113495-55-9

Basic information

• Product Name: (2R,3R)-7-Methoxy-3-nitro-2-phenyl-chroman
• CAS NO: 113495-55-9
• Molecular Weight: 285.299
• Mol File: 113495-55-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2R,3R)-7-Methoxy-3-nitro-2-phenyl-chroman(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-7-Methoxy-3-nitro-2-phenyl-chroman(113495-55-9)
• EPA Substance Registry System: (2R,3R)-7-Methoxy-3-nitro-2-phenyl-chroman(113495-55-9)

Safety Data

• Hazardous Substances Data: 113495-55-9(Hazardous Substances Data)

Upstream product

• 105849-85-2 7-methoxy-2-phenyl-3-nitro-2H-chromene 
• 96853-39-3 5-Methoxy-2-(2-nitro-ethyl)-phenol 
• 100-52-7 benzaldehyde 

Downstream Products

• 7478-60-6 7-methoxyflavonol 

Relevant articles and documents

Syntheses of 2-Benzylbenzofuran Derivatives and 2-Aryl-nitrochroman Derivatives from Nitroalkene Precursors

Simple and straightforward methods for the synthesis of 2-benzylbenzofuran, 3-substituted 2-benzylbenzofuran, and 2-aryl-nitrochroman derivatives are described. Benzofurans were generated from nitroalkenes by reduction with NaBH4 followed by a Nef reaction and acid-mediated cyclization, whereas 3-substituted 2-benzylbenzofurans were prepared from nitroalkenes by reactions with Grignard reagents followed by a Nef reaction and an acid-mediated cyclization in a one-pot process. The synthesis of chromans involved a Knoevenagel condensation and the 1,4-diazabicyclo[2.2.2]octane (DABCO) assisted cyclization of β-(2-hydroxyphenyl)-nitroethanes and benzaldehydes, also in a one-pot process. Simple and convenient methods for the synthesis of 2-benzylbenzofuran, 3-substituted 2-benzylbenzofuran, and 2-aryl-nitrochroman derivatives are described.