41804-89-1

Basic information

• Product Name: POTASSIUM TRIFLUOROMETHANESULFONATE
• Synonyms: POTASSIUM TRIFLATE;POTASSIUM TRIFLUOROMETHANESULFONATE;POTASSIUM TRIFLUOROMETHANESULFONIC ACID;POTASSIUM TRIFLUOROMETHANESULPHONATE;TRIFLUOROMETHANESULFONIC ACID POTASSIUM SALT;TRIFLUOROMETHANESULFINIC ACID, POTASSIUM SALT;potassium trifluoromethanesulphinate;Trifluoromethane sulphinic acid potassium salt
• CAS NO: 41804-89-1
• Molecular Formula: CF₃O₂S*K
• Molecular Weight: 172.17
• EINECS: 255-556-9
• Mol File: 41804-89-1.mol
• Article Data: 14

Chemical Properties

• Melting Point: 236-241 °C
• Boiling Point: 222.8 °C at 760 mmHg
• Flash Point: 88.5 °C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 0.0369mmHg at 25°C
• Stability: Stable. Incompatible with astrong oxidizing agents. Protect from moisture. Hygroscopic.
• CAS DataBase Reference: POTASSIUM TRIFLUOROMETHANESULFONATE(CAS DataBase Reference)
• NIST Chemistry Reference: POTASSIUM TRIFLUOROMETHANESULFONATE(41804-89-1)
• EPA Substance Registry System: POTASSIUM TRIFLUOROMETHANESULFONATE(41804-89-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-38-37-36
• Safety Statements: 26-36
• WGK Germany: 3
• F: 3-10
• Hazardous Substances Data: 41804-89-1(Hazardous Substances Data)

Usage

Description

POTASSIUM TRIFLUOROMETHANESULFONATE, also known as potassium triflate, is an inorganic salt that exists as a white powder. It is a stable and versatile reagent in organic synthesis, characterized by its strong electrophilic properties and ability to act as a good leaving group.

Uses

Used in Pharmaceutical Industry:
POTASSIUM TRIFLUOROMETHANESULFONATE is used as a reagent for the preparation of trifluoromethanesulfonyl (Tf) compounds, which are essential in the synthesis of various pharmaceuticals. The trifluoromethylsulfonyl group is known for its stability and reactivity, making it a valuable component in the development of new drugs.
Used in Organic Synthesis:
In the field of organic chemistry, POTASSIUM TRIFLUOROMETHANESULFONATE is used as a catalyst to facilitate a wide range of reactions, such as esterification, amidation, and alkylation. Its strong electrophilic nature and ability to act as a good leaving group make it a preferred choice for these processes.
Used in Material Science:
POTASSIUM TRIFLUOROMETHANESULFONATE is also utilized in the development of novel materials, such as ionic liquids and polymers, due to its unique chemical properties. These materials have potential applications in various industries, including energy storage, separation processes, and environmental remediation.

InChI:InChI=1/CHF3O2S.K/c2-1(3,4)7(5)6;/h(H,5,6);/q;+1/p-1

Upstream product

• 41804-88-0 1,3-Diphenyl-3-trifluoromethanesulfonyl-propan-1-one 
• 4855-02-1 benzyl trifluoromethyl sulfone 
• 105-36-2 ethyl bromoacetate 
• 335-05-7 Trifluoromethanesulfonyl fluoride 
• 34642-42-7 trifluoromethanesulfinic acid 
• 421-83-0 trifluoromethane sulfonyl chloride 
• 2923-16-2 potassium trifluoroacetate 
• 75-46-7 trifluoromethan 

Downstream Products

• 4855-02-1 benzyl trifluoromethyl sulfone 
• 52208-95-4 (2-(trifluoromethylsulfonyl)ethyl)benzene 
• 52208-97-6 ((E)-3-Trifluoromethanesulfonyl-allyl)-benzene 
• 35896-48-1 1-phenyl-2-((trifluoromethyl)sulfonyl)ethan-1-one 
• 52208-93-2 1-(4-Bromo-phenyl)-2-trifluoromethanesulfonyl-ethanone 
• 14156-52-6 2-(trifluoromethanesulfonyl)benzene-1,4-diol 
• 52209-01-5 1,2-diphenyl-2-(trifluormethanesulfonyl)ethanone 
• 60595-15-5 (phenylthio)[(trifluoromethyl)sulfonyl]methane 
• 161042-58-6 4'-chloro-2-<(trifluoromethyl)sulfonyl>acetophenone 
• 150619-45-7 4'-methoxy-2-<(trifluoromethyl)sulfonyl>acetophenone 
• 942-39-2 1-fluoro-4-((trifluoromethyl)sulfinyl)benzene 
• 3360-65-4 1-(trifluoromethyl)-2,3,5,6-tetramethylbenzene 
• 84355-10-2 1,4-dimethoxy-2-(trifluoromethyl)benzene 
• 106877-42-3 1,3-dimethoxy-4-(trifluoromethyl)benzene 

Relevant articles and documents

METHOD FOR PREPARING OXYSULPHIDE AND FLUORINATED DERIVATIVES IN THE PRESENCE OF AN ORGANIC SOLVENT

The present invention concerns a method for preparing an oxysulphide and fluorinated derivative of formula (III) Ea-SO3R (III) that comprises bringing a compound of formula (II) Ea-SOOR (II)—Ea representing the fluorine atom or a group having 1 to 10 carbon atoms chosen from the fluoroalkyls, the perfluoroalkyls and the fluoroalkenyls; and—R representing hydrogen, a monovalent cation or an alkyl group; into contact, in the presence of a polar aprotic organic solvent, with an oxidising agent.

Recyclable Trifluoromethylation Reagents from Fluoroform

We present a strategy to rationally prepare CF3- transfer reagents at ambient temperature from HCF3. We demonstrate that a highly reactive CF3- adduct can be synthesized from alkali metal hydride, HCF3, and borazine Lewis acids in quantitative yield at room temperature. These nucleophilic reagents transfer CF3- to substrates without additional chemical activation, and after CF3 transfer, the free borazine is quantitatively regenerated. These features enable syntheses of popular nucleophilic, radical, and electrophilic trifluoromethylation reagents with complete recycling of the borazine Lewis acid.

METHOD FOR PREPARING A SULFONIMIDE COMPOUND AND SALTS THEREOF

The present invention relates to a method for preparing an aqueous sulfonimide compound of the formula (Rf1—SO2) (Rf2—SO2)NH, wherein Rf1et Rf2 are independently selected from the group comprising: a fluorine atom and groups having 1 to 10 carbon atoms selected from the perfluoroalkyl, fluoroalkyl, fluoroalkenyl and fluoroallyl groups, from a mixture M1 including (Rf1—SO2)(Rf2—SO2)NH, Rf1SO2H and/or Rf2SO2H, Rf1SO2NH2 and/or Rf2SO2NH2, characterized in that said method includes an oxidation step of said mixture M1 using an oxidizing agent in order to obtain a mixture M2 including (Rf1—SO2)(Rf2—SO2)NH, Rf1SO3H and/or Rf2SO3H, and Rf1SO2NH2 and/or Rf2SO2NH2.