1152313-76-2 Usage
Description
(4S)-2-[2-(diphenylphosphino)phenyl]-4,5-dihydro-5,5-diMethyl-4-(1-Methylethyl)-oxazole is a complex organic compound with a unique molecular structure. It is characterized by its dihydro-oxazole backbone, which is substituted with a diphenylphosphino group on the phenyl ring. (4S)-2-[2-(diphenylphosphino)phenyl]-4,5-dihydro-5,5-diMethyl-4-(1-Methylethyl)-oxazole is of interest due to its potential applications in various chemical and pharmaceutical processes.
Uses
Used in Asymmetric Catalysis:
(4S)-2-[2-(diphenylphosphino)phenyl]-4,5-dihydro-5,5-diMethyl-4-(1-Methylethyl)-oxazole is used as a practical equivalent to t-Bu-PHOX in asymmetric catalysis. Its unique molecular structure allows it to serve as an effective catalyst in various chemical reactions, enhancing the enantioselectivity and efficiency of the process.
Used in Pd-Catalyzed Asymmetric Transformations:
(4S)-2-[2-(diphenylphosphino)phenyl]-4,5-dihydro-5,5-diMethyl-4-(1-Methylethyl)-oxazole is also utilized in the design, synthesis, and application of potential substitutes for t-Bu-Phosphinooxazoline in Pd-catalyzed asymmetric transformations. Its ability to improve the enantioselectivity in these reactions makes it a valuable tool in the development of new and improved chemical processes.
Used in the Pd-Catalyzed Allylation Reaction of Fluorinated Allyl Enol Carbonates:
(4S)-2-[2-(diphenylphosphino)phenyl]-4,5-dihydro-5,5-diMethyl-4-(1-Methylethyl)-oxazole is used as a catalyst in the Pd-catalyzed allylation reaction of fluorinated allyl enol carbonates. Its presence in the reaction can lead to improved enantioselectivity, which is crucial for the production of chiral compounds with specific biological activities.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (4S)-2-[2-(diphenylphosphino)phenyl]-4,5-dihydro-5,5-diMethyl-4-(1-Methylethyl)-oxazole may be used as a key intermediate in the synthesis of various drugs and drug candidates. Its unique properties and reactivity can contribute to the development of new therapeutic agents with improved efficacy and selectivity.
Used in Chemical Research and Development:
(4S)-2-[2-(diphenylphosphino)phenyl]-4,5-dihydro-5,5-diMethyl-4-(1-Methylethyl)-oxazole is also valuable in the field of chemical research and development, where it can be used to explore new reaction pathways, develop novel catalysts, and create innovative synthetic methods. Its unique structure and reactivity make it a promising candidate for further investigation and application in various chemical processes.
Check Digit Verification of cas no
The CAS Registry Mumber 1152313-76-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,5,2,3,1 and 3 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1152313-76:
(9*1)+(8*1)+(7*5)+(6*2)+(5*3)+(4*1)+(3*3)+(2*7)+(1*6)=112
112 % 10 = 2
So 1152313-76-2 is a valid CAS Registry Number.
1152313-76-2Relevant articles and documents
Design, synthesis, and applications of potential substitutes of t-Bu-phosphinooxazoline in Pd-catalyzed asymmetric transformations and their use for the improvement of the enantioselectivity in the Pd-catalyzed allylation reaction of fluorinated allyl enol carbonates
Belanger, Etienne,Pouliot, Marie-France,Courtemanche, Marc-Andre,Paquin, Jean-Francois
, p. 317 - 331 (2012/02/15)
The design, synthesis, and applications of potential substitutes of t-Bu-PHOX in asymmetric catalysis is reported. The design relies on the incorporation of geminal substituents at C5 in combination with a substituent at C4 other than t-butyl (i-Pr, i-Bu, or s-Bu). Most of these new members of the PHOX ligand family behave similarly in terms of stereoinduction to t-Bu-PHOX in three palladium-catalyzed asymmetric transformations. Electronically modified ligands were also prepared and used to improve the enantioselectivity in the Pd-catalyzed allylation reaction of fluorinated allyl enol carbonates.
