120578-05-4

Basic information

• Product Name: 3-[{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-(2-dimethylcarbamoyl-ethylsulfanyl)-methylsulfanyl]-N,N-dimethyl-propionamide
• Synonyms: 3-[{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-(2-dimethylcarbamoyl-ethylsulfanyl)-methylsulfanyl]-N,N-dimethyl-propionamide
• CAS NO: 120578-05-4
• Molecular Weight: 542.166
• Mol File: 120578-05-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-[{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-(2-dimethylcarbamoyl-ethylsulfanyl)-methylsulfanyl]-N,N-dimethyl-propionamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-(2-dimethylcarbamoyl-ethylsulfanyl)-methylsulfanyl]-N,N-dimethyl-propionamide(120578-05-4)
• EPA Substance Registry System: 3-[{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-(2-dimethylcarbamoyl-ethylsulfanyl)-methylsulfanyl]-N,N-dimethyl-propionamide(120578-05-4)

Safety Data

• Hazardous Substances Data: 120578-05-4(Hazardous Substances Data)

Upstream product

• 92065-71-9 N,N-dimethyl-3-mercaptopropionamide 
• 120578-03-2 (E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde 
• 2680-03-7 N,N-Dimethylacrylamide 
• 626-19-7 Isophthalaldehyde 
• 4965-33-7 2-methyl-7-chloroquinoline 
• 2935-90-2 Methyl 3-mercaptopropionate 
• 120578-06-5 3-({3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-trimethylsilanyloxy-methylsulfanyl)-N,N-dimethyl-propionamide 

Relevant articles and documents

Synthesis of Unsymmetrical Dithioacetals: An Efficient Synthesis of a Novel LTD4 Antagonist, L-660,711

An efficient four-step synthesis of the potent LTD4 antagonist L-660,711 (1) is described.The key step involves selective conversion of aldehyde 2 to the unsymmetrical dithioacetal 7, via O-trimethylsilyl hemithioacetal 10.This specific cleavage of the carbon-oxygen bond of a mixed O,S-acetal permits the unprecedented synthesis of unsymmetrical dithioacetals.