138371-97-8

Basic information

• Product Name: (1SR,2SR) N-tert-butoxycarbonyl-2-(β-hydroxy-β-phenylethyl)piperidine
• CAS NO: 138371-97-8
• Molecular Weight: 305.417
• Mol File: 138371-97-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (1SR,2SR) N-tert-butoxycarbonyl-2-(β-hydroxy-β-phenylethyl)piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: (1SR,2SR) N-tert-butoxycarbonyl-2-(β-hydroxy-β-phenylethyl)piperidine(138371-97-8)
• EPA Substance Registry System: (1SR,2SR) N-tert-butoxycarbonyl-2-(β-hydroxy-β-phenylethyl)piperidine(138371-97-8)

Safety Data

• Hazardous Substances Data: 138371-97-8(Hazardous Substances Data)

Upstream product

• 119910-09-7 N-tert-butoxycarbonyl-2-ethoxypiperidine 
• 85908-96-9 2-oxopiperidine-1-carboxylic acid tert-butyl ester 
• 13735-81-4 1-styrenyloxytrimethylsilane 
• 2294-74-8 1-phenyl-2-pyridin-2-yl-ethanol 
• 100-52-7 benzaldehyde 
• 109-06-8 α-picoline 
• 73853-37-9 1-phenyl-2-(piperidin-2-yl)ethan-1-ol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 138371-96-7 tert-butyl 2-(2-oxo-2-phenylethyl)piperidine-1-carboxylate 

Downstream Products

• 70561-76-1 (±)-allosedamine 
• 497-88-1 sedamine 
• 497-88-1 (-)-sedamine 
• 1070913-20-0 (R)-1-phenyl-2-[N(1')-(tert-butoxycarbonyl)piperidin-2'-yl]ethanone 
• 639458-44-9 (S,S)-2-(2-hydroxy-2-phenyl-ethyl)-piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

Decarboxylative Conjunctive Cross-coupling of Vinyl Boronic Esters using Metallaphotoredox Catalysis

The synthesis of complex alkyl boronic esters through conjunctive cross-coupling of vinyl boronic esters with carboxylic acids and aryl iodides is described. The reaction proceeds under mild metallaphotoredox conditions and involves an unprecedented decarboxylative radical addition/cross-coupling cascade of vinyl boronic esters. Excellent functional-group tolerance is displayed, and application of a range of carboxylic acids, including secondary α-amino acids, and aryl iodides provides efficient access to highly functionalized alkyl boronic esters. The decarboxylative conjunctive cross-coupling was also applied to the synthesis of sedum alkaloids.

Enantioselective synthesis of lobeline via nonenzymatic desymmetrization

Lobeline has been prepared in enantiopure form via desymmetrization of lobelanidine with use of BTM, a nonenzymatic enantioselective acyl transfer catalyst.