106877-42-3

Basic information

• Product Name: Benzene, 2,4-dimethoxy-1-(trifluoromethyl)-
• Synonyms: 2,4-dimethoxy-(trifluoromethyl)benzene;2,4-Dimethoxy-1-trifluoromethyl-benzene;1,3-dimethoxy-4-trifluoromethylbenzene;2,4-dimethoxy-1-(trifluoromethyl)benzene
• CAS NO: 106877-42-3
• Molecular Formula: C9H9F3O2
• Molecular Weight: 206.164
• Mol File: 106877-42-3.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: Benzene, 2,4-dimethoxy-1-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 2,4-dimethoxy-1-(trifluoromethyl)-(106877-42-3)
• EPA Substance Registry System: Benzene, 2,4-dimethoxy-1-(trifluoromethyl)-(106877-42-3)

Safety Data

• Hazardous Substances Data: 106877-42-3(Hazardous Substances Data)

Upstream product

• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 151-10-0 1,3-Dimethoxybenzene 
• 421-83-0 trifluoromethane sulfonyl chloride 
• 2926-29-6 Langlois reagent 
• 133730-34-4 2,4-dimethoxyphenylboronic acid 
• 149-73-5 trimethyl orthoformate 
• 75-63-8 Bromotrifluoromethane 
• 1214756-50-9 2-cyclopropyl-1-(trifluoromethyl)benzo[b]thiophenium triflate 
• 77152-08-0 trifluoromethylcopper(I) 
• 2735-04-8 2,4-Dimethoxyaniline 
• 1622092-08-3 2,4-dimethyl-7-(pentafluorosulfanyl)-5-(trifluoromethyl)dibenzo[b,d]thiophenium trifluoromethanesulfonate 
• 20469-63-0 1-iodo-2,4-dimethoxybenzene 
• 41804-89-1 potassium triflinate 

Relevant articles and documents

Copper-catalyzed trifluoromethylation of aryl- and vinylboronic acids with generation of CF3-radicals

The selective trifluoromethylation of aryl- and vinylboronic acids proceeds smoothly with CF3SO2Na (Langlois reagent) in the presence of copper catalysts and t-BuOOH. Therefore, the method relies both on transition metal catalysis an

The 2,4-dimethyl-7-pentafluorosulfanyl-5-(trifluoromethyl)dibenzo[b,d] thiophenium trifluoromethanesulfonate: The SF5-analog of Umemoto salt

The SF5-analog of the Umemoto salt was synthesized in just two steps by combining our recently reported SF5-biaryl synthesis, via Suzuki coupling with 4-(pentafluorosulfanyl)benzenediazonium tetrafluoroborate, with Magnier's one-pot synthesis of dibenzothiophenium salts employing CF 3SO2Na and triflic anhydride. The trifluoromethylating power of this novel onium salt toward reactive arenes was tested in a survey study on small scale.

COMPOUNDS

A compound of formula (I), or a pharmaceutical salt thereof.

VINYLFLUOROALKANE SULFONATE COMPOUND AND METHOD OF PRODUCING THE SAME

PROBLEM TO BE SOLVED: To provide a technique of regioselectively introducing a fluoroalkyl group such as a trifluoromethyl group to an outer carbon of 1,3-diketone. SOLUTION: The present invention provides a method for producing a vinylfluoroalkane sulfon