118133-69-0

Basic information

• Product Name: (3S) methyl 3-hydroxy-5-phenylpentanoate
• Synonyms: (3S) methyl 3-hydroxy-5-phenylpentanoate
• CAS NO: 118133-69-0
• Molecular Weight: 208.257
• Mol File: 118133-69-0.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: (3S) methyl 3-hydroxy-5-phenylpentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (3S) methyl 3-hydroxy-5-phenylpentanoate(118133-69-0)
• EPA Substance Registry System: (3S) methyl 3-hydroxy-5-phenylpentanoate(118133-69-0)

Safety Data

• Hazardous Substances Data: 118133-69-0(Hazardous Substances Data)

Upstream product

• 104-53-0 3-phenyl-propionaldehyde 
• 36850-80-3 [(1-methoxyvinyl)oxy]trimethylsilane 
• 77086-38-5 ketene t-butyldimethylsilyl methyl acetal 
• 22348-97-6 methyl 3-oxotetradecanoate 
• 768-56-9 4-Phenylbut-1-ene 
• 16695-14-0 Malonic acid monomethyl ester 
• 105-45-3 acetoacetic acid methyl ester 
• 118133-59-8 (2S)-1-<(S)-p-chlorophenylsulfinyl>-4-phenyl-2-butanol 
• 118133-49-6 (S)-1-(p-chlorophenylsulfinyl)-4-phenyl-2-butanone 
• 100-39-0 benzyl bromide 
• 129880-16-6 3-hydroxy-5-phenyl-pentanoic acid methyl ester 
• 918148-53-5 (S)-3-Acetoxy-5-phenyl-pentanoic acid methyl ester 
• 30414-58-5 methyl 3-oxo-5-phenylpentanoate 
• 30568-00-4 dianion of methyl acetoacetate 

Downstream Products

• 182950-96-5 (6S)-6-(2-phenylethyl)dihydropyran-2,4⁽³⁾-dione 
• 587-63-3 7,8-dihydrokawain 
• 182950-95-4 (S)-5-hydroxy-3-oxo-7-phenyl-heptanoic acid tert-butyl ester 

Relevant articles and documents

Asymmetric Palladium-Catalyzed Oxycarbonylation of Terminal Alkenes: Efficient Access to β-Hydroxy Alkylcarboxylic Acids

A novel PdII-catalyzed enantioselective oxycarbonylation of alkenes has been established. The ligand with an ethyl group at the C-6 position of Pyox plays a significant role in the intermolecular oxypalladation process, leading to high reactivity and excellent enantioselective control. Compared to the conventional methods, the reaction itself features alkenes as easily prepared starting materials, mild and operationally simple reaction conditions, and insensitivities to air and water. Moreover, this method allows for broad alkene substrate scope, excellent regio- and enantioselectivities, scalabilities and a wide array of applications, and provides a useful route for the convenient and straightforward synthesis of chiral β-hydroxy alkylcarboxylic acids/esters.

Synthesizing method of chiral beta hydroxyl acid ester compound

The invention discloses a synthesizing method of a chiral beta hydroxyl acid ester compound. The synthesizing method is characterized by including: subjecting an aldehyde compound and monoalkyl malonate serving as the raw materials to direct and sufficien

Chemoenzymatic synthesis of enantiomerically enriched kavalactones

Lipase-mediated kinetic resolution of methyl-3-hydroxy-5-phenylpentanoate and (6E)-ethyl 5-hydroxy-3-oxo-7-phenylhept-6-enoate is described in high enantiomeric excess and good yields. The effect of different lipases in different solvents has been screened using different acylating agents. This protocol has been extended for the preparation of enantiomerically pure biologically important kavalactones.