1240125-28-3

Basic information

• Product Name: C₃₁H₃₈N₂O₈S₂
• CAS NO: 1240125-28-3
• Molecular Weight: 630.783
• Mol File: 1240125-28-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: C₃₁H₃₈N₂O₈S₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₁H₃₈N₂O₈S₂(1240125-28-3)
• EPA Substance Registry System: C₃₁H₃₈N₂O₈S₂(1240125-28-3)

Safety Data

• Hazardous Substances Data: 1240125-28-3(Hazardous Substances Data)

Upstream product

• 146368-08-3 1-(5-carboxypentyl)-2,3,3-trimethyl-3H-indolium-5-sulfonate 
• 122-51-0 orthoformic acid triethyl ester 
• 146368-07-2 1-Ethyl-2,3,3-Trimethylindolenineninium 5-Sulfone 
• 4224-70-8 6-bromohexanoic acid 
• 1251915-08-8 C₂₂H₂₄N₂O₄S 
• 98-71-5 4-hydrazino-benzenesulfonic acid 
• 563-80-4 3-methyl-butan-2-one 
• 132557-72-3 2,3,3-trimethylindole-5-sulfonic acid 
• 146368-09-4 C₂₀H₂₂N₂O₃S 
• 146368-09-4 (E)-1-ethyl-3,3-dimethyl-2-(2-(phenylamino)vinyl)-3H-indol-1-ium-5-sulfonate 

Downstream Products

• 146368-16-3 3H-indolium-1-(5-carboxypentyl)-2-[(1E,3E)-3-(1-ethyl-1,3-dihydro-3,3-dimethyl-5-sulfo-2H-indol-2-ylidene)-1-propenyl]-3,3-dimethyl-5-sulfo-, inner salt, succinimidyl ester 
• 1240125-45-4 Cy₃ N-hydroxysuccinimidyl ester 

Relevant articles and documents

Sulfo - Cy3 carboxylic acid fluorescent dye and preparation process thereof

The invention relates to a sulfo - Cy3 carboxylic acid fluorescent dye and a preparation process thereof, wherein the synthesized sulfo - Cy3 carboxylic acid has fluorescent quantum yield. At the same time, the high-emission high-excitation wavelength and is easily dissolved in water physical and chemical property stability points, and simultaneously, a single condensation target product needs to be selectively generated when the indole α-position methyl activity is achieved through simultaneous construction of the benzylindole two-side branch chains and high in yield, and C18 column separation is avoided.

FLUORESCENCE COMPOUNDS AND PREPARATION METHOD THEREOF

Provided is a fluorescent compound represented by the following [Chemical Formula 1] and a method for preparing the same: wherein each of X, Y, R1, R2, R3 and n is the same as defined in the specification.

Synthesis of PEG derivatives bearing aminophenyl and their application for liquid-phase synthesis of water-soluble unsymmetrical cyanine dyes

The synthesis and NMR characterization of soluble PEG-supported polymers were described, and their subsequent application for liquid-phase synthesis of water-soluble cyanine dyes was also studied. Nucleophilic substitution of tosylation of PEG 16 with 1,3-bis(4-nitrophenoxy)-2-propanol 15 under basic conditions, followed by nitro group reduction, gave PEG-bound aminophenyl 18. Another PEG-bound aminophenyl 28 was prepared by condensation reaction of PEG-bound pentaerythritol 25 and 4-aminobenzoic acid followed by the cleavage of BOC group. Subsequent loading and activation of sulfoindoleninium to PEG derivatives 18 or 28 were achieved via simple strategies. Cyanine dyes were released by the attack of heterocyclic carbon nucleophile and the cleavage of PEG-bound hemicyanine without the chromatographic separation. The efficient, facile, and practical approaches appear to be robust and versatile strategies to deliver not only indocyanine dyes but also benzoindocyanine dyes.