182950-96-5

Basic information

• Product Name: 2H-Pyran-2,4(3H)-dione, dihydro-6-(2-phenylethyl)-, (S)-
• CAS NO: 182950-96-5
• Molecular Formula: C13H14O3
• Molecular Weight: 218.252
• Mol File: 182950-96-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2H-Pyran-2,4(3H)-dione, dihydro-6-(2-phenylethyl)-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyran-2,4(3H)-dione, dihydro-6-(2-phenylethyl)-, (S)-(182950-96-5)
• EPA Substance Registry System: 2H-Pyran-2,4(3H)-dione, dihydro-6-(2-phenylethyl)-, (S)-(182950-96-5)

Safety Data

• Hazardous Substances Data: 182950-96-5(Hazardous Substances Data)

Upstream product

• 1443322-44-8 methyl 3-[(2S)-2-hydroxy-4-phenylbutyl]but-3-enoate 
• 104-53-0 3-phenyl-propionaldehyde 
• 100-39-0 benzyl bromide 
• 157732-87-1 (4S)-2,2-dimethyl-4-(2-phenylethyl)-1,3-dioxolane 
• 152203-65-1 (4S)-2,2-dimethyl-4-styryl-1,3-dioxolane 
• 118629-73-5 (S)-2-hydroxy-4-phenylbutyl 4-methylbenzenesulfonate 
• 125103-96-0 (S)-5-phenyl-3-hydroxypentanenitrile 
• 124988-64-3 (S)-4-phenyl-1,2-butanediol 
• 1449-46-3 benzyltriphenylphosphonium bromide 
• 118133-69-0 (3S) methyl 3-hydroxy-5-phenylpentanoate 
• 129880-16-6 3-hydroxy-5-phenyl-pentanoic acid methyl ester 
• 30414-58-5 methyl 3-oxo-5-phenylpentanoate 
• 918148-53-5 (S)-3-Acetoxy-5-phenyl-pentanoic acid methyl ester 
• 862464-32-2 methyl (5S)-5-hydroxy-3-oxo-7-phenylheptanoate 

Downstream Products

• 587-63-3 7,8-dihydrokawain 

Relevant articles and documents

Enantioselective synthesis of (+)-(S)-7,8-dihydrokavain and (4R,6R)-4-hydroxy-6-(2-phenylethyl)tetrahydro-2H-pyran-2-one, lactone analog of compactin and mevinolin

A simple and efficient asymmetric synthesis was performed of (+)-(S)-7,8-dihydrokanian and (4R,6R)-4-hydroxy-6-(2-phenylethyl)tetrahydro-2H- pyran-2-one involving Keck allylation in the key stage of building up the carbon scaffold of the target molecules.

A total synthesis of (+)- and (-)-dihydrokavain with a sonochemical blaise reaction as the key step

Starting from 2,3-O-isopropylidene-D-glyceraldehyde (2) as chiral material, the naturally occurring (S)-(+)-dihydrokavain (1a) was synthesized by a procedure that involves a sonochemical Blaise reaction as the key step. The absolute configuration of (S)-(

Enantioselective synthesis of (+)- and (-)-dihydrokawain

The first asymmetric synthesis of (+)- and (-)-dihydrokawain, an α-dihydropyrone isolated from the roots of Piper mythisticum, is reported. (+)-Dihydrokawain is the natural product and is of S-configuration.