73853-37-9

Basic information

• Product Name: 1-phenyl-2-(piperidin-2-yl)ethanol
• CAS NO: 73853-37-9
• Molecular Formula: C₁₃H₁₉NO
• Molecular Weight: 205.2961
• Mol File: 73853-37-9.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 352.9°C at 760 mmHg
• Flash Point: 129.8°C
• Density: 1.031g/cm³
• Vapor Pressure: 1.37E-05mmHg at 25°C
• Refractive Index: 1.532
• CAS DataBase Reference: 1-phenyl-2-(piperidin-2-yl)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-2-(piperidin-2-yl)ethanol(73853-37-9)
• EPA Substance Registry System: 1-phenyl-2-(piperidin-2-yl)ethanol(73853-37-9)

Safety Data

• Hazardous Substances Data: 73853-37-9(Hazardous Substances Data)

Usage

Appearance

White solid at room temperature

Molecular weight

231.33 g/mol
Contains a phenyl group and a piperidine ring
Has a hydroxyl group attached to the carbon chain

Potential use

Pharmaceutical intermediate and research chemical

Possible applications

Synthesis of pharmacologically active compounds
May have biological activity of its own
Additional research may reveal further potential uses for this compound.

Upstream product

• 70546-85-9 2-phenyl-3,3a,4,5,6,7-hexahydro-2H-isoxazolo<2,3-a>pyridine 
• 1462-92-6 6-methyl-2,3,4,5-tetrahydro-pyridine 
• 100-52-7 benzaldehyde 
• 4801-58-5 N-hydroxypiperidine 
• 34418-91-2 2,3,4,5-tetrahydropyridine N-oxide 
• 130721-64-1 (Z)-1-phenyl-2-piperidin-2-ylideneethanone 
• 30800-90-9 1-phenyl-2-(piperidin-2-yl)ethan-1-one 
• 134040-02-1 (R)-2-((R)-2-Hydroxy-2-phenyl-ethyl)-piperidine-1-carboxylic acid methyl ester 
• 13735-81-4 1-styrenyloxytrimethylsilane 
• 85908-96-9 2-oxopiperidine-1-carboxylic acid tert-butyl ester 
• 119910-09-7 N-tert-butoxycarbonyl-2-ethoxypiperidine 
• 138371-96-7 tert-butyl 2-(2-oxo-2-phenylethyl)piperidine-1-carboxylate 
• 76469-99-3 1-(carbomethoxy)-2-phenacylpiperidine 
• 94617-78-4 2-phenylpiperidino<1,2-b>isoxazolidine 

Downstream Products

• 495-47-6 1-phenyl-2-[(2S)-piperidin-2-yl]-(1R)-ethan-1-ol 
• 112653-26-6 (1S)-1-Phenyl-2<(2R)-2-piperidyl>ethanol 
• 127983-45-3 6-(2'-hydroxy-2'-phenylethyl)-2,3,4,5-tetrahydropyridine 
• 127983-46-4 cis-6-methyl-8-phenyl-9-oxa-1-azabicyclo<4.3.0>nonane 
• 131697-74-0 (2S,3aR)-8-Benzyl-3a-methyl-2-phenyl-hexahydro-isoxazolo[2,3-a]pyridin-8-ium; bromide 
• 111612-22-7 (1R)-1-Phenyl-2<(2R)-2-piperidyl>ethanol 
• 1415-36-7 (-)-norsedamine 
• 497-88-1 sedamine 
• 111528-22-4 (1R,3R)-1-(4-Nitro-phenyl)-3-phenyl-hexahydro-pyrido[1,2-c][1,3]oxazine 
• 95294-68-1 3-phenyl-hexahydro-pyrido[1,2-c][1,3]oxazine 
• 95770-80-2 3-phenylhexahydro-1H,3H-pyrido[1,2-c][1,3]oxazin-1-one 
• 102960-85-0 1,3-diphenyl-hexahydro-pyrido[1,2-c][1,3]oxazine 
• 138371-97-8 (1RS,2SR) N-tert-butoxycarbonyl-2-(β-hydroxy-β-phenylethyl)piperidine 
• 138371-97-8 (1SR,2SR) N-tert-butoxycarbonyl-2-(β-hydroxy-β-phenylethyl)piperidine 

Relevant articles and documents

Intermolecular [4 + 2] process of N-acyliminium ions with simple olefins for construction of functional substituted-1,3-oxazinan-2-ones

An efficient approach to functionalized 4,6-disubstituted-and 4,6,6-trisubstituted-1,3-oxazinan-2-ones skeleton has been developed through the reaction of semicyclic N,O-acetals 4a and 4b with 1,1-disubstituted ethylenes 5 or 8. As a result of such a [4 +

A rapid access to (±)-sedamine and some original N -benzyl unsaturated analogues

Reduction of N-alkyl-2-(2-hydroxy-2-phenylethyl)pyridinium salts using excess of sodium triacetoxyborohydride afforded exclusively the corresponding tetrahydropyridine derivative bearing a piperidine ring with a double bond in the 3,4-position. Furthermore, under these conditions, syn-1,3-amino alcohols were obtained in good yield and diastereoselectivity. Georg Thieme Verlag Stuttgart · New York.

Enantioselective synthesis of lobeline via nonenzymatic desymmetrization

Lobeline has been prepared in enantiopure form via desymmetrization of lobelanidine with use of BTM, a nonenzymatic enantioselective acyl transfer catalyst.