116-26-7 Usage
Description
SAFRANAL, a monoterpenoid formally derived from beta-cyclocitral by dehydrogenation, is a compound that occurs naturally as a glucoside (picrocrocin) in saffron. It is primarily responsible for the aroma of saffron and is known for its characteristic saffron-like odor and taste. SAFRANAL also possesses anticonvulsant, anticancer, and antidepressant properties.
Uses
Used in Flavor and Fragrance Industry:
SAFRANAL is used as a flavoring agent for its woody, medicinal, spicy, and camphoraceous taste with a fruity and herbal nuance. It is also utilized as a fragrance component due to its distinctive saffron-like odor.
Used in Pharmaceutical Applications:
SAFRANAL is used as an anticonvulsant agent, acting as an agonist at GABAA receptors, which helps in managing seizures and other related conditions.
Used in Anticancer Applications:
SAFRANAL is used as an anticancer agent, exhibiting potential benefits in the treatment of various types of cancer.
Used in Antidepressant Applications:
SAFRANAL is used as an antidepressant agent, helping to alleviate symptoms of depression and improve overall mental health.
Used in the Food Industry:
SAFRANAL is used as a natural additive in the food industry to enhance the flavor and aroma of various products, taking advantage of its taste threshold values and characteristic saffron-like taste.
Preparation
By acid hydrolysis of picrocrocin, the bitter principle in saffron; by catalytic dehydrogenation of β-cyclocitral or
α-cyclogeranic acid with selenium dioxide.
Flammability and Explosibility
Notclassified
Check Digit Verification of cas no
The CAS Registry Mumber 116-26-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,1 and 6 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 116-26:
(5*1)+(4*1)+(3*6)+(2*2)+(1*6)=37
37 % 10 = 7
So 116-26-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H14O/c1-8-5-4-6-10(2,3)9(8)7-11/h4-5,7H,6H2,1-3H3
116-26-7Relevant articles and documents
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Kametani,T. et al.
, p. 1128 - 1129 (1979)
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γ-Pyronene, a synthon derived from saffron and intermediary precursor of synthesis of forskolin and strigol
Boulin,Arreguy-San Miguel,Delmond
, p. 2753 - 2762 (2007/10/03)
γ-Pyronene, a terpenic synthon available from myrcene, is an excellent raw material for the preparation of numerous intermediates used in the synthesis of perfumes, retinoids and biological derivatives such as forskolin or strigol.
The chemistry of thujone. XVI. Versatile and efficient routes to safronitrile, β-cyclogeranonitrile, β-cyclocitral, damascones, and their analogues
Kutney, James P.,Gunning, Philip J.,Clewley, Robin G.,Somerville, John,Rettig, Steven J.
, p. 2094 - 2114 (2007/10/02)
Thujone, a waste by-product of the Canadian forest industry, has been utilized as a starting material to develop a versatile synthetic route to the damascones (rose oil ketones) and related analogues.The synthetic sequence provides a route to β-cyclocitral (45), the latter having been previously converted to β-damascone (2).In addition, thujone-drived intermediates are converted to β-damascenone (48) and to intermediates that can be utilized for the preparation of damascone analogues.In conjunction with the above, an efficient route to safronitrile (42), β-cyclogeranonitrile (43), and β-cyclocitral (45) from 2,6-dimethylcyclohexanone has been developed.In summary, these studies afford an attractive versatile route to these important perfumery materials.