1413429-75-0

Basic information

• Product Name: diethyl {4-[(1-methyl-1H-benzimidazol-2-yl)methoxy]benzylidene}propanedioate
• Synonyms: diethyl {4-[(1-methyl-1H-benzimidazol-2-yl)methoxy]benzylidene}propanedioate
• CAS NO: 1413429-75-0
• Molecular Weight: 408.454
• Mol File: 1413429-75-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diethyl {4-[(1-methyl-1H-benzimidazol-2-yl)methoxy]benzylidene}propanedioate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl {4-[(1-methyl-1H-benzimidazol-2-yl)methoxy]benzylidene}propanedioate(1413429-75-0)
• EPA Substance Registry System: diethyl {4-[(1-methyl-1H-benzimidazol-2-yl)methoxy]benzylidene}propanedioate(1413429-75-0)

Safety Data

• Hazardous Substances Data: 1413429-75-0(Hazardous Substances Data)

Upstream product

• 25148-68-9 N-methylbenzene-1,2-diamine dihydrochloride 
• 118001-75-5 4-<(1-methyl-2-1H-benzimidazolyl)methoxy>benzaldehyde 
• 105-53-3 diethyl malonate 
• 123-08-0 4-hydroxy-benzaldehyde 
• 4760-35-4 2-chloromethyl-1-methyl-1H-benzimidazole 
• 459-57-4 4-fluorobenzaldehyde 
• 7467-35-8 (1-methyl-1H-benzimidazol-2-yl)methanol 

Downstream Products

• 1413429-76-1 diethyl {4-[(1-methyl-1H-benzimidazol2-yl)methoxy]benzyl}propanedioate 

Relevant articles and documents

Heterocyclyl linked anilines and benzaldehydes as precursors for biologically significant new chemical entities

Benzylidene and benzyl thiazolidinediones, oxazolidinediones, isoxazolidinediones and their acyclic analogs like alpha alkylthio/alkoxy phenylpropanoic acids, beta-keto esters and tyrosine-based compounds possess broad therapeutic potential in general and as Peroxisome Proliferator Activated Receptors (PPARs) agonists in particular in the management of hyperglycemia and hyperlipidaemia for the treatment of Type 2 Diabetes (T2D). We have synthesised and characterized some novel and suitably substituted heterocyclyl linked benzaldehydes and anilines, which can be easily and very readily derivatized to all the above mentioned classes to generate new chemical entities of broader biological significance. Synthesis of their benzylidene thiazolidinedione and diethyl malonate and also benzyl diethyl malonate and alpha-bromoesters derivatives is reported in some of the cases in the present work. Indian Academy of Sciences.