1258208-40-0Relevant articles and documents
Kinetic resolution of homoaldols via catalytic asymmetric transacetalization
Coric, Ilija,Mueller, Steffen,List, Benjamin
supporting information; experimental part, p. 17370 - 17373 (2011/02/23)
The highly enantioselective kinetic resolution of homoaldols via a transacetalization reaction has been achieved. A novel phosphoric acid, STRIP, based on a spirocyclic 1,1′-spirobiindane backbone was designed and identified as a superior catalyst for this transformation. Remarkably, both secondary and tertiary homoaldols gave equally excellent results.