141368-26-5

Basic information

• Product Name: Benzenesulfonamide, 4-methyl-N-[2-(4-methylbenzoyl)phenyl]-
• CAS NO: 141368-26-5
• Molecular Formula: C21H19NO3S
• Molecular Weight: 365.453
• Mol File: 141368-26-5.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, 4-methyl-N-[2-(4-methylbenzoyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, 4-methyl-N-[2-(4-methylbenzoyl)phenyl]-(141368-26-5)
• EPA Substance Registry System: Benzenesulfonamide, 4-methyl-N-[2-(4-methylbenzoyl)phenyl]-(141368-26-5)

Safety Data

• Hazardous Substances Data: 141368-26-5(Hazardous Substances Data)

Upstream product

• 6311-23-5 2-(toluene-4-sulfonylamino)-benzoic acid 
• 36192-63-9 2-amino-4'-methylbenzophenone 
• 98-59-9 p-toluenesulfonyl chloride 
• 941-55-9 4-toluenesulfonyl azide 
• 134-84-9 4-Methylbenzophenone 
• 6590-65-4 N-(2-Formyl-phenyl)-4-methyl-benzenesulfonamide 
• 624-31-7 4-tolyl iodide 
• 118-92-3 anthranilic acid 
• 610-14-0 2-nitrobenzyl chloride 
• 108-88-3 toluene 
• 71319-20-5 (4-methylphenyl)(2-nitrophenyl)methanone 
• 42840-02-8 2-(Toluene-4-sulfonylamino)-benzoyl chloride 

Downstream Products

• 36192-63-9 2-amino-4'-methylbenzophenone 
• 19434-30-1 2-hydroxy-4'-methylbenzophenone 
• 1705-89-1 3-methyl-9H-fluoren-9-one 
• 500870-81-5 2-N-(4-methylsulfonylbenzoyl)-amide-4'-methyl-benzophenone 
• 500870-82-6 2-N-(4-aminosulfonylbenzoyl)-amide-4'-methyl-benzophenone 
• 141368-12-9 3-methyl-9-<3--1-propylamino>-fluorene-9-carbonitrile 
• 1238251-80-3 N-(2-(1-hydroxy-3-phenyl-1-(p-tolyl)prop-2-yn-1-yl)phenyl)-4-methylbenzenesulfonamide 
• 1238252-13-5 N-(2-(1-hydroxy-1-p-tolylprop-2-ynyl)phenyl)-4-methylbenzenesulfonamide 
• 1261245-26-4 N-(2-(1-hydroxy-1-p-tolylbut-3-enyl)phenyl)-4-methylbenzenesulfonamide 
• 1334483-35-0 5-(p-tolyl)-1-tosyl-2,3-dihydro-1H-benzo[b]azepine 
• 1334483-26-9 1-cyclopropyl-1-(2-(tosylamino)phenyl)(p-tolyl)methanol 
• 1315477-64-5 3-p-tolyl-1-tosyl-1H-indole-2-carbaldehyde 
• 1315477-88-3 (E)-2-(iodomethylene)-3-(p-tolyl)-1-tosylindolin-3-ol 
• 1351557-18-0 6-methyl-11-(p-tolyl)-6H-indolo[2,3-b]quinoline 

Relevant articles and documents

Rhodium-Catalyzed Directing-Group-Assisted Aldehydic C–H Arylations with Aryl Halides

A rhodium-catalyzed general protocol for the directing-group-assisted arylation of aromatic aldehydic C–H bonds was developed. This method involves either hydroxy- or amino-group-directed aldehyde C–H arylation with various aryl halides. A broad synthetic scope for the preparation of 2-hydroxybenzophenones was established with electronically variant salicylaldehydes and aryl halides with chemo- and regioselective possibilities. The developed protocol was also applied in the synthesis of medicinally important 3-salicyloylpyridines in high yields.

1-(2′-Anilinyl)prop-2-yn-1-ol rearrangement for oxindole synthesis

A synthetic method that relies on NIS (N-iodosuccinimide)-mediated cycloisomerization reactions of 1-(2′-anilinyl)prop-2-yn-1-ols to gem-3-(diiodomethyl)indolin-2-ones and 2-(iodomethylene)indolin-3-ones has been developed. The reactions were shown to be chemoselective, with secondary and tertiary alcoholic substrates exclusively giving the 3- and 2-oxindole products, respectively. In the case of the latter, the transformation features an unprecedented double 1,2-OH and 1,2-alkyl migration relay. Density functional theory (DFT) calculations based on proposed iodoaminocyclization species provide insight into this unique divergence in product selectivity. Copyright

Ru(ii)-catalyzed intermolecular ortho-C-H amidation of aromatic ketones with sulfonyl azides

Ru(ii)-catalyzed intermolecular ortho-C-H amidation of weakly coordinating aromatic ketones with sulfonyl azides is reported. The developed reaction protocol can be extended to various substituted aromatic ketones to afford a wide range of desired C-N bond formation products in good yields.