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1351987-19-3

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1351987-19-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1351987-19-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,1,9,8 and 7 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1351987-19:
(9*1)+(8*3)+(7*5)+(6*1)+(5*9)+(4*8)+(3*7)+(2*1)+(1*9)=183
183 % 10 = 3
So 1351987-19-3 is a valid CAS Registry Number.

1351987-19-3Downstream Products

1351987-19-3Relevant articles and documents

Convergent Synthesis of the Renin Inhibitor Aliskiren Based on C5-C6 Disconnection and CO2H-NH2 Equivalence

Cini, Elena,Banfi, Luca,Barreca, Giuseppe,Carcone, Luca,Malpezzi, Luciana,Manetti, Fabrizio,Marras, Giovanni,Rasparini, Marcello,Riva, Renata,Roseblade, Stephen,Russo, Adele,Taddei, Maurizio,Vitale, Romina,Zanotti-Gerosa, Antonio

, p. 270 - 283 (2016)

A novel synthesis of the renin inhibitor aliskiren based on an unprecedented disconnection between C5 and C6 was developed, in which the C5 carbon acts as a nucleophile and the amino group is introduced by a Curtius rearrangement, which follows a simultaneous stereocontrolled generation of the C4 and C5 stereogenic centers by an asymmetric hydrogenation. Operational simplicity, step economy, and a good overall yield makes this synthesis amenable to manufacture on scale.

PROCESS FOR PRODUCING ALISKIREN

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Page/Page column 18-19, (2011/12/14)

A new route of synthesis of the compound Aliskiren of formula (I), used in the treatment of hypertension, is described.

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