105851-89-6

Basic information

• Product Name: 2,2-Dimethyl-propionic acid (S)-1-[(S)-1-((1S,2S,4S)-4-butylcarbamoyl-1-cyclohexylmethyl-2-hydroxy-5-methyl-hexylcarbamoyl)-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl ester
• Synonyms: 2,2-Dimethyl-propionic acid (S)-1-[(S)-1-((1S,2S,4S)-4-butylcarbamoyl-1-cyclohexylmethyl-2-hydroxy-5-methyl-hexylcarbamoyl)-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl ester
• CAS NO: 105851-89-6
• Molecular Weight: 695.943
• Mol File: 105851-89-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,2-Dimethyl-propionic acid (S)-1-[(S)-1-((1S,2S,4S)-4-butylcarbamoyl-1-cyclohexylmethyl-2-hydroxy-5-methyl-hexylcarbamoyl)-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-Dimethyl-propionic acid (S)-1-[(S)-1-((1S,2S,4S)-4-butylcarbamoyl-1-cyclohexylmethyl-2-hydroxy-5-methyl-hexylcarbamoyl)-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl ester(105851-89-6)
• EPA Substance Registry System: 2,2-Dimethyl-propionic acid (S)-1-[(S)-1-((1S,2S,4S)-4-butylcarbamoyl-1-cyclohexylmethyl-2-hydroxy-5-methyl-hexylcarbamoyl)-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl ester(105851-89-6)

Safety Data

• Hazardous Substances Data: 105851-89-6(Hazardous Substances Data)

Upstream product

• 14997-58-1 N-[(benzyloxy)carbonyl]-L-histidine 
• 74853-62-6 N^α,N^im-ditritylhistidine 
• 105852-42-4 2-<<3-(benzyloxycarbonyl)-4-(cyclohexylmethyl)-2,2-dimethyl-(4S)-1,3-oxazolidin-5-yl>methyl>-3-methyl-(2S)-butyric acid 
• 114469-37-3 ((1S,2R)-1-Cyclohexylmethyl-2-hydroxy-3-iodo-propyl)-carbamic acid benzyl ester 
• 105852-63-9 [(S)-1-((1S,2S,4S)-4-Butylcarbamoyl-1-cyclohexylmethyl-2-hydroxy-5-methyl-hexylcarbamoyl)-2-(1H-imidazol-4-yl)-ethyl]-carbamic acid benzyl ester 
• 114469-35-1 3-<(benzyloxycarbonyl)amino>-4-cyclohexyl-1-iodo-2-<(trimethylsilyl)oxy>-(2R,3S)-butane 
• 105852-84-4 benzyl O-pivaloyl-L-phenyllactate 
• 105852-65-1 (2S)-2-[(4S,5S)-3-benzyloxycarbonyl-4-cyclohexylmethyl-2,2-dimethyl-1,3-oxazolidin-5-yl]methyl-N-butyl-3-methylbutanamide 
• 105852-64-0 (2S,4S,5S)-5-amino-6-cyclohexyl-4-hydroxy-2-isopropyl hexanoic acid n-butyl amide 
• 105852-50-4 3-(benzyloxycarbonyl)-4-(cyclohexylmethyl)-2,2-dimethyl-5-(iodomethyl)-(4S,5R)-1,3-oxazolidine 
• 3282-30-2 pivaloyl chloride 
• 7622-21-1 benzyl-(S)-(-)-2-hydroxy-3-phenylpropionate 
• 20312-36-1 L-3-phenyllactic acid 
• 556-24-1 methyl 3-methylbutanoate 

Relevant articles and documents

Synthesis and biological activity of some transition-state inhibitors of human renin

A series of renin inhibitors containing the dipeptide transition state mimics (2S,4S,5S)-5-amino-4-hydroxy-2-isopropyl-7-methyloctanoic acid (Leu-(OH)-Val) and (2S,4S,5S)-5-amino-4-hydroxy-2-isopropyl-6-cyclohexylhexanoic acid (Cha-(OH)-Val) was prepared.