1072195-82-4

Basic information

• Product Name: (S)-1-(2-hydroxyethyl)-4-methyl-N-[4-(methylsulfonyl)phenyl]-5-[2-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide
• CAS NO: 1072195-82-4
• Molecular Weight: 466.481
• Mol File: 1072195-82-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-1-(2-hydroxyethyl)-4-methyl-N-[4-(methylsulfonyl)phenyl]-5-[2-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-(2-hydroxyethyl)-4-methyl-N-[4-(methylsulfonyl)phenyl]-5-[2-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide(1072195-82-4)
• EPA Substance Registry System: (S)-1-(2-hydroxyethyl)-4-methyl-N-[4-(methylsulfonyl)phenyl]-5-[2-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide(1072195-82-4)

Safety Data

• Hazardous Substances Data: 1072195-82-4(Hazardous Substances Data)

Upstream product

• 880778-75-6 4-methyl-5-(2-trifluoromethyl-phenyl)-1H-pyrrole-3-carboxylic acid methyl ester 
• 5470-49-5 4-methanesulfonylphenylamine 
• 16185-96-9 1-(2-(trifluoromethyl)phenyl)propan-1-one 
• 104384-69-2 2-bromo-1-[2-(trifluoromethyl)phenyl]propan-1-one 
• 1072-53-3 ethyleneglycol sulfate 
• 880779-74-8 4-methyl-N-[4-(methylsulfonyl)phenyl]-5-[2-(trifluoromethyl)-phenyl]-1H-pyrrole-3-carboxamide 

Relevant articles and documents

METHOD FOR PRODUCING PYRROLE DERIVATIVE, AND INTERMEDIATE THEREOF

The present invention provides a method for producing an atropisomer of a pyrrole derivative having excellent mineralocorticoid receptor antagonistic activity, and an intermediate thereof. A method for producing an atropisomer of a pyrrole derivative using a compound represented by (B) [wherein R1 represents a C1-C4 alkyl group, and R2 represents a 2-hydroxyethyl group or a carboxymethyl group] as a production intermediate.

ATROPISOMER OF PYRROLE DERIVATIVE

[Object] A prophylactic or therapeutic agent for a cardiovascular disease is provided. [Means for Resolution] An atropisomer of a compound represented by the following general formula (I): (wherein R1 is a C1-C3 alkyl group or a hydroxy-C1-C3 a