+(4*0)+(3*6)+(2*0)+(1*8)=126
126 % 10 = 6
So 1043906-08-6 is a valid CAS Registry Number.
1043906-08-6Relevant articles and documents
Copper-Catalyzed C-N Bond Exchange of N-Heterocyclic Substituents around Pyridine and Pyrimidine Cores
Tao, Sheng,Ji, Enhui,Shi, Lei,Liu, Ning,Xu, Liang,Dai, Bin
, p. 5120 - 5130 (2017)
A copper-catalyzed transfer N-heteroarylation strategy using a C-N bond exchange reaction is described. This reaction accommodates a wide range of pyridine and pyrimidine rings bearing halogen atoms, which have wide utility for subsequent transformations. This method provides a direct and operationally simple approach for modifying complex molecules by the exchange of N-heterocyclic substituents.
Sequential metal-catalyzed N-heteroarylation and C-C cross-coupling reactions: An expedient route to tris(hetero)aryl systems
Siddle, Jamie S.,Batsanov, Andrei S.,Bryce, Martin R.
experimental part, p. 2746 - 2750 (2009/04/07)
This paper describes copper-catalyzed N-C heteroarylation of benzimidazole, 1-methylbenzimidazolone, imidazole and pyrrole. The products of these reactions then undergo palladium-catalyzed C-C cross-couplings with aryl or heteroarylboronic acids under Suzuki-Miyaura conditions to provide a rapid entry, from readily-available reagents, into tris(hetero)-aryl scaffolds comprising two or three N-heterocyclic rings. The sequential N-C and C-C couplings can be performed in a one-pot process (two examples are given: >50% overall yields). Wiley-VCH Verlag GmbH & Co. KGaA, 2008.
