120578-06-5

Basic information

• Product Name: 3-({3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-trimethylsilanyloxy-methylsulfanyl)-N,N-dimethyl-propionamide
• Synonyms: 3-({3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-trimethylsilanyloxy-methylsulfanyl)-N,N-dimethyl-propionamide
• CAS NO: 120578-06-5
• Molecular Weight: 499.149
• Mol File: 120578-06-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-({3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-trimethylsilanyloxy-methylsulfanyl)-N,N-dimethyl-propionamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-({3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-trimethylsilanyloxy-methylsulfanyl)-N,N-dimethyl-propionamide(120578-06-5)
• EPA Substance Registry System: 3-({3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-trimethylsilanyloxy-methylsulfanyl)-N,N-dimethyl-propionamide(120578-06-5)

Safety Data

• Hazardous Substances Data: 120578-06-5(Hazardous Substances Data)

Upstream product

• 2680-03-7 N,N-Dimethylacrylamide 
• 4965-33-7 2-methyl-7-chloroquinoline 
• 120578-03-2 (E)-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde 
• 92065-71-9 N,N-dimethyl-3-mercaptopropionamide 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 626-19-7 Isophthalaldehyde 

Downstream Products

• 135028-15-8 (E)-5-(3-(2-(7-chloroquinolin-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoic acid 
• 120385-96-8 dimethyl 5-<3-<2-(7-chloro-2-quinolinyl)-(E)-ethenyl>phenyl>-4,6-dithianonanedioate 
• 120443-15-4 (+)-methyl 5-(3-(2-(7-chloroquinoline-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoate 
• 120578-05-4 3-[{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-(2-dimethylcarbamoyl-ethylsulfanyl)-methylsulfanyl]-N,N-dimethyl-propionamide 

Relevant articles and documents

Synthesis of Unsymmetrical Dithioacetals: An Efficient Synthesis of a Novel LTD4 Antagonist, L-660,711

An efficient four-step synthesis of the potent LTD4 antagonist L-660,711 (1) is described.The key step involves selective conversion of aldehyde 2 to the unsymmetrical dithioacetal 7, via O-trimethylsilyl hemithioacetal 10.This specific cleavage of the carbon-oxygen bond of a mixed O,S-acetal permits the unprecedented synthesis of unsymmetrical dithioacetals.