1152313-77-3Relevant articles and documents
Synthesis of Bis(oxazoline) Ligands Possessing C-5 gem-Disubstitution and Their Application in Asymmetric Friedel-Crafts Alkylations
O'Reilly, Steven,Aylward, Miriam,Keogh-Hansen, Caoimhe,Fitzpatrick, Brian,McManus, Helen A.,Müller-Bunz, Helge,Guiry, Patrick J.
, p. 10177 - 10186 (2015/11/03)
A series of eight novel bis(oxazoline) ligands incorporating gem-disubstitution on one of the oxazoline rings were prepared from (S)-valine. These ligands are designed as a cost-effective alternative to similar ligands possessing an oxazolinyl C(5)-tert-b
Use of 5,5-(dimethyl)-i-Pr-PHOX as a practical equivalent to t-Bu-PHOX in asymmetric catalysis
Belanger, Etienne,Pouliot, Marie-France,Paquin, Jean-Francois
supporting information; experimental part, p. 2201 - 2204 (2009/09/28)
The use of 5,5-(dimethyl)-i-Pr-PHOX as a practical equivalent of t-Bu-PHOX in asymmetric catalysis is reported. This new member of the phosphinooxazoline (PHOX) ligand family behaves similarly in terms of stereoinduction to t-Bu-PHOX with the key advantage of being readily accessible as both enantiomers starting from either(S)- or (R)-valine.