852380-64-4

Basic information

• Product Name: (3R,5R)-5-[(tert-butyldimethylsilyl)oxy]-1,3-dihydroxy-4-methylene-cyclohexanecarboxylic acid methyl ester
• Synonyms: (3R,5R)-5-[(tert-butyldimethylsilyl)oxy]-1,3-dihydroxy-4-methylene-cyclohexanecarboxylic acid methyl ester
• CAS NO: 852380-64-4
• Molecular Weight: 316.47
• Mol File: 852380-64-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (3R,5R)-5-[(tert-butyldimethylsilyl)oxy]-1,3-dihydroxy-4-methylene-cyclohexanecarboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,5R)-5-[(tert-butyldimethylsilyl)oxy]-1,3-dihydroxy-4-methylene-cyclohexanecarboxylic acid methyl ester(852380-64-4)
• EPA Substance Registry System: (3R,5R)-5-[(tert-butyldimethylsilyl)oxy]-1,3-dihydroxy-4-methylene-cyclohexanecarboxylic acid methyl ester(852380-64-4)

Safety Data

• Hazardous Substances Data: 852380-64-4(Hazardous Substances Data)

Upstream product

• 77-95-2 D-(-)-quinic acid 
• 163217-18-3 (1R,3R,4S,5R)-3-[(tert-butyldimethylsilyl)oxy]-1,4-dihydroxy-6-oxa-bicyclo[3.2.1]octan-7-one 
• 665-27-0 1,5-quinide 
• 124-41-4 sodium methylate 
• 766529-94-6 (1R,3R,5R)-3-[(tert-butyldimethylsilyl)oxy]-1-hydroxy-6-oxa-bicyclo[3.2.1]octane-4,7-dione 

Downstream Products

• 1451070-67-9 (20S)-1α,3β-bis[(tert-butyldimethylsilyl)oxy]-2-methylene-25-[(triethylsilyl)oxy]-9,10-secocholesta-5(10),8-dien-6-yne 
• 1451070-71-5 (20S)-1α-[(tert-butyldimethylsilyl)oxy]-2-methylene-25-[(triethylsilyl)oxy]vitamin D₃ tert-butyl dimethylsilyl ether 
• 1428946-58-0 (20S)-1α,25-dihydroxy-2-methylene vitamin D₃ 
• 1428946-59-1 (5E)-(20S)-1α,25-dihydroxy-2-methylene vitamin D₃ 
• 213250-59-0 methyl (3R,5R)-3,5-bis[(tert-butyldimethylsilyl)oxy]-1-hydroxy-4-methylenecyclohexanecarboxylate 
• 1227058-14-1 (3R,5R)-3,5-bis[(tert-butyldimethylsilyl)oxy]-4-methylene-cyclohex-1-enecarboxylic acid methyl ester 

Relevant articles and documents

SYNTHESIS AND BIOLOGICAL ACTIVITY OF 2-METHYLENE ANALOGS OF CALCITRIOL AND RELATED COMPOUNDS

Disclosed are 2-methylene analogs of vitamin D3 and related compounds, their biological activities, and various pharmaceutical uses for these analogs. Particularly disclosed are 1α-hydroxy-2-methylene-vitamin D3, (20S)-1α-hydroxy-2-m

2-methylene-vitamin D analogs and their uses

This invention discloses 2-methylene-vitamin D analogs, and specifically (20S)-1α,25 -dihydroxy-2-methylene-vitamin D3 as well as (5E)-(20S)-1α,25-dihydroxy-2 -methylene-vitamin D3 and (20R)-1α,25-dihydroxy-2-methylene-vitamin D