112921-88-7

Basic information

• Product Name: Ethanone, 1-[4-(1-propynyl)phenyl]- (9CI)
• Synonyms: Ethanone, 1-[4-(1-propynyl)phenyl]- (9CI)
• CAS NO: 112921-88-7
• Molecular Formula: C₁₁H₁₀O
• Molecular Weight: 158.1965
• Product Categories: ACETYLGROUP
• Mol File: 112921-88-7.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethanone, 1-[4-(1-propynyl)phenyl]- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[4-(1-propynyl)phenyl]- (9CI)(112921-88-7)
• EPA Substance Registry System: Ethanone, 1-[4-(1-propynyl)phenyl]- (9CI)(112921-88-7)

Safety Data

• Hazardous Substances Data: 112921-88-7(Hazardous Substances Data)

Upstream product

• 99-91-2 para-chloroacetophenone 
• 13329-40-3 4-Iodoacetophenone 
• 64099-82-7 1-propynyltributylstannane 
• 74-99-7 prop-1-yne 
• 42472-69-5 4-ethynylacetophenone 
• 5633-34-1 (benzoylmethylene)dimethylsulfurane 
• 590-93-2 2-Butynoic acid 
• 99-90-1 para-bromoacetophenone 
• 614-45-9 tert-Butyl peroxybenzoate 
• 58335-31-2 1,3-dilithiopropyne 

Downstream Products

• 84325-97-3 methyl 2-(4-acetylphenyl)propanoate 
• 41387-29-5 2-[4-(acetyl)phenyl] propanoic acid 
• 29619-42-9 1,1'-[ethyne-1,2-diylbis(4,1-phenylene)]diethanone 
• 1352848-00-0 (E)-1-(4-(4-hydroxydodec-2-en-3-yl)phenyl)ethanone 
• 1352849-47-8 (E)-2-(3-(4-acetylphenyl)-2-hydroxypent-3-enyl)-isoindoline-1,3-dione 
• 1352848-76-0 (E)-1-(4-(5-(benzyloxy)-4-hydroxypent-2-en-3-yl)phenyl)ethanone 
• 1352850-34-0 (E)-1-(4-(1-hydroxy-1-phenylbut-2-en-2-yl)phenyl)ethanone 
• 1401548-85-3 1-{4-(1,4-dimethylisoquinolin-3-yl)phenyl}ethanone 

Relevant articles and documents

Regiospecific palladium-catalyzed cross-coupling reactions using the operational equivalent of 1,3-dilithiopropyne

A regiospecific palladium-catalyzed cross-coupling reaction using the operational equivalent of the dianion 1,3-dilithiopropyne, with aromatic iodides is reported. This reaction gives high yields of 1-propyn-1-yl-benzenes and 2-(propyn-1-yl)thiophenes in

Enantioselective Addition of α-Nitroesters to Alkynes

By using Rh–H catalysis, we couple α-nitroesters and alkynes to prepare α-amino-acid precursors. This atom-economical strategy generates two contiguous stereocenters, with high enantio- and diastereocontrol. In this transformation, the alkyne undergoes isomerization to generate a RhIII–π-allyl electrophile, which is trapped by an α-nitroester nucleophile. A subsequent reduction with In powder transforms the allylic α-nitroesters to the corresponding α,α-disubstituted α-amino esters.

Multi-Metal-Catalyzed Oxidative Radical Alkynylation with Terminal Alkynes: A New Strategy for C(sp3)-C(sp) Bond Formation

A new way for C(sp3)-C(sp) cross-coupling with terminal alkynes has been developed by using a multi-metal-catalyzed reaction strategy. Alkyl radicals generated from different approaches are able to couple with terminal alkynes by judicious selection of the catalyst combination. This reaction protocol offers an efficient alternative approach for the synthesis of substituted alkynes from terminal alkynes besides traditional Sonogashira coupling. Mechanistic studies have also been carried out to clarify the role of each metal catalyst in the radical alkynylation processes. The reactions were found to go through radical reaction pathways. Synergistic cooperation of the metal catalysts is the key for controlling the reaction selectivity of alkyl radicals toward C(sp3)-C(sp) bond formation.