1428946-58-0

Basic information

• Product Name: (20S)-1α,25-dihydroxy-2-methylene vitamin D₃
• Synonyms: (20S)-1α,25-dihydroxy-2-methylene vitamin D₃
• CAS NO: 1428946-58-0
• Molecular Weight: 428.656
• Mol File: 1428946-58-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (20S)-1α,25-dihydroxy-2-methylene vitamin D₃(CAS DataBase Reference)
• NIST Chemistry Reference: (20S)-1α,25-dihydroxy-2-methylene vitamin D₃(1428946-58-0)
• EPA Substance Registry System: (20S)-1α,25-dihydroxy-2-methylene vitamin D₃(1428946-58-0)

Safety Data

• Hazardous Substances Data: 1428946-58-0(Hazardous Substances Data)

Upstream product

• 1451070-65-7 (3aR,4R,6R,7aR)-4,6-bis[(tert-butyldimethylsilyl)oxy]-5-methylene-3,3a,4,5,6,7-hexahydroindazole-7a-carboxylic acid methyl ester 
• 1227058-14-1 (3R,5R)-3,5-bis[(tert-butyldimethylsilyl)oxy]-4-methylene-cyclohex-1-enecarboxylic acid methyl ester 
• 213250-59-0 methyl (3R,5R)-3,5-bis[(tert-butyldimethylsilyl)oxy]-1-hydroxy-4-methylenecyclohexanecarboxylate 
• 1428946-46-6 (3R,5R)-3,5-bis[(tert-butyldimethylsilyl)oxy]-2-methyl-4-methylene-cyclohex-1-enecarbaldehyde 
• 101906-39-2 Methyl (3R,4R,5R)-3,5-Bis<(tert-butyl)dimethylsilyloxy>-4-hydroxycyclohex-1-ene-1-carboxylate 
• 1451070-71-5 (20S)-1α-[(tert-butyldimethylsilyl)oxy]-2-methylene-25-[(triethylsilyl)oxy]vitamin D₃ tert-butyl dimethylsilyl ether 
• 1451070-67-9 (20S)-1α,3β-bis[(tert-butyldimethylsilyl)oxy]-2-methylene-25-[(triethylsilyl)oxy]-9,10-secocholesta-5(10),8-dien-6-yne 
• 852380-64-4 (3R,5R)-5-[(tert-butyldimethylsilyl)oxy]-1,3-dihydroxy-4-methylene-cyclohexanecarboxylic acid methyl ester 
• 766529-88-8 (1R,3R,5R)-1-acetoxy-3-[(tert-butyldimethylsilyl)oxy]-6-oxa-bicyclo[3.2.1]octane-4,7-dione 

Downstream Products

• 1428946-59-1 (5E)-(20S)-1α,25-dihydroxy-2-methylene vitamin D₃ 

Relevant articles and documents

SYNTHESIS AND BIOLOGICAL ACTIVITY OF 2-METHYLENE ANALOGS OF CALCITRIOL AND RELATED COMPOUNDS

Disclosed are 2-methylene analogs of vitamin D3 and related compounds, their biological activities, and various pharmaceutical uses for these analogs. Particularly disclosed are 1α-hydroxy-2-methylene-vitamin D3, (20S)-1α-hydroxy-2-m

2-methylene-vitamin D analogs and their uses

This invention discloses 2-methylene-vitamin D analogs, and specifically (20S)-1α,25 -dihydroxy-2-methylene-vitamin D3 as well as (5E)-(20S)-1α,25-dihydroxy-2 -methylene-vitamin D3 and (20R)-1α,25-dihydroxy-2-methylene-vitamin D