116922-17-9

Basic information

• Product Name: ethyl α-ethoxy-2-carbamoylcinnamate
• Synonyms: ethyl α-ethoxy-2-carbamoylcinnamate
• CAS NO: 116922-17-9
• Molecular Weight: 263.293
• Mol File: 116922-17-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl α-ethoxy-2-carbamoylcinnamate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl α-ethoxy-2-carbamoylcinnamate(116922-17-9)
• EPA Substance Registry System: ethyl α-ethoxy-2-carbamoylcinnamate(116922-17-9)

Safety Data

• Hazardous Substances Data: 116922-17-9(Hazardous Substances Data)

Upstream product

• 4387-36-4 2-iodobenzonitrile 
• 22121-86-4 ethyl 2-ethoxyacrylate 
• 116922-16-8 ethyl α-ethoxy-2-cyanocinnamate 

Downstream Products

• 94726-24-6 ethyl 1,2-dihydro-1-oxo-isoquinoline-3-carboxylate 

Relevant articles and documents

CONDENSED HETEROAROMATIC RING SYSTEMS. XIV. CYCLIZATION OF ORTHO-SUBSTITUTED α-ETHOXYCINNAMATES TO SOME HETEROAROMATICS

The reaction of 2-iodoaniline with ethyl 2-ethoxyacrylate in the presence of palladium-charcoal gave 3-ethoxy-2(1H)-quinolinone, and the reaction of 2-iodoacetanilide with the same reagent yielded ethyl 2-acetylamino-α-ethoxycinnamate which was cyclized to ethyl indole-2-carboxylate under acidic conditions.On the other hand, the palladium-catalyzed reaction of 2-iodobenzonitrile and ethyl 2-iodobenzoate afforded the corresponding cinnamates which were transformed into isoquinoline and isocoumarin derivatives.