137869-22-8

Basic information

• Product Name: 2-Phenylnaphthalene-1-carboxaldehyde
• Synonyms: 2-Phenylnaphthalene-1-carboxaldehyde
• CAS NO: 137869-22-8
• Molecular Formula: C₁₇H₁₂O
• Molecular Weight: 232.27658
• Mol File: 137869-22-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Phenylnaphthalene-1-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Phenylnaphthalene-1-carboxaldehyde(137869-22-8)
• EPA Substance Registry System: 2-Phenylnaphthalene-1-carboxaldehyde(137869-22-8)

Safety Data

• Hazardous Substances Data: 137869-22-8(Hazardous Substances Data)

Upstream product

• 137869-15-9 2-(2-phenyl-1-naphthyl)oxazoline 
• 51439-58-8 2-methoxy-1-naphthoic acid chloride 
• 3401-47-6 1-bromo-2-methoxynaphthalene 
• 947-62-6 2-methoxy-1-naphthoic acid 
• 94321-75-2 2-Methoxy-naphthalene-1-carboxylic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide 
• 94321-29-6 2-(2-methoxy-1-naphthyl)oxazoline 
• 5392-12-1 2-methoxy-1-naphthaldehyde 
• 100-58-3 phenylmagnesium bromide 

Downstream Products

• 1375801-13-0 1-(2-iodovinyl)-2-phenylnaphthalene 
• 218-01-9 chrysene 

Relevant articles and documents

Regio- and Chemoselective Kumada-Tamao-Corriu Reaction of Aryl Alkyl Ethers Catalyzed by Chromium under Mild Conditions

Acting as an environmentally benign synthetic tool, the cross-coupling reactions with aryl ethers via C-O bond activation have attracted broad interest. However, the functionalizations of C-O bonds are mainly limited to nickel catalysis, and selectivity has long been a prominent challenge when several C-O bonds are present in the one molecule. We report here the first chromium-catalyzed selective cross-coupling reactions of aryl ethers with Grignard reagents by the cleavage of C-O(alkyl) bonds. Diverse transformations were achieved using simple, inexpensive chromium(II) precatalyst combining imino auxiliary at room temperature. It offers a new avenue for buildup functionalized aromatic aldehydes with high efficiency and selectivity.