130982-85-3

Basic information

• Product Name: (S)-(-)-temafloxacin
• Synonyms: (S)-(-)-temafloxacin
• CAS NO: 130982-85-3
• Molecular Weight: 417.387
• Mol File: 130982-85-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-(-)-temafloxacin(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(-)-temafloxacin(130982-85-3)
• EPA Substance Registry System: (S)-(-)-temafloxacin(130982-85-3)

Safety Data

• Hazardous Substances Data: 130982-85-3(Hazardous Substances Data)

Upstream product

• 13264-88-5 (S)-(-)-2-methylpiperazine dihydrochloride 
• 103995-01-3 6,7-difluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-3-quinoline-carboxylic acid 
• 129322-83-4 2',4',5'-trifluoroacetophenone 
• 108115-67-9 ethyl 3-(2,4-difluoroanilino)-2-(2,4,5-trifluorobenzoyl)acrylate 
• 108138-17-6 6,7-difluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid ethyl ester 
• 98349-24-7 ethyl 2,4,5-trifluorobenzoylacetate 
• 88419-56-1 2,4,5-trifluorobenzoyl chloride 
• 446-17-3 2,4,5-trifluorobenzoic acid 
• 367-23-7 1,2,4-trifluorobenzene 

Relevant articles and documents

Synthesis, Antibacterial Activities, and Pharmacological Properties of Enantiomers of Temafloxacin Hydrochloride

Temafloxacin hydrochloride is a potent member of the 4-pyridone-3-carboxylic acid class of antibacterial agents and is currently under clinical development as a broad-spectrum antimicrobial agent.It is a racemate having a chiral center at the C3 of the 7-piperazin-1-yl group.The two enantiomers were synthesized and tested for their antibacterial activities.Although no difference in in vitro antibacterial activities was observed, a minor difference in in vivo antibacterial activities was observed.However, they both exhibited similar pharmacological profiles.