1258839-95-0

Basic information

• Product Name: ethyl 2-((dimethylamino)methyl)-5-fluorobenzoate
• CAS NO: 1258839-95-0
• Molecular Weight: 225.263
• Mol File: 1258839-95-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 2-((dimethylamino)methyl)-5-fluorobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-((dimethylamino)methyl)-5-fluorobenzoate(1258839-95-0)
• EPA Substance Registry System: ethyl 2-((dimethylamino)methyl)-5-fluorobenzoate(1258839-95-0)

Safety Data

• Hazardous Substances Data: 1258839-95-0(Hazardous Substances Data)

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 64-17-5 ethanol 
• 201230-82-2 carbon monoxide 
• 702-11-4 4-fluoro-N,N-dimethylbenzylamine 

Relevant articles and documents

LiCl-Promoted Pd(ii)-catalyzed ortho carbonylation of N,N- dimethylbenzylamines

Palladium-catalyzed highly regioselective carbonylation of substituted N,N-dimethylbenzylamines with the assistance of LiCl was developed. The ortho-functionalized N,N-dimethylbenzylamine was further transformed into ortho-methyl benzoate under mild conditions. These two transformations could be combined into one pot to produce the desired product in moderate yield. Applications of this methodology to synthesize the fragments of variolaric acid were also studied.