1456-67-3

Basic information

• Product Name: 1,3,4-Thiadiazole, 2-(4-methoxyphenyl)-5-phenyl-
• CAS NO: 1456-67-3
• Molecular Formula: C15H12N2OS
• Molecular Weight: 268.339
• Mol File: 1456-67-3.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 1,3,4-Thiadiazole, 2-(4-methoxyphenyl)-5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,4-Thiadiazole, 2-(4-methoxyphenyl)-5-phenyl-(1456-67-3)
• EPA Substance Registry System: 1,3,4-Thiadiazole, 2-(4-methoxyphenyl)-5-phenyl-(1456-67-3)

Safety Data

• Hazardous Substances Data: 1456-67-3(Hazardous Substances Data)

Usage

Type of compound

Heterocyclic organic compound

Structure

Contains a sulfur atom within a five-membered ring of two nitrogen atoms and two carbon atoms

Common use

Building block for the synthesis of various pharmaceuticals and bioactive molecules

Applications

a. Medicinal chemistry
b. Potential use in the development of new drugs with therapeutic applications
c. Anti-fungal, anti-bacterial, and anti-cancer agents
d. Potential application as a corrosion inhibitor in materials science

Upstream product

• 233605-26-0 N-thiobenzoyl-phthalimide 
• 3290-99-1 4-methoxybenzoic acid hydrazide 
• 5310-14-5 N-methylthiobenzamide 
• 62625-55-2 4-methoxy-thiobenzoic acid hydrazide 
• 2362-64-3 p-methoxythiobenzamide 
• 32252-82-7 1-chloro-1,4-diphenyl-2,3-diazabutadiene 
• 6781-59-5 1-benzoyl-2-(4-methoxybenzoyl)hydrazine 
• 121-98-2 methyl 4-methoxybenzoate 
• 100-09-4 4-methoxybenzoic acid 
• 98-88-4 benzoyl chloride 
• 5953-85-5 p-anisaldehyde hydrazone 
• 123-11-5 4-methoxy-benzaldehyde 
• 2168-78-7 methyl dithiobenzoate 
• 14850-86-3 N'-(4-methoxybenzylidene)benzohydrazide 

Downstream Products

• 1214913-31-1 2-[4-(5-phenyl-1,3,4-thiadiazole-2-yl)-phenoxy] ethanol 
• 1214913-30-0 4-(5-phenyl-1,3,4-thiadiazole-2-yl) phenol 

Relevant articles and documents

Structural studies of 2,5-disubstituted 1,3,4-thiadiazole derivatives from dithioesters under the mild condition: Studies on antioxidant, antimicrobial activities, and molecular docking

A series of 2,5-disubstituted 1,3,4-thiadiazole was synthesized and evaluated for their antioxidant and molecular docking studies. These molecules were efficiently synthesized under mild and inexpensive starting material. Construction of these molecules developed using substituted aldehydes and substituted dithioesters in presence of NCS (N-Chorosuccinimide). The compounds 4a, 4b, 4c, 4f, and 4k showed good antibacterial and antioxidant activity among which, 4k possess excellent antibacterial and antioxidant activity. The results of antioxidant activity studies revealed that compound 4k manifested profound antioxidant potential. The molecular docking study was performed with respective newly synthesized compounds to ascertain the binding mode of 4k with respect to the critical proteins involved in biosynthesis and metabolic pathways.

Preparation method and application of multifunctional ultraviolet absorbent

The invention relates to a preparation method and application of a multifunctional ultraviolet absorbent for terylene. The general structural formula of the absorbent is as follows: formula, wherein Y is a quaternary ammonium salt group. According to the preparation method and application of the multifunctional ultraviolet absorbent for terylene disclosed by the invention, the dyeing mode of the ultraviolet absorbent to terylene is similar to disperse dyes, and fabrics can be subjected to anti-ultraviolet finishing by using a high-temperature and high-pressure exhausting method and can also be dyed with the disperse dyes in the same bath; the finished fabrics not only have good anti-ultraviolet properties, but also have the effects of killing or inhibiting Gram-positive bacteria and Gram-negative bacteria represented by staphylococcus aureus and Escherichia coli; and meanwhile, the fabrics have good anti-static function.

C-H arylation of azaheterocycles: A direct ligand-free and Cu-catalyzed approach using diaryliodonium salts

An efficient and high yielding Cu-catalyzed direct C-H arylation of azaheterocycles including oxadiazoles, thiadiazoles, benzoxazoles and benzothiazoles has been achieved by employing easily accessible diaryliodonium salts. the Partner Organisations 2014.