1254344-23-4

Basic information

• Product Name: 5-formyl-4-phenyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
• CAS NO: 1254344-23-4
• Molecular Weight: 243.329
• Mol File: 1254344-23-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-formyl-4-phenyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-formyl-4-phenyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine(1254344-23-4)
• EPA Substance Registry System: 5-formyl-4-phenyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine(1254344-23-4)

Safety Data

• Hazardous Substances Data: 1254344-23-4(Hazardous Substances Data)

Upstream product

• 30433-91-1 [2-(2-thyenyl)ethyl]amine 
• 100-52-7 benzaldehyde 

Downstream Products

• 91477-84-8 4-phenyl-4,5,6,7-tetrahydrothieno[3,2-c]-pyridine 

Relevant articles and documents

An efficient and convenient synthesis of 4,5,6,7-tetrahydrothieno[3,2-c] pyridines by a modified Pictet-Spengler reaction via a formyliminium ion intermediate

A synthesis of N-formyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridines (5) was achieved in a highly efficient manner via trifluoroacetic acid catalyzed cyclization of formyliminium ion (4), which was produced by imination of 2-(2-thienyl)ethylamine (1) and a carbonyl compound (2) using titanium(IV) tetraisopropoxide followed by formylation with acetic-formic anhydride in a one-pot procedure. This modified Pictet-Spengler reaction provides a convenient method for preparing 4,5,6,7-tetahydrothieno[3,2-c]pyridines (6) possessing various substituents at C-4. The Japan Institute of Heterocyclic Chemistry.