114081-14-0

Basic information

• Product Name: 2H-Indol-2-one, 1,3-dihydro-3,3-dimethyl-1-(phenylmethyl)-
• CAS NO: 114081-14-0
• Molecular Formula: C17H17NO
• Molecular Weight: 251.328
• Mol File: 114081-14-0.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: 2H-Indol-2-one, 1,3-dihydro-3,3-dimethyl-1-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Indol-2-one, 1,3-dihydro-3,3-dimethyl-1-(phenylmethyl)-(114081-14-0)
• EPA Substance Registry System: 2H-Indol-2-one, 1,3-dihydro-3,3-dimethyl-1-(phenylmethyl)-(114081-14-0)

Safety Data

• Hazardous Substances Data: 114081-14-0(Hazardous Substances Data)

Upstream product

• 122128-46-5 N-benzyl-N-(2-iodophenyl)-2-methylacrylamide 
• 114081-11-7 N-benzyl-2,2-dimethyl-N-(3-pyridyl)-3-butynamide 
• 294642-61-8 N-benzyl-2-bromo-2-methyl-N-phenylpropanamide 
• 887235-17-8 S-(4-pentynyl) N-benzyl-N-(2-isopropenylphenyl)carbamothioate 
• 108-98-5 thiophenol 
• 254759-19-8 N-benzyl-2-methyl-2-bromo-N-cyclohexyl-1-enylpropionamide 
• 490035-95-5 N-benzyl-2-(prop-1-en-2-yl)benzen-amine 
• 324738-55-8 benzyl(2-isopropenyl)carbamyl chloride 
• 76464-99-8 N-benzyl-2-iodoaniline 
• 19155-24-9 3,3-dimethyloxindole 
• 100-39-0 benzyl bromide 
• 1259043-48-5 C₁₇H₁₈BrNO 
• 758640-21-0 N-Benzylaniline 
• 74480-63-0 N-benzyl-2-methyl-N-phenylprop-2-enamide 

Downstream Products

• 19155-24-9 3,3-dimethyloxindole 
• 19501-85-0 1-Benzyl-3,3-dimethylindoline 
• 116916-38-2 1-Benzyl-3,3-dimethylindoline-2-thione 
• 929564-82-9 1-(3-{[tert-butyl(dimethyl)silyl]oxy}-1-phenylpropyl)-3,3-dimethyl-1,3-dihydro-2H-indol-2-one 
• 116916-50-8 2-[1-Benzyl-3,3-dimethyl-1,3-dihydro-indol-(2Z)-ylidene]-propionitrile 
• 116916-49-5 2-[1-Benzyl-3,3-dimethyl-1,3-dihydro-indol-(2E)-ylidene]-propionitrile 
• 151502-77-1 N-(phenylmethyl)-3,3-dimethyl-2-(prop-2'-ene)-2,3-dihydroindole 

Relevant articles and documents

Microwave-assisted intramolecular reductive Heck in aqueous medium: Synthesis of 3,3′-Disubstituted heterocyclic compounds

Heterocyclic products have been accomplished using microwave-assisted [Pd]-catalyzed intramolecular reductive Heck coupling. The protocol found suitable in delivering indolines, oxindoles, and dihydrobenzofurans. Notably, the process was successful in sol

Hydroarylation of Activated Alkenes Enabled by Proton-Coupled Electron Transfer

Hydroarylation of alkenes has been demonstrated to be an atom-economic approach to access functionalized arenes from easily accessible raw materials. Herein, we report a visible light-induced photocatalytic system that enables intramolecular hydroarylation of N-arylacrylamides with high 5-exo-trig selectivity through robust proton-coupled electron transfer (PCET). This mild hydroarylation protocol provides a straightforward entry to structurally valuable oxindoles and complements previously established 6-endo-trig cyclization by photochemical triplet energy transfer (TET).

DMF-Promoted Redox-Neutral Ni-Catalyzed Intramolecular Hydroarylation of Alkene with Simple Arene

A redox-neutral Ni-catalyzed intramolecular hydroarylation of alkene with simple arene has been developed, in which DMF played a proton shuttle role in facilitating the intramolecular coupling, avoiding the use of additional reductants and oxidants. A series of oxindoles with a quaternary center were obtained in up to 99% yield.

A tethering directing group strategy for ruthenium-catalyzed intramolecular alkene hydroarylation

We report a new catalyst design for N-heterocycle synthesis that utilizes an alkene-tethered amide moiety as a directing group for aromatic C-H activation. This tethering directing group strategy is demonstrated in a ruthenium-catalyzed intramolecular alk