131564-69-7 Usage
Description
(-)-O-Demethylmetoprolol is a chemical compound and a metabolite of the beta-blocker medication metoprolol. It is formed in the body through the process of demethylation, where a methyl group is removed from metoprolol, resulting in (-)-O-Demethylmetoprolol. This metabolite possesses similar beta-blocking activity to metoprolol and is eliminated from the body through urinary excretion. It plays a crucial role in the pharmacokinetics and pharmacodynamics of metoprolol, and its measurement in the body can provide valuable insights into the metabolism and elimination of metoprolol in patients. (-)-O-Demethylmetoprolol is an important chemical for understanding the actions and effects of metoprolol in the body.
Uses
Used in Pharmaceutical Industry:
(-)-O-Demethylmetoprolol is used as a metabolite of metoprolol for understanding the pharmacokinetics and pharmacodynamics of the beta-blocker medication. Its measurement in the body can provide insights into the metabolism and elimination of metoprolol in patients, which is essential for optimizing dosage and treatment plans.
Used in Medical Research:
(-)-O-Demethylmetoprolol is used as a research compound to study the effects of metoprolol on the body. It helps researchers to understand the mechanisms of action and the therapeutic effects of metoprolol, as well as its potential side effects and interactions with other medications.
Used in Drug Development:
(-)-O-Demethylmetoprolol is used in the development of new beta-blocker medications. By studying the properties and effects of (-)-O-Demethylmetoprolol, researchers can design and develop new drugs with improved efficacy, safety, and pharmacokinetic profiles.
Used in Toxicology Studies:
(-)-O-Demethylmetoprolol is used in toxicology studies to evaluate the safety and potential side effects of metoprolol and other beta-blocker medications. Its measurement in the body can help to determine the risk of adverse effects and guide the development of safer and more effective treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 131564-69-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,5,6 and 4 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 131564-69:
(8*1)+(7*3)+(6*1)+(5*5)+(4*6)+(3*4)+(2*6)+(1*9)=117
117 % 10 = 7
So 131564-69-7 is a valid CAS Registry Number.
131564-69-7Relevant articles and documents
Technique for synthesizing levorotatory betaxolol hydrochloride (by machine translation)
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Paragraph 0009, (2017/03/17)
The invention discloses a technique for synthesizing levorotatory betaxolol hydrochloride, the process adopts to hydroxy phenylacetic alcohol and R- epoxy halogen propane is used as starting material, under certain conditions after alkylation, amination,
